(Q34005458)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17667956%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

review article

1 reference

title

Modelling of the blood-brain barrier in drug discovery and development (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17667956%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

1 reference

1 reference

Vincent Berezowski

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17667956%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Stefan Lundquist

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17667956%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Maxime Culot

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17667956%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Mila Renftel

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17667956%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Marie-Pierre Dehouck

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17667956%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

publication date

1 August 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17667956%20AND%20SRC:MED&resulttype=core&format=json

Nature Reviews Drug Discovery

2 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17667956%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

volume

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17667956%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17667956%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

page(s)

650-661

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17667956%20AND%20SRC:MED&resulttype=core&format=json

Specialized localization of P-glycoprotein recognized by MRK 16 monoclonal antibody in endothelial cells of the brain and the spinal cord.

2 January 2020

cites work

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P-glycoprotein is strongly expressed in the luminal membranes of the endothelium of blood vessels in the brain

21 January 2018

1 reference

Subtractive expression cloning reveals high expression of CD46 at the blood-brain barrier

21 January 2018

1 reference

Blood-brain barrier tight junction disruption in human immunodeficiency virus-1 encephalitis

21 January 2018

1 reference

The blood-brain barrier: an overview: structure, regulation, and clinical implications

21 January 2018

1 reference

Molecular physiology and pathophysiology of tight junctions in the blood-brain barrier

31 March 2020

1 reference

Localization of drug-metabolizing enzyme activities to blood-brain interfaces and circumventricular organs.

31 March 2020

1 reference

Insulin effects on monovalent cation transport and Na-K-ATPase activity

31 March 2020

1 reference

Electron microscopy of the vascular bed of rat cerebral cortex.

31 March 2020

1 reference

Signaling at the gliovascular interface.

31 March 2020

1 reference

Food for thought: challenging the dogmas

31 March 2020

1 reference

New roles for astrocytes: Regulation of synaptic transmission

31 March 2020

1 reference

Enhanced expression of the blood-brain barrier GLUT1 glucose transporter gene by brain-derived factors

31 March 2020

1 reference

Signal transduction and glial cell modulation of cultured brain microvessel endothelial cell tight junctions.

31 March 2020

1 reference

F-actin cytoskeleton and sucrose permeability of immortalised rat brain microvascular endothelial cell monolayers: effects of cyclic AMP and astrocytic factors

31 March 2020

1 reference

Regulation of gamma-glutamyl transpeptidase and alkaline phosphatase activities in immortalized rat brain microvessel endothelial cells

31 March 2020

1 reference

Upregulation of the low density lipoprotein receptor at the blood-brain barrier: intercommunications between brain capillary endothelial cells and astrocytes

31 March 2020

1 reference

γ-Glutamyl Transpeptidase in Isolated Brain Endothelial Cells: Induction by Glial Cells in Vitro

31 March 2020

1 reference

Induction of blood-brain barrier properties in immortalized bovine brain endothelial cells by astrocytic factors

31 March 2020

1 reference

Astrocyte-endothelial interactions and blood-brain barrier permeability

31 March 2020

1 reference

In search of the astrocytic factor(s) modulating blood-brain barrier functions in brain capillary endothelial cells in vitro

31 March 2020

1 reference

Drug and gene targeting to the brain with molecular Trojan horses

31 March 2020

1 reference

Drug delivery to brain via the blood-brain barrier

31 March 2020

1 reference

High transcytosis of melanotransferrin (P97) across the blood-brain barrier

31 March 2020

1 reference

The blood-brain barrier transmigrating single domain antibody: mechanisms of transport and antigenic epitopes in human brain endothelial cells

31 March 2020

1 reference

Tissue-type plasminogen activator crosses the intact blood-brain barrier by low-density lipoprotein receptor-related protein-mediated transcytosis

31 March 2020

1 reference

Inhibition of NADPH oxidase attenuates vasospasm after experimental subarachnoid hemorrhage in rats

31 March 2020

1 reference

Recombinant Desmodus rotundus salivary plasminogen activator crosses the blood-brain barrier through a low-density lipoprotein receptor-related protein-dependent mechanism without exerting neurotoxic effects

31 March 2020

1 reference

Intercommunications between brain capillary endothelial cells and glial cells increase the transcellular permeability of the blood-brain barrier during ischaemia.

31 March 2020

1 reference

Electron microscopy of the blood-brain barrier in disease

31 March 2020

1 reference

Vascular permeability alterations to horseradish peroxidase in experimental brain injury

31 March 2020

1 reference

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

31 March 2020

1 reference

The physiological function of drug-transporting P-glycoproteins

31 March 2020

1 reference

Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview.

31 March 2020

1 reference

Plasma membrane localization of multidrug resistance-associated protein homologs in brain capillary endothelial cells

31 March 2020

1 reference

Differential, strain-specific cellular and subcellular distribution of multidrug transporters in murine choroid plexus and blood-brain barrier.

31 March 2020

1 reference

P-glycoprotein as the drug efflux pump in primary cultured bovine brain capillary endothelial cells

31 March 2020

1 reference

Cellular localization of P-glycoprotein in brain versus gonadal capillaries

31 March 2020

1 reference

Expression and function of multidrug resistance transporters at the blood-brain barriers

31 March 2020

1 reference

Multidrug resistance-associated proteins: expression and function in the central nervous system

31 March 2020

1 reference

Multidrug resistance-related transport proteins in isolated human brain microvessels and in cells cultured from these isolates.

31 March 2020

1 reference

Interactions of HIV protease inhibitors with ATP-dependent drug export proteins

31 March 2020

1 reference

Kinetic and biochemical analysis of carrier-mediated efflux of drugs through the blood-brain and blood-cerebrospinal fluid barriers: importance in the drug delivery to the brain

31 March 2020

1 reference

Inhibition of P-glycoprotein: rapid assessment of its implication in blood-brain barrier integrity and drug transport to the brain by an in vitro model of the blood-brain barrier.

31 March 2020

1 reference

Contribution of glial cells and pericytes to the mRNA profiles of P-glycoprotein and multidrug resistance-associated proteins in an in vitro model of the blood-brain barrier.

31 March 2020

1 reference

A family of drug transporters: the multidrug resistance-associated proteins.

31 March 2020

1 reference

Blood-brain barrier active efflux transporters: ATP-binding cassette gene family

31 March 2020

1 reference

Basolateral localization and export activity of the human multidrug resistance-associated protein in polarized pig kidney cells

31 March 2020

1 reference

Active efflux across the blood-brain barrier: role of the solute carrier family

31 March 2020

1 reference

Characterisation of the brain multidrug resistance protein (BMDP/ABCG2/BCRP) expressed at the blood–brain barrier

31 March 2020

1 reference

Prediction of blood-brain barrier permeation in drug discovery from in vivo, in vitro and in silico models

31 March 2020

1 reference

The role of blood-brain barrier studies in the pharmaceutical industry

31 March 2020

1 reference

The blood-brain barrier in vitro: Ten years of research on microvessels isolated from the brain

31 March 2020

1 reference

Blood-brain barrier-specific properties of a human adult brain endothelial cell line

31 March 2020

1 reference

GSH transport in human cerebrovascular endothelial cells and human astrocytes: evidence for luminal localization of Na+-dependent GSH transport in HCEC.

31 March 2020

1 reference

Compartmentalized coculture of rat brain endothelial cells and astrocytes: a syngenic model to study the blood-brain barrier

31 March 2020

1 reference

A functional in vitro model of rat blood-brain barrier for molecular analysis of efflux transporters

31 March 2020

1 reference

Bovine brain endothelial cells express tight junctions and monoamine oxidase activity in long-term culture.

31 March 2020

1 reference

An easier, reproducible, and mass-production method to study the blood-brain barrier in vitro.

31 March 2020

1 reference

In vitro model for evaluating drug transport across the blood-brain barrier

31 March 2020

1 reference

A cell culture model of the blood-brain barrier

31 March 2020

1 reference

Cerebral microvascular endothelial cell Na-K-Cl cotransport: regulation by astrocyte-conditioned medium

31 March 2020

1 reference

Properties of an immortalised vascular endothelial/glioma cell co-culture model of the blood-brain barrier

31 March 2020

1 reference

Induction of blood-brain barrier properties in cultured brain capillary endothelial cells: comparison between primary glial cells and C6 cell line

31 March 2020

1 reference

Hydrocortisone reinforces the blood-brain properties in a serum free cell culture system

31 March 2020

1 reference

An improved low-permeability in vitro-model of the blood-brain barrier: transport studies on retinoids, sucrose, haloperidol, caffeine and mannitol

31 March 2020

1 reference

Porcine brain microvessel endothelial cells as an in vitro model to predict in vivo blood-brain barrier permeability

31 March 2020

1 reference

Protective effect of glial cells against lipopolysaccharide-mediated blood-brain barrier injury

31 March 2020

1 reference

Rat brain endothelial cell lines for the study of blood-brain barrier permeability and transport functions

31 March 2020

1 reference

Occludin as direct target for glucocorticoid-induced improvement of blood-brain barrier properties in a murine in vitro system.

31 March 2020

1 reference

Evaluation of an in vitro coculture model for the blood-brain barrier: comparison of human umbilical vein endothelial cells (ECV304) and rat glioma cells (C6) from two commercial sources

31 March 2020

1 reference

Endothelial cell-cell junctions: happy together

31 March 2020

1 reference

Molecular anatomy of intercellular junctions in brain endothelial and epithelial barriers: electron microscopist's view

31 March 2020

1 reference

Prediction of drug transport through the blood-brain barrier in vivo: a comparison between two in vitro cell models.

31 March 2020

1 reference

Gene and protein expression profiling of human cerebral endothelial cells activated with tumor necrosis factor-alpha

31 March 2020

1 reference

Vascular genomics of the human brain

31 March 2020

1 reference

Blood—Brain Barrier Genomics

31 March 2020

1 reference

Vascular proteomics and subtractive antibody expression cloning

31 March 2020

1 reference

The Ro52/SS-A autoantigen has elevated expression at the brain microvasculature

31 March 2020

1 reference

Morphological and functional characterization of an in vitro blood-brain barrier model

31 March 2020

1 reference

Development of a humanized in vitro blood-brain barrier model to screen for brain penetration of antiepileptic drugs

31 March 2020

1 reference

Neurobarrier coupling in the brain: a partner of neurovascular and neurometabolic coupling?

31 March 2020

1 reference

Transport screening of drug cocktails through an in vitro blood-brain barrier: is it a good strategy for increasing the throughput of the discovery pipeline?

31 March 2020

1 reference

A new function for the LDL receptor: transcytosis of LDL across the blood-brain barrier

31 March 2020

1 reference

Transcellular transport as a mechanism of blood-brain barrier disruption during stroke.

31 March 2020

1 reference

Hypoxia-induced astrocytic reaction and increased vascular permeability in the rat cerebellum

31 March 2020

1 reference

Targeted delivery of proteins across the blood-brain barrier

31 March 2020

1 reference

The rat blood-brain barrier transcriptome

31 March 2020

1 reference

beta-amyloid-induced migration of monocytes across human brain endothelial cells involves RAGE and PECAM-1.

31 March 2020

1 reference

Permeability of proteins at the blood-brain barrier in the normal adult mouse and double transgenic mouse model of Alzheimer's disease.

31 March 2020

1 reference

Atherosclerosis and neurodegeneration: unexpected conspirators in Alzheimer's dementia.

31 March 2020

1 reference

beta-Amyloid-mediated vasoactivity and vascular endothelial damage.

31 March 2020

1 reference

Vasoactive effects of A beta in isolated human cerebrovessels and in a transgenic mouse model of Alzheimer's disease: role of inflammation

31 March 2020

1 reference

SOD1 rescues cerebral endothelial dysfunction in mice overexpressing amyloid precursor protein

31 March 2020

1 reference

Brain to plasma amyloid-beta efflux: a measure of brain amyloid burden in a mouse model of Alzheimer's disease

31 March 2020

1 reference

Blood-brain barrier disruption in multiple sclerosis

31 March 2020

1 reference

Interferon-beta prevents cytokine-induced neutrophil infiltration and attenuates blood-brain barrier disruption.

31 March 2020

1 reference

Blood-brain barrier breakdown in septic encephalopathy and brain tumours

31 March 2020

1 reference

Mechanisms, challenges and opportunities in stroke

31 March 2020

1 reference

Early appearance of activated matrix metalloproteinase-9 after focal cerebral ischemia in mice: a possible role in blood-brain barrier dysfunction

31 March 2020

1 reference

Inflammatory pain alters blood-brain barrier permeability and tight junctional protein expression.

31 March 2020

1 reference

Differentiating embryonic neural progenitor cells induce blood-brain barrier properties

31 March 2020

1 reference