(Q27667185)

5

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Kalle Saksela

6

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Sebastian Lülf

4

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author name string

Florian A Horenkamp

1

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Sebastian Breuer

2

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Antje Schulte

3

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Matthias Geyer

Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients

7

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publication date

July 2011

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published in

Traffic

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volume

12

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issue

7

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page(s)

867-77

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cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

Pathogenicity and immunogenicity of attenuated, nef-deleted HIV-1 strains in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

Importance of the nef gene for maintenance of high virus loads and for development of AIDS

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

Structure--function relationships in HIV-1 Nef.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

Role of Nef in primate lentiviral immunopathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

Human immunodeficiency virus type 1 Nef: adapting to intracellular trafficking pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

Interaction of HIV-1 Nef with the cellular dileucine-based sorting pathway is required for CD4 down-regulation and optimal viral infectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

HIV-1 Nef downregulates MHC-I by a PACS-1- and PI3K-regulated ARF6 endocytic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

The SH3 domain-binding surface and an acidic motif in HIV-1 Nef regulate trafficking of class I MHC complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

HIV-1 Nef-induced down-regulation of MHC class I requires AP-1 and clathrin but not PACS-1 and is impeded by AP-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

HIV-1 Nef disrupts MHC-I trafficking by recruiting AP-1 to the MHC-I cytoplasmic tail

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

Identification of the Nef-associated kinase as p21-activated kinase 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

Activation of Vav by Nef induces cytoskeletal rearrangements and downstream effector functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

Interactions of HIV-1 NEF with cellular signal transducing proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

Role of myristoylation and N-terminal basic residues in membrane association of the human immunodeficiency virus type 1 Nef protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

HIV-1 Nef membrane association depends on charge, curvature, composition and sequence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

Specific and distinct determinants mediate membrane binding and lipid raft incorporation of HIV-1(SF2) Nef.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

Refined solution structure and backbone dynamics of HIV-1 Nef.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

The crystal structure of HIV-1 Nef protein bound to the Fyn kinase SH3 domain suggests a role for this complex in altered T cell receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

Structure of the anchor-domain of myristoylated and non-myristoylated HIV-1 Nef protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

21 January 2018

Nef--an adaptor adaptor?

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

Functional characterization of HIV-1 Nef mutants in the context of viral infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

SH3 domains with high affinity and engineered ligand specificities targeted to HIV-1 Nef.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

RT loop flexibility enhances the specificity of Src family SH3 domains for HIV-1 Nef

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

How SH3 domains recognize proline

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

Exploiting the basis of proline recognition by SH3 and WW domains: design of N-substituted inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

A natural variability in the proline-rich motif of Nef modulates HIV-1 replication in primary T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

Biochemical indication for myristoylation-dependent conformational changes in HIV-1 Nef.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

Adaptors for clathrin-mediated traffic

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

Interactions between HIV1 Nef and vacuolar ATPase facilitate the internalization of CD4

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

Subunit H of the V-ATPase binds to the medium chain of adaptor protein complex 2 and connects Nef to the endocytic machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

Nef-induced CD4 downregulation: a diacidic sequence in human immunodeficiency virus type 1 Nef does not function as a protein sorting motif through direct binding to beta-COP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

A diacidic motif in human immunodeficiency virus type 1 Nef is a novel determinant of binding to AP-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

Nef-induced CD4 degradation: a diacidic-based motif in Nef functions as a lysosomal targeting signal through the binding of beta-COP in endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

HIV-1 Nef targets MHC-I and CD4 for degradation via a final common beta-COP-dependent pathway in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

Cluster of differentiation antigen 4 (CD4) endocytosis and adaptor complex binding require activation of the CD4 endocytosis signal by serine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

Leucine-based receptor sorting motifs are dependent on the spacing relative to the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

Modulation of cellular protein trafficking by human immunodeficiency virus type 1 Nef: role of the acidic residue in the ExxxLL motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

A structural explanation for the binding of endocytic dileucine motifs by the AP2 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

A basic patch on alpha-adaptin is required for binding of human immunodeficiency virus type 1 Nef and cooperative assembly of a CD4-Nef-AP-2 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

The CD4 determinant for downregulation by HIV-1 Nef directly binds to Nef. Mapping of the Nef binding surface by NMR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

The structural era of endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

Molecular model for a complete clathrin lattice from electron cryomicroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

Characterization and molecular basis of the oligomeric structure of HIV-1 nef protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

Self-association of the Lentivirus protein, Nef

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

HIV-1 Nef dimerization is required for Nef-mediated receptor downregulation and viral replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

Inhibition of cellular functions of HIV-1 Nef by artificial SH3 domains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

Phasercrystallographic software

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

Coot: model-building tools for molecular graphics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X

Refinement of macromolecular structures by the maximum-likelihood method

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01205.X