(Q34031569)

30 July 2017

title

Synthetic genetic polymers capable of heredity and evolution (English)

1 reference

30 July 2017

Christopher Cozens

3

0 references

Marleen Renders

Marleen Renders

5

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Alexander I Taylor

Alexander I Taylor

2

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Vitor B Pinheiro

Vitor B Pinheiro

1

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Stephen H. McLaughlin

Stephen H McLaughlin

10

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Piet Herdewijn

Piet Herdewijn

11

0 references

Jesper Wengel

Jesper Wengel

8

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author name string

Mikhail Abramov

4

1 reference

30 July 2017

Su Zhang

6

1 reference

30 July 2017

John C Chaput

7

1 reference

30 July 2017

Sew-Yeu Peak-Chew

9

1 reference

30 July 2017

Philipp Holliger

12

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30 July 2017

language of work or name

English

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publication date

1 April 2012

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30 July 2017

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30 July 2017

volume

336

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30 July 2017

issue

6079

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30 July 2017

page(s)

341-344

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Chemical etiology of nucleic acid structure

30 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

Discovery, characterization, and optimization of an unnatural base pair for expansion of the genetic alphabet

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

DNA analogues with nonphosphodiester backbones.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

Chemical etiology of nucleic acid structure: the alpha-threofuranosyl-(3'-->2') oligonucleotide system

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

Nucleic acids with a six-membered 'carbohydrate' mimic in the backbone

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

Locked vs. unlocked nucleic acids (LNA vs. UNA): contrasting structures work towards common therapeutic goals

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

Survey and summary: The applications of universal DNA base analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

A method to select chemically modified aptamers directly

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

Efficient and rapid template-directed nucleic acid copying using 2'-amino-2',3'-dideoxyribonucleoside-5'-phosphorimidazolide monomers

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

An in vitro translation, selection and amplification system for peptide nucleic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

Direct in vitro selection of a 2'-O-methyl aptamer to VEGF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

Darwinian evolution of an alternative genetic system provides support for TNA as an RNA progenitor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

High fidelity TNA synthesis by Therminator polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

2'-Deoxy-2'-fluoro-beta-D-arabinonucleosides and oligonucleotides (2'F-ANA): synthesis and physicochemical studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

Synthesis and biophysical properties of arabinonucleic acids (ANA): circular dichroic spectra, melting temperatures, and ribonuclease H susceptibility of ANA.RNA hybrid duplexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

Structural basis for uracil recognition by archaeal family B DNA polymerases

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

Acyclic and dideoxy terminator preferences denote divergent sugar recognition by archaeon and Taq DNA polymerases

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

Evolutionarily conserved pathways of energetic connectivity in protein families

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

Biophysical characterization of DNA and RNA aptamer interactions with hen egg lysozyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

In vitro selection identifies key determinants for loop-loop interactions: RNA aptamers selective for the TAR RNA element of HIV-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

Enzymatic incorporation of LNA nucleotides into DNA strands.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

Synthesis of alpha-L-threofuranosyl nucleoside triphosphates (tNTPs).

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

Use of the tetracycline promoter for the tightly regulated production of a murine antibody fragment in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

CyDNA: synthesis and replication of highly Cy-dye substituted DNA by an evolved polymerase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

Structure of the replicating complex of a pol alpha family DNA polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

Crystal structure of a pol alpha family replication DNA polymerase from bacteriophage RB69

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

Crystal structure of a thermostable type B DNA polymerase from Thermococcus gorgonarius

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

BEAMing: single-molecule PCR on microparticles in water-in-oil emulsions

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

Crystal structure of Pfu, the high fidelity DNA polymerase from Pyrococcus furiosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

Building a replisome from interacting pieces: sliding clamp complexed to a peptide from DNA polymerase and a polymerase editing complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

Structural Insight into Translesion Synthesis by DNA Pol II

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

Crystal structure of the herpes simplex virus 1 DNA polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

Structural basis of high-fidelity DNA synthesis by yeast DNA polymerase delta

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

Insights into DNA replication: the crystal structure of DNA polymerase B1 from the archaeon Sulfolobus solfataricus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

Uracil recognition in archaeal DNA polymerases captured by X-ray crystallography

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

Advances and pitfalls of protein structural alignment

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

MUSCLE: a multiple sequence alignment method with reduced time and space complexity

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

Evolving a polymerase for hydrophobic base analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

Evolutionarily conserved networks of residues mediate allosteric communication in proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

Expanding the chemistry of DNA for in vitro selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

In vitro selection of RNA molecules that bind specific ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

Driving in vitro selection of anti-HIV-1 TAR aptamers by magnesium concentration and temperature

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

An enzyme-linked oligonucleotide assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

Interpretation of deviations from pseudo-first-order kinetic behavior in the characterization of ligand binding by biosensor technology

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

Man-made cell-like compartments for molecular evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

Mfold web server for nucleic acid folding and hybridization prediction

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

Hexitol nucleic acid-containing aptamers are efficient ligands of HIV-1 TAR RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

Aptamer-based sensor arrays for the detection and quantitation of proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

LNA/DNA chimeric oligomers mimic RNA aptamers targeted to the TAR RNA element of HIV-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

Polymerase engineering: towards the encoded synthesis of unnatural biopolymers

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1217622

21 January 2018

Identifiers

DOI

10.1126/SCIENCE.1217622

1 reference

30 July 2017

0 references

1 reference

30 July 2017

1 reference