(Q34008771)

English

HIV-1 Nef induces proinflammatory state in macrophages through its acidic cluster domain: involvement of TNF alpha receptor associated factor 2.

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12 February 2020

HIV-1 Nef induces proinflammatory state in macrophages through its acidic cluster domain: involvement of TNF alpha receptor associated factor 2 (English)

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12 February 2020

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Giorgio Mangino

1

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12 February 2020

Gabriele Vaccari

4

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12 February 2020

Filippo Acconcia

5

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12 February 2020

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12 February 2020

13

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12 February 2020

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Zulema A Percario

2

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12 February 2020

Gianna Fiorucci

3

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12 February 2020

Cristiano Chiarabelli

6

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12 February 2020

Stefano Leone

7

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12 February 2020

Alessia Noto

8

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12 February 2020

Florian A Horenkamp

9

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12 February 2020

Santiago Manrique

10

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12 February 2020

Fabio Polticelli

12

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12 February 2020

Elisabetta Affabris

14

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12 February 2020

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23 August 2011

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12 February 2020

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12 February 2020

6

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12 February 2020

8

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12 February 2020

e22982

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12 February 2020

copyright license

Creative Commons Attribution 4.0 International

23 August 2011

1 reference

April 2022 Public Data File from Crossref

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describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3160284/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Conformation of the dileucine-based sorting motif in HIV-1 Nef revealed by intermolecular domain assembly

1 reference

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HIV-1 evades virus-specific IgG2 and IgA responses by targeting systemic and intestinal B cells via long-range intercellular conduits

1 reference

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5 July 2018

Functional characterization of the human immunodeficiency virus type 1 Nef acidic domain

1 reference

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5 July 2018

TRAF6 distinctively mediates MyD88- and IRAK-1-induced activation of NF-kappaB.

2 references

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5 July 2018

https://pubmed.ncbi.nlm.nih.gov/21886773

12 December 2020

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Herpesvirus saimiri STP-A oncoprotein utilizes Src family protein tyrosine kinase and tumor necrosis factor receptor-associated factors to elicit cellular signal transduction

1 reference

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5 July 2018

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1 reference

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5 July 2018

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1 reference

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5 July 2018

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1 reference

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5 July 2018

Pathogen recognition with Toll-like receptors

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1 reference

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5 July 2018

1Hepatitis C virus NS5A protein modulates c-Jun N-terminal kinase through interaction with tumor necrosis factor receptor-associated factor 2.

1 reference

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5 July 2018

HIV-1 Nef downregulates MHC-I by a PACS-1- and PI3K-regulated ARF6 endocytic pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3160284

5 July 2018

Distinct molecular mechanism for initiating TRAF6 signalling

1 reference

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5 July 2018

Macrophages and HIV infection: therapeutical approaches toward this strategic virus reservoir

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3160284

5 July 2018

Structure--function relationships in HIV-1 Nef.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3160284

5 July 2018

The alpha and beta subunits of IkappaB kinase (IKK) mediate TRAF2-dependent IKK recruitment to tumor necrosis factor (TNF) receptor 1 in response to TNF

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3160284

5 July 2018

The nuclear factor-kappaB engages CBP/p300 and histone acetyltransferase activity for transcriptional activation of the interleukin-6 gene promoter.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3160284

5 July 2018

The structural basis for the recognition of diverse receptor sequences by TRAF2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3160284

5 July 2018

HIV-1 Nef mediates lymphocyte chemotaxis and activation by infected macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3160284

5 July 2018

In vivo monocyte tropism of pathogenic feline immunodeficiency viruses

1 reference

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5 July 2018

Sequence variations in human immunodeficiency virus type 1 Nef are associated with different stages of disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3160284

5 July 2018

TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3160284

5 July 2018

Specificities of CD40 signaling: involvement of TRAF2 in CD40-induced NF-kappaB activation and intercellular adhesion molecule-1 up-regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3160284

5 July 2018

Tumor necrosis factor receptor-associated factor 6 (TRAF6) stimulates extracellular signal-regulated kinase (ERK) activity in CD40 signaling along a ras-independent pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3160284

5 July 2018

Characterization of LMP-1's association with TRAF1, TRAF2, and TRAF3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3160284

5 July 2018

Deletion of nef slows but does not prevent CD4-positive T-cell depletion in human immunodeficiency virus type 1-infected human-PBL-SCID mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3160284

5 July 2018

Identification of TRAF6, a novel tumor necrosis factor receptor-associated factor protein that mediates signaling from an amino-terminal domain of the CD40 cytoplasmic region

1 reference

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5 July 2018

Soluble Nef antigen of HIV-1 is cytotoxic for human CD4+ T cells

1 reference

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5 July 2018

Genomic cloning and promoter analysis of macrophage inflammatory protein (MIP)-2, MIP-1 alpha, and MIP-1 beta, members of the chemokine superfamily of proinflammatory cytokines.

1 reference

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5 July 2018

Genotypic and phenotypic characterization of HIV-1 patients with primary infection

1 reference

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5 July 2018

Analysis of human immunodeficiency virus type 1 nef gene sequences present in vivo

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Importance of the nef gene for maintenance of high virus loads and for development of AIDS

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Lymphoid organs function as major reservoirs for human immunodeficiency virus

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5 July 2018

HIV-1 Nef intersects the macrophage CD40L signalling pathway to promote resting-cell infection

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0022982

21 January 2018

HIV-1 Nef induces the release of inflammatory factors from human monocyte/macrophages: involvement of Nef endocytotic signals and NF-kappa B activation

1 reference

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21 January 2018

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1 reference

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21 January 2018

Human immunodeficiency virus type 1 (HIV-1) Nef activates STAT3 in primary human monocyte/macrophages through the release of soluble factors: involvement of Nef domains interacting with the cell endocytotic machinery

1 reference

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21 January 2018

HIV-1 Nef triggers Vav-mediated signaling pathway leading to functional and morphological differentiation of dendritic cells

1 reference

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21 January 2018

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1 reference

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21 January 2018

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1 reference

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1 reference

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/21886773

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative quantification of IL-1beta, IL-10, IL-10r, TNFalpha and IL-7 mRNA levels in UV-irradiated human skin in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/21886773

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 Nef activates STAT1 in human monocytes/macrophages through the release of soluble factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/21886773

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21886773

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD40 ligation stimulates MCP-1 and IL-8 production, TRAF6 recruitment, and MAPK activation in proximal tubule cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21886773

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21886773

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0022982

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21886773%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

2011PLoSO...622982M

0 references

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21886773%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21886773%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

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