(Q34021511)

30 July 2017

Amyloid-beta aggregates cause alterations of astrocytic metabolic phenotype: impact on neuronal viability (English)

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30 July 2017

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1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6634099&resulttype=core&format=json

15 May 2020

Pierre Magistretti

7

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6634099&resulttype=core&format=json

15 May 2020

author name string

Mathilde Gavillet

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6634099&resulttype=core&format=json

15 May 2020

Mireille Bélanger

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6634099&resulttype=core&format=json

15 May 2020

Thierry Laroche

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6634099&resulttype=core&format=json

15 May 2020

David Viertl

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6634099&resulttype=core&format=json

15 May 2020

Hilal A Lashuel

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6634099&resulttype=core&format=json

15 May 2020

language of work or name

English

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publication date

1 March 2010

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30 July 2017

Journal of Neuroscience

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6634099&resulttype=core&format=json

15 May 2020

volume

30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6634099&resulttype=core&format=json

15 May 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6634099&resulttype=core&format=json

15 May 2020

page(s)

3326-3338

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6634099&resulttype=core&format=json

Occurrence of the diffuse amyloid beta-protein (Abeta) deposits with numerous Abeta-containing glial cells in the cerebral cortex of patients with Alzheimer's disease.

15 May 2020

cites work

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12 December 2020

The glutathione system of peroxide detoxification is less efficient in neurons than in astroglial cells.

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12 December 2020

L-Glutamate and insulin enhance glycogen synthesis in cultured astrocytes from the rat brain through different intracellular mechanisms.

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12 December 2020

Activities of key glycolytic enzymes in the brains of patients with Alzheimer's disease.

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12 December 2020

Amyloid beta-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates

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12 December 2020

Uptake, degradation, and release of fibrillar and soluble forms of Alzheimer's amyloid beta-peptide by microglial cells.

1 reference

12 December 2020

Functional brain imaging in the resting state and during activation in Alzheimer's disease. Implications for disease mechanisms involving oxidative phosphorylation

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12 December 2020

Inherent abnormalities in energy metabolism in Alzheimer disease. Interaction with cerebrovascular compromise

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12 December 2020

The role of oxidative stress in the toxicity induced by amyloid beta-peptide in Alzheimer's disease

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12 December 2020

Metabolism and functions of glutathione in brain.

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12 December 2020

Apolipoprotein E receptors mediate the effects of beta-amyloid on astrocyte cultures

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12 December 2020

Glycogen is mobilized during the disposal of peroxides by cultured astroglial cells from rat brain

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12 December 2020

Ligands of macrophage scavenger receptor induce cytokine expression via differential modulation of protein kinase signaling pathways

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12 December 2020

Insulin signalling and the regulation of glucose and lipid metabolism

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12 December 2020

Lactate reduces glutamate-induced neurotoxicity in rat cortex

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12 December 2020

Brain metabolism and brain disease: is metabolic deficiency the proximate cause of Alzheimer dementia?

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12 December 2020

Interactions of oxidative stress with cellular calcium dynamics and glucose metabolism in Alzheimer's disease

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12 December 2020

Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability.

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12 December 2020

Long-term modulation of glucose utilization by IL-1 alpha and TNF-alpha in astrocytes: Na+ pump activity as a potential target via distinct signaling mechanisms

1 reference

12 December 2020

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

1 reference

12 December 2020

Scavenger receptors in neurobiology and neuropathology: their role on microglia and other cells of the nervous system

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12 December 2020

Microglia and inflammatory mechanisms in the clearance of amyloid beta peptide

1 reference

12 December 2020

In vivo conversion of racemized beta-amyloid ([D-Ser 26]A beta 1-40) to truncated and toxic fragments ([D-Ser 26]A beta 25-35/40) and fragment presence in the brains of Alzheimer's patients

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12 December 2020

In vitro characterization of conditions for amyloid-beta peptide oligomerization and fibrillogenesis

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12 December 2020

Cortical glucose metabolism is altered in aged transgenic Tg2576 mice that demonstrate Alzheimer plaque pathology

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12 December 2020

Adult mouse astrocytes degrade amyloid-beta in vitro and in situ

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12 December 2020

Beta-amyloid racemized at the Ser26 residue in the brains of patients with Alzheimer disease: implications in the pathogenesis of Alzheimer disease

1 reference

12 December 2020

A meta-analysis of structural and functional brain imaging in dementia of the Alzheimer's type: a neuroimaging profile

1 reference

12 December 2020

1 reference

12 December 2020

Astrocytes accumulate Aβ42 and give rise to astrocytic amyloid plaques in Alzheimer disease brains

1 reference

12 December 2020

The regulation of glucose metabolism by HIF-1 mediates a neuroprotective response to amyloid beta peptide

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12 December 2020

Beta-amyloid peptides induce mitochondrial dysfunction and oxidative stress in astrocytes and death of neurons through activation of NADPH oxidase.

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12 December 2020

Glucocorticoids modulate neurotransmitter-induced glycogen metabolism in cultured cortical astrocytes.

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12 December 2020

Arsenite induces HIF-1a and VEGF through PI3K, Akt and reactive oxygen species in DU145 human prostate carcinoma cells

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12 December 2020

Toxicity of amyloid beta peptide: tales of calcium, mitochondria, and oxidative stress

1 reference

12 December 2020

Synaptophysin: leading actor or walk-on role in synaptic vesicle exocytosis?

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12 December 2020

Alzheimer disease: mechanistic understanding predicts novel therapies

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12 December 2020

Amyloid beta-peptide interactions with neuronal and glial cell plasma membrane: binding sites and implications for Alzheimer's disease

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12 December 2020

Contribution of glial cells to the development of amyloid plaques in Alzheimer's disease

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12 December 2020

Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid-beta peptides

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12 December 2020

Differential effects of oligomeric and fibrillar amyloid-beta 1-42 on astrocyte-mediated inflammation.

1 reference

12 December 2020

Biochemistry and cell biology of mammalian scavenger receptors.

1 reference

12 December 2020

Lactate: the ultimate cerebral oxidative energy substrate?

1 reference

12 December 2020

Expression of scavenger receptors in glial cells. Comparing the adhesion of astrocytes and microglia from neonatal rats to surface-bound beta-amyloid

1 reference

12 December 2020

Neuron-glia metabolic coupling and plasticity

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12 December 2020

The glutamate/GABA-glutamine cycle: aspects of transport, neurotransmitter homeostasis and ammonia transfer.

1 reference

12 December 2020

Possible role of scavenger receptor SRCL in the clearance of amyloid-beta in Alzheimer's disease.

1 reference

12 December 2020

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

1 reference

12 December 2020

Macrophage scavenger receptors and host-derived ligands

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12 December 2020

Transplanted astrocytes internalize deposited beta-amyloid peptides in a transgenic mouse model of Alzheimer's disease.

1 reference

12 December 2020

Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons

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12 December 2020

Modulation of astrocytic metabolic phenotype by proinflammatory cytokines

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12 December 2020

Dietary flavonoid (-)epicatechin stimulates phosphatidylinositol 3-kinase-dependent anti-oxidant response element activity and up-regulates glutathione in cortical astrocytes.

1 reference

12 December 2020

A comparative study of beta-amyloid peptides Abeta1-42 and Abeta25-35 toxicity in organotypic hippocampal slice cultures

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12 December 2020

The mystery and magic of glia: a perspective on their roles in health and disease

1 reference

12 December 2020

Astroglia in dementia and Alzheimer's disease.

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12 December 2020

Brain glucose hypometabolism and oxidative stress in preclinical Alzheimer's disease

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12 December 2020

The induction of HIF-1 reduces astrocyte activation by amyloid beta peptide

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12 December 2020

The role of astroglia in neuroprotection

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12 December 2020

Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

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12 December 2020

Lactate-Supported Synaptic Function in the Rat Hippocampal Slice Preparation

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12 December 2020

Mechanism of dye response and interference in the Bradford protein assay

1 reference

12 December 2020

Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease

1 reference

12 December 2020

Oxidative stress in the central nervous system: monitoring the metabolic response using the pentose phosphate pathway

1 reference

12 December 2020

Structure-activity analyses of beta-amyloid peptides: contributions of the beta 25-35 region to aggregation and neurotoxicity

1 reference

12 December 2020

Amyloid-beta aggregation: selective inhibition of aggregation in mixtures of amyloid with different chain lengths

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12 December 2020

Hydrogen peroxide mediates amyloid beta protein toxicity

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12 December 2020

Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state

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12 December 2020

Assessment of the role of the glutathione and pentose phosphate pathways in the protection of primary cerebrocortical cultures from oxidative stress

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12 December 2020

Scavenger receptor-mediated adhesion of microglia to beta-amyloid fibrils

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12 December 2020

Changes of activity and isozyme pattern of phosphofructokinase in the brains of patients with Alzheimer's disease.

1 reference

12 December 2020

Amyloid beta-peptide impairs glucose transport in hippocampal and cortical neurons: involvement of membrane lipid peroxidation

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12 December 2020

Preferential adsorption, internalization and resistance to degradation of the major isoform of the Alzheimer's amyloid peptide, A beta 1-42, in differentiated PC12 cells

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12 December 2020

The inhibitory effects of beta-amyloid on glutamate and glucose uptakes by cultured astrocytes.

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12 December 2020

Endogenous monocarboxylates sustain hippocampal synaptic function and morphological integrity during energy deprivation.

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12 December 2020

The role of A beta 42 in Alzheimer's disease

1 reference

12 December 2020

10.1523/JNEUROSCI.5098-09.2010

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6634099&resulttype=core&format=json

15 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6634099&resulttype=core&format=json

15 May 2020

1 reference