(Q34007289)

30 July 2017

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title

Discovering small molecules to control stem cell fate (English)

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30 July 2017

1

Paul D Andrews

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30 July 2017

1 September 2011

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Future Medicinal Chemistry

30 July 2017

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30 July 2017

3

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30 July 2017

12

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30 July 2017

1539-1549

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Stem cell states, fates, and the rules of attraction

30 July 2017

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A chemical approach to stem-cell biology and regenerative medicine

21 January 2018

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Induced pluripotent stem cells as a model for accelerated patient- and disease-specific drug discovery.

21 January 2018

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Characterization of human embryonic stem cell lines by the International Stem Cell Initiative

21 January 2018

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Progressive accumulation of epigenetic heterogeneity during human ES cell culture

21 January 2018

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A ROCK inhibitor permits survival of dissociated human embryonic stem cells

21 January 2018

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High-content screening of feeder-free human embryonic stem cells to identify pro-survival small molecules

21 January 2018

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Novel regulators of stem cell fates identified by a multivariate phenotype screen of small compounds on human embryonic stem cell colonies

21 January 2018

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Revealing a core signaling regulatory mechanism for pluripotent stem cell survival and self-renewal by small molecules

21 January 2018

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ROCK inhibition enhances the recovery and growth of cryopreserved human embryonic stem cells and human induced pluripotent stem cells.

21 January 2018

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Naive and primed pluripotent states

21 January 2018

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Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs

21 January 2018

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A murine ESC-like state facilitates transgenesis and homologous recombination in human pluripotent stem cells.

21 January 2018

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The ground state of embryonic stem cell self-renewal

21 January 2018

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Self-renewal of embryonic stem cells by a small molecule

21 January 2018

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Small-molecule synergist of the Wnt/beta-catenin signaling pathway

21 January 2018

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Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor

21 January 2018

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Synthetic small molecules that control stem cell fate

21 January 2018

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Wnt/beta-catenin/CBP signaling maintains long-term murine embryonic stem cell pluripotency

21 January 2018

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Directed embryonic stem cell differentiation with small molecules

21 January 2018

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Small molecules that modulate embryonic stem cell fate and somatic cell reprogramming

21 January 2018

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Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism

21 January 2018

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Dorsomorphin, a selective small molecule inhibitor of BMP signaling, promotes cardiomyogenesis in embryonic stem cells

21 January 2018

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Structure-activity relationship study of bone morphogenetic protein (BMP) signaling inhibitors

21 January 2018

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In vivo structure-activity relationship study of dorsomorphin analogues identifies selective VEGF and BMP inhibitors.

21 January 2018

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Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

21 January 2018

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High-efficiency induction of neural conversion in human ESCs and human induced pluripotent stem cells with a single chemical inhibitor of transforming growth factor beta superfamily receptors

21 January 2018

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A small molecule primes embryonic stem cells for differentiation

21 January 2018

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Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells

21 January 2018

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A small molecule that directs differentiation of human ESCs into the pancreatic lineage.

21 January 2018

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Progress toward the clinical application of patient-specific pluripotent stem cells

21 January 2018

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Technical challenges in using human induced pluripotent stem cells to model disease

21 January 2018

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A chemical platform for improved induction of human iPSCs

21 January 2018

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Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds

21 January 2018

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Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2

21 January 2018

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A small-molecule inhibitor of tgf-Beta signaling replaces sox2 in reprogramming by inducing nanog

21 January 2018

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Tgfbeta signal inhibition cooperates in the induction of iPSCs and replaces Sox2 and cMyc

21 January 2018

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Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4.

21 January 2018

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Dedifferentiation of lineage-committed cells by a small molecule

21 January 2018

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Reversine-treated fibroblasts acquire myogenic competence in vitro and in regenerating skeletal muscle.

21 January 2018

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Reversine increases the plasticity of lineage-committed mammalian cells

21 January 2018

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Reversine increases the plasticity of lineage-committed cells toward neuroectodermal lineage

21 January 2018

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Reversine, a novel Aurora kinases inhibitor, inhibits colony formation of human acute myeloid leukemia cells

21 January 2018

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The Aurora B kinase activity is required for the maintenance of the differentiated state of murine myoblasts.

21 January 2018

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21 January 2018

Identifiers

DOI

10.4155/FMC.11.98

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30 July 2017

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PubMed ID

21882946