(Q34024395)

30 July 2017

title

Deficiency in B7-H1 (PD-L1)/PD-1 coinhibition triggers pancreatic beta-cell destruction by insulin-specific, murine CD8 T-cells (English)

1 reference

30 July 2017

1 reference

1

Tarvo Rajasalu

0 references

author name string

Tarvo Rajasalu

1

1 reference

30 July 2017

Helen Brosi

2

1 reference

30 July 2017

Cornelia Schuster

3

1 reference

30 July 2017

Andreas Spyrantis

4

1 reference

30 July 2017

Bernhard Otto Boehm

5

1 reference

30 July 2017

Lieping Chen

6

1 reference

30 July 2017

Jörg Reimann

7

1 reference

30 July 2017

Reinhold Schirmbeck

8

1 reference

30 July 2017

language of work or name

English

0 references

publication date

18 May 2010

1 reference

30 July 2017

1 reference

30 July 2017

volume

59

1 reference

30 July 2017

issue

8

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30 July 2017

page(s)

1966-1973

1 reference

Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

30 July 2017

copyright license

start time

27 August 2021

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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1 reference

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Molecular targeting of islet autoantigens

5 July 2018

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The long and winding road to understanding and conquering type 1 diabetes

5 July 2018

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T cell islet accumulation in type 1 diabetes is a tightly regulated, cell-autonomous event

5 July 2018

1 reference

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Animal models of human type 1 diabetes.

5 July 2018

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Can we learn from viruses how to prevent type 1 diabetes?: the role of viral infections in the pathogenesis of type 1 diabetes and the development of novel combination therapies

5 July 2018

1 reference

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CTLs are targeted to kill beta cells in patients with type 1 diabetes through recognition of a glucose-regulated preproinsulin epitope

5 July 2018

1 reference

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Blockade of PD-1/B7-H1 interaction restores effector CD8+ T cell responses in a hepatitis C virus core murine model

5 July 2018

1 reference

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Human CD8 responses to a complete epitope set from preproinsulin: implications for approaches to epitope discovery.

5 July 2018

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Insulin as an autoantigen in NOD/human diabetes

5 July 2018

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PD-1 and its ligands in tolerance and immunity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911076

Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responses

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911076

PD-1 and PD-1 ligands: from discovery to clinical application

5 July 2018

1 reference

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Atomic structures of amyloid cross-beta spines reveal varied steric zippers

5 July 2018

1 reference

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The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection

5 July 2018

1 reference

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Cutting Edge: Programmed death (PD) ligand-1/PD-1 interaction is required for CD8+ T cell tolerance to tissue antigens

5 July 2018

1 reference

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Insulin-induced remission in new-onset NOD mice is maintained by the PD-1-PD-L1 pathway.

5 July 2018

1 reference

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Tissue expression of PD-L1 mediates peripheral T cell tolerance.

5 July 2018

1 reference

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The PD-1-PD-L pathway in immunological tolerance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911076

Autoreactive CD8 T cells associated with beta cell destruction in type 1 diabetes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911076

Recognition of a subregion of human proinsulin by class I-restricted T cells in type 1 diabetic patients

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911076

5 July 2018

The B7 family revisited

1 reference

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The NOD mouse: a model of immune dysregulation

5 July 2018

1 reference

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Co-inhibitory molecules of the B7-CD28 family in the control of T-cell immunity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911076

Local expression of B7-H1 promotes organ-specific autoimmunity and transplant rejection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911076

Insulin autoimmunity: prediction/precipitation/prevention type 1A diabetes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911076

The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911076

Making and breaking tolerance.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911076

Tolerance to islet autoantigens in type 1 diabetes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911076

DNA vaccines: a key for inducing long-term cellular immunity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911076

Bovine and human insulin activate CD8+-autoreactive CTL expressing both type 1 and type 2 cytokines in C57BL/6 mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911076

CD8 T cell ignorance or tolerance to islet antigens depends on antigen dose

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911076

Immunological studies on PD-1 deficient mice: implication of PD-1 as a negative regulator for B cell responses

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911076

Coexpression of B7-1 and viral ("self") transgenes in pancreatic beta cells can break peripheral ignorance and lead to spontaneous autoimmune diabetes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911076

Mice expressing both B7-1 and viral glycoprotein on pancreatic beta cells along with glycoprotein-specific transgenic T cells develop diabetes due to a breakdown of T-lymphocyte unresponsiveness

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911076

The diabetogenic, insulin-specific CD8 T cell response primed in the experimental autoimmune diabetes model in RIP-B7.1 mice.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911076

Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911076

B7-H1 determines accumulation and deletion of intrahepatic CD8(+) T lymphocytes.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911076

CD8+ T-cell responses identify beta-cell autoimmunity in human type 1 diabetes

29 October 2018

1 reference

12 December 2020

Induction of autoimmune diabetes through insulin (but not GAD65) DNA vaccination in nonobese diabetic and in RIP-B7.1 mice

1 reference

12 December 2020

Experimental autoimmune diabetes: a new tool to study mechanisms and consequences of insulin-specific autoimmunity

1 reference

12 December 2020

Mechanisms of PDL1-mediated regulation of autoimmune diabetes

1 reference

12 December 2020

Processing in the endoplasmic reticulum generates an epitope on the insulin A chain that stimulates diabetogenic CD8 T cell responses

1 reference

12 December 2020

Identifiers

DOI

10.2337/DB09-1135

1 reference

release_6shqyvdjqvdfff7vfgq4mm6eni

30 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/6shqyvdjqvdfff7vfgq4mm6eni

24 November 2022

mapped directly with Wikidata item

PMC publication ID

2911076

1 reference

30 July 2017

1 reference