(Q33993301)

30 July 2017

title

Loss of stearoyl-CoA desaturase 1 rescues cardiac function in obese leptin-deficient mice (English)

1 reference

30 July 2017

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Pawel Dobrzyn

1

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Agnieszka Dobrzyń

object named as

Agnieszka Dobrzyn

series ordinal

2

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author name string

Makoto Miyazaki

series ordinal

3

1 reference

30 July 2017

James M Ntambi

series ordinal

4

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30 July 2017

publication date

2 April 2010

1 reference

Journal of Lipid Research

30 July 2017

published in

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30 July 2017

volume

51

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30 July 2017

issue

8

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30 July 2017

page(s)

2202-2210

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Stearoyl-CoA desaturase-1 deficiency attenuates obesity and insulin resistance in leptin-resistant obese mice

30 July 2017

cites work

1 reference

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Ceramide is a cardiotoxin in lipotoxic cardiomyopathy

5 July 2018

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Decreased p110alpha catalytic activity accompanies increased myocyte apoptosis and cardiac hypertrophy in leptin deficient ob/ob mice

5 July 2018

1 reference

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Loss of stearoyl-CoA desaturase 1 inhibits fatty acid oxidation and increases glucose utilization in the heart

5 July 2018

1 reference

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Forgotten but not gone: the rediscovery of fatty heart, the most common unrecognized disease in America

5 July 2018

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Ceramide: physiological and pathophysiological aspects

5 July 2018

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PPAR gamma and human metabolic disease

5 July 2018

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Cardiac myocyte apoptosis is associated with increased DNA damage and decreased survival in murine models of obesity

5 July 2018

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Peroxisome proliferator-activated receptor delta (PPARdelta) activation protects H9c2 cardiomyoblasts from oxidative stress-induced apoptosis

5 July 2018

1 reference

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Stearoyl-CoA desaturase-1 deficiency reduces ceramide synthesis by downregulating serine palmitoyltransferase and increasing beta-oxidation in skeletal muscle

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903830

Hyperleptinemia prevents lipotoxic cardiomyopathy in acyl CoA synthase transgenic mice

5 July 2018

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Carnitine palmitoyltransferase-I, a new target for the treatment of heart failure: perspectives on a shift in myocardial metabolism as a therapeutic intervention

5 July 2018

1 reference

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Stearoyl-CoA desaturase 1 deficiency increases fatty acid oxidation by activating AMP-activated protein kinase in liver.

5 July 2018

1 reference

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A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

5 July 2018

1 reference

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Stearoyl-CoA desaturase 1 deficiency elevates insulin-signaling components and down-regulates protein-tyrosine phosphatase 1B in muscle

5 July 2018

1 reference

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Minireview: weapons of lean body mass destruction: the role of ectopic lipids in the metabolic syndrome

5 July 2018

1 reference

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Disruption of leptin signaling contributes to cardiac hypertrophy independently of body weight in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903830

Cardiac lipid accumulation associated with diastolic dysfunction in obese mice.

5 July 2018

1 reference

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Identification and characterization of murine SCD4, a novel heart-specific stearoyl-CoA desaturase isoform regulated by leptin and dietary factors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903830

Serine palmitoyltransferase, a key enzyme of sphingolipid metabolism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903830

Ceramide accumulation precedes caspase-3 activation during apoptosis of A549 human lung adenocarcinoma cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903830

Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903830

Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903830

Oxidative injury due to chronic nitric oxide synthase inhibition in rat: effect of regular exercise on the heart

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903830

Hypertrophic cardiomyopathy in cardiac myosin binding protein-C knockout mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903830

Oleoyl-CoA is the major de novo product of stearoyl-CoA desaturase 1 gene isoform and substrate for the biosynthesis of the Harderian gland 1-alkyl-2,3-diacylglycerol

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903830

Involvement of caspase 3- and 8-like proteases in ceramide-induced apoptosis of cardiomyocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903830

Lipotoxic heart disease in obese rats: implications for human obesity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903830

Regulation of fatty acid homeostasis in cells: novel role of leptin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903830

Lipoapoptosis in beta-cells of obese prediabetic fa/fa rats. Role of serine palmitoyltransferase overexpression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903830

Ceramide is involved in triggering of cardiomyocyte apoptosis induced by ischemia and reperfusion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903830

Influence of Bax or Bcl-2 overexpression on the ceramide-dependent apoptotic pathway in glioma cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903830

A functional role for the B56 alpha-subunit of protein phosphatase 2A in ceramide-mediated regulation of Bcl2 phosphorylation status and function

28 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1194%2FJLR.M003780

Oxidation of oleic and elaidic acids in rat and human heart homogenates

21 January 2018

1 reference

12 December 2020

Calcium and 2-oxoglutarate-mediated control of aspartate formation by rat heart mitochondria

1 reference

12 December 2020

Nitric oxide-enhanced caspase-3 and acidic sphingomyelinase interaction: a novel mechanism by which airway epithelial cells escape ceramide-induced apoptosis

1 reference

12 December 2020

Serine palmitoyltransferase

1 reference

12 December 2020

Identifiers

DOI

10.1194/JLR.M003780

1 reference

30 July 2017

1 reference

30 July 2017

1 reference