(Q33994966)

30 July 2017

title

Estrogen receptor alpha mediates 17alpha-ethynylestradiol causing hepatotoxicity (English)

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30 July 2017

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Yukio Yamamoto

1

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Masahiko Negishi

object named as

Masahiko Negishi

8

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Kenneth S. Korach

object named as

Kenneth S Korach

6

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author name string

Rick Moore

2

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30 July 2017

Holly A Hess

3

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30 July 2017

Grace L Guo

4

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30 July 2017

Frank J Gonzalez

5

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30 July 2017

Robert R Maronpot

7

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30 July 2017

language of work or name

English

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publication date

10 April 2006

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Journal of Biological Chemistry

30 July 2017

published in

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30 July 2017

volume

281

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30 July 2017

issue

24

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30 July 2017

page(s)

16625-16631

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Review: intrahepatic cholestasis. A puzzling disorder of pregnancy

30 July 2017

cites work

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Complementary roles of farnesoid X receptor, pregnane X receptor, and constitutive androstane receptor in protection against bile acid toxicity

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Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.

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A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis

21 January 2018

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Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors

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Human bile salt export pump promoter is transactivated by the farnesoid X receptor/bile acid receptor.

21 January 2018

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The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

21 January 2018

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An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids.

21 January 2018

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Interactions between hepatic Mrp4 and Sult2a as revealed by the constitutive androstane receptor and Mrp4 knockout mice

21 January 2018

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The constitutive androstane receptor and pregnane X receptor function coordinately to prevent bile acid-induced hepatotoxicity

21 January 2018

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Combined loss of orphan receptors PXR and CAR heightens sensitivity to toxic bile acids in mice

21 January 2018

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Nuclear receptors constitutive androstane receptor and pregnane X receptor ameliorate cholestatic liver injury

21 January 2018

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Estrogen Receptor Null Mice: What Have We Learned and Where Will They Lead Us?

21 January 2018

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Diverse roles of the nuclear orphan receptor CAR in regulating hepatic genes in response to phenobarbital

21 January 2018

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Hepatocyte Nuclear Factor 4α Is a Central Regulator of Bile Acid Conjugation

21 January 2018

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The role of the nuclear receptor CAR as a coordinate regulator of hepatic gene expression in defense against chemical toxicity.

21 January 2018

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Protective role of hydroxysteroid sulfotransferase in lithocholic acid-induced liver toxicity

21 January 2018

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Tissue distribution and quantitative analysis of estrogen receptor-alpha (ERalpha) and estrogen receptor-beta (ERbeta) messenger ribonucleic acid in the wild-type and ERalpha-knockout mouse

21 January 2018

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The role of orphan nuclear receptors in the regulation of cholesterol homeostasis

21 January 2018

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The enzymes, regulation, and genetics of bile acid synthesis

21 January 2018

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21 January 2018

Genes and cholestasis.

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Hepatobiliary transporter expression in percutaneous liver biopsies of patients with cholestatic liver diseases.

21 January 2018

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Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion

21 January 2018

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Estrogen receptor alpha, but not beta, plays a major role in 17beta-estradiol-induced murine cholesterol gallstones

21 January 2018

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Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis

21 January 2018

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Sequence analysis of bile salt export pump (ABCB11) and multidrug resistance p-glycoprotein 3 (ABCB4, MDR3) in patients with intrahepatic cholestasis of pregnancy

21 January 2018

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Genetic evidence of heterogeneity in intrahepatic cholestasis of pregnancy

21 January 2018

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Targeted inactivation of sister of P-glycoprotein gene (spgp) in mice results in nonprogressive but persistent intrahepatic cholestasis

21 January 2018

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Tamoxifen in treatment of primary biliary cirrhosis

21 January 2018

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Tamoxifen: a novel treatment for primary biliary cirrhosis?

21 January 2018

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Prevention of cholesterol gallstone disease by FXR agonists in a mouse model.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M602723200

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30 July 2017

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