(Q46250306)

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Amyloid-beta peptide (Abeta) neurotoxicity is modulated by the rate of peptide aggregation: Abeta dimers and trimers correlate with neurotoxicity

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Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/19005060

Amyloid-beta peptide (Abeta) neurotoxicity is modulated by the rate of peptide aggregation: Abeta dimers and trimers correlate with neurotoxicity (English)

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Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/19005060

1 reference

based on heuristic

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toxic encephalopathy

1 reference

based on heuristic

inferred from title

7

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6671645&resulttype=core&format=json

16 May 2020

8

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6671645&resulttype=core&format=json

16 May 2020

author name string

Lin Wai Hung

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6671645&resulttype=core&format=json

16 May 2020

Giuseppe D Ciccotosto

2

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6671645&resulttype=core&format=json

16 May 2020

Eleni Giannakis

3

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PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6671645&resulttype=core&format=json

16 May 2020

Deborah J Tew

4

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PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6671645&resulttype=core&format=json

16 May 2020

Keyla Perez

5

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6671645&resulttype=core&format=json

16 May 2020

Kevin J Barnham

9

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6671645&resulttype=core&format=json

16 May 2020

Colin L Masters

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6671645&resulttype=core&format=json

16 May 2020

language of work or name

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publication date

1 November 2008

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/19005060

Journal of Neuroscience

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6671645&resulttype=core&format=json

16 May 2020

28

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6671645&resulttype=core&format=json

16 May 2020

46

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6671645&resulttype=core&format=json

16 May 2020

11950-11958

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6671645&resulttype=core&format=json

16 May 2020

Recognition sequence design for peptidyl modulators of beta-amyloid aggregation and toxicity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In situ atomic force microscopy study of Alzheimer's beta-amyloid peptide on different substrates: new insights into mechanism of beta-sheet formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A molecular model of Alzheimer amyloid beta-peptide fibril formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Profiling of amyloid beta peptide variants using SELDI Protein Chip arrays

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The GxxxG motif: a framework for transmembrane helix-helix association

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that the beta-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of abeta by zinc

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oligomerizaiton and fibril asssembly of the amyloid-beta protein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on the in vitro assembly of a beta 1-40: implications for the search for a beta fibril formation inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease: genes, proteins, and therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and characterization of key kinetic intermediates in amyloid beta-protein fibrillogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improved preparation of amyloid-beta peptides using DBU as Nalpha-Fmoc deprotection reagent.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure and location of amyloid beta peptide chains and arrays in Alzheimer's disease: new findings require reevaluation of the amyloid hypothesis and of tests of the hypothesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DICHROWEB: an interactive website for the analysis of protein secondary structure from circular dichroism spectra.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

gamma-Secretase, Notch, Abeta and Alzheimer's disease: where do the presenilins fit in?

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GXXXG and AXXXA: common alpha-helical interaction motifs in proteins, particularly in extremophiles

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Annexin 5 and apolipoprotein E2 protect against Alzheimer's amyloid-beta-peptide cytotoxicity by competitive inhibition at a common phosphatidylserine interaction site

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rationalization of the effects of mutations on peptide and protein aggregation rates.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotoxic, redox-competent Alzheimer's beta-amyloid is released from lipid membrane by methionine oxidation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid fibril formation requires a chemically discriminating nucleation event: studies of an amyloidogenic sequence from the bacterial protein OsmB

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relative influence of hydrophobicity and net charge in the aggregation of two homologous proteins.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dimeric amyloid beta protein rapidly accumulates in lipid rafts followed by apolipoprotein E and phosphorylated tau accumulation in the Tg2576 mouse model of Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monitoring the process of HypF fibrillization and liposome permeabilization by protofibrils

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cortical synaptic integration in vivo is disrupted by amyloid-beta plaques.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oligomers on the brain: the emerging role of soluble protein aggregates in neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammation occurs early during the Abeta deposition process in TgCRND8 mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced toxicity and cellular binding of a modified amyloid beta peptide with a methionine to valine substitution

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylation of the imidazole side chains of the Alzheimer disease amyloid-beta peptide results in abolition of superoxide dismutase-like structures and inhibition of neurotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Surface behavior and lipid interaction of Alzheimer beta-amyloid peptide 1-42: a membrane-disrupting peptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural role of glycine in amyloid fibrils formed from transmembrane alpha-helices

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A specific amyloid-beta protein assembly in the brain impairs memory

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plaques and tangles and the pathogenesis of Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Copper-mediated amyloid-beta toxicity is associated with an intermolecular histidine bridge.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Optimization and evaluation of surface-enhanced laser-desorption/ionization time-of-flight mass spectrometry for protein profiling of cerebrospinal fluid

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroserpin binds Abeta and is a neuroprotective component of amyloid plaques in Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GxxxG motifs within the amyloid precursor protein transmembrane sequence are critical for the etiology of Abeta42.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accelerating amyloid-beta fibrillization reduces oligomer levels and functional deficits in Alzheimer disease mouse models.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cell-selective neurotoxicity of the Alzheimer's Abeta peptide is determined by surface phosphatidylserine and cytosolic ATP levels. Membrane binding is required for Abeta toxicity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dimeric structures of alpha-synuclein bind preferentially to lipid membranes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative evaluation of congo red binding to amyloid-like proteins with a beta-pleated sheet conformation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevalence of Alzheimer's disease in a community population of older persons. Higher than previously reported.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid plaque core protein in Alzheimer disease and Down syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinically diagnosed Alzheimer's disease: autopsy results in 150 cases.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and partial characterization of neurofibrillary tangles and amyloid plaque core in Alzheimer's disease: immunohistological studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A simple method for displaying the hydropathic character of a protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aggregation of secreted amyloid beta-protein into sodium dodecyl sulfate-stable oligomers in cell culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Morphology and toxicity of Abeta-(1-42) dimer derived from neuritic and vascular amyloid deposits of Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta-protein fibrillogenesis. Detection of a protofibrillar intermediate.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Common core structure of amyloid fibrils by synchrotron X-ray diffraction.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure-based prediction of the stability of transmembrane helix-helix interactions: the sequence dependence of glycophorin A dimerization

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

1 reference

https://pubmed.ncbi.nlm.nih.gov/19005060

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.3916-08.2008

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6671645&resulttype=core&format=json

16 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6671645&resulttype=core&format=json

16 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6671645&resulttype=core&format=json

16 May 2020

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