(Q34033160)

30 July 2017

1 reference

title

HIV-1 Nef: a critical factor in viral-induced pathogenesis (English)

1 reference

30 July 2017

Greenway AL

1

1 reference

PubMed ID

10987095

30 July 2017

Holloway G

series ordinal

2

1 reference

PubMed ID

10987095

30 July 2017

McPhee DA

series ordinal

3

1 reference

30 July 2017

1 January 2000

1 reference

30 July 2017

Advances in Pharmacology

1 reference

30 July 2017

48

1 reference

30 July 2017

299-343

1 reference

Nef protein of HIV-1 is a transcriptional repressor of HIV-1 LTR

30 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Nef stimulates human immunodeficiency virus type 1 proviral DNA synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Replication and pathogenicity of human immunodeficiency virus type 1 accessory gene mutants in SCID-hu mice

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

The SCID-hu mouse as a model for HIV-1 infection

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

The crystal structure of HIV-1 Nef protein bound to the Fyn kinase SH3 domain suggests a role for this complex in altered T cell receptor signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Rev is necessary for translation but not cytoplasmic accumulation of HIV-1 vif, vpr, and env/vpu 2 RNAs

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Pathogenicity of live, attenuated SIV after mucosal infection of neonatal macaques

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Constitutive expression of human immunodeficiency virus (HIV) nef protein in human astrocytes does not influence basal or induced HIV long terminal repeat activity.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

The N-Terminus of Nef from HIV-1/SIV Associates with a Protein Complex Containing Lck and a Serine Kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

HIV-1 Nef leads to inhibition or activation of T cells depending on its intracellular localization

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Lipopolysaccharide-induced cytokine production in human monocytes: role of tyrosine phosphorylation in transmembrane signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Use of the two-hybrid system to identify cellular partners of the HIV1 Nef protein.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Downregulation of cell-surface CD4 expression by simian immunodeficiency virus Nef prevents viral super infection

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Induction of activator protein 1 (AP-1) in macrophages by human immunodeficiency virus type-1 NEF is a cell-type-specific response that requires both hck and MAPK signaling events

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

In vitro replication kinetics of human immunodeficiency virus type 1 (HIV-1) variants in relation to virus load in long-term survivors of HIV-1 infection

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Human immunodeficiency virus type 1 nef quasispecies in pathological tissue

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

In vitro binding and phosphorylation of human immunodeficiency virus type 1 Nef protein by serine/threonine protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Urokinase plasminogen activator receptor, beta 2-integrins, and Src-kinases within a single receptor complex of human monocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

The Src family of tyrosine protein kinases in hemopoietic signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

CD4 cell surface downregulation in HIV-1 Nef transgenic mice is a consequence of intracellular sequestration.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

SH3-mediated Hck tyrosine kinase activation and fibroblast transformation by the Nef protein of HIV-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Patterns of HIV-1 mRNA expression in transgenic mice are tissue-dependent

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Nef association with human immunodeficiency virus type 1 virions and cleavage by the viral protease

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Insights on the pathogenicity of human T-lymphotropic/leukemia virus types I and II.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

The proteolytic cleavage of human immunodeficiency virus type 1 Nef does not correlate with its ability to stimulate virion infectivity.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Differential effects of nef on HIV replication: implications for viral pathogenesis in the host

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

The growth advantage conferred by HIV-1 nef is determined at the level of viral DNA formation and is independent of CD4 downregulation.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Optimal infectivity in vitro of human immunodeficiency virus type 1 requires an intact nef gene.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Molecular biology and pathogenesis of animal lentivirus infections.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

The role of HIV1 Nef in T-cell activation: Nef impairs induction of Th1 cytokines and interacts with the Src family tyrosine kinase Lck.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Physical and functional interaction of Nef with Lck. HIV-1 Nef-induced T-cell signaling defects.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Evidence for intact CD28 signaling in T cell hyporesponsiveness induced by the HIV-1nef gene

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Protective effects of a live attenuated SIV vaccine with a deletion in the nef gene

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Thioltransferase (glutaredoxin) is detected within HIV-1 and can regulate the activity of glutathionylated HIV-1 protease in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Natural HIV-1 NEF accelerates virus replication in primary human lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Identification of a nef allele that causes lymphocyte activation and acute disease in macaque monkeys

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

The human immunodeficiency virus type 1 Nef protein binds the Src-related tyrosine kinase Lck SH2 domain through a novel phosphotyrosine independent mechanism.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Activation of Vav by Nef induces cytoskeletal rearrangements and downstream effector functions

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Neurovirulent simian immunodeficiency virus incorporates a Nef-associated kinase activity into virions

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Inhibition of MHC class I antigen presentation by viral proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Analysis of alternatively spliced human immunodeficiency virus type-1 mRNA species, one of which encodes a novel tat-env fusion protein

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

HIV-1 directly kills CD4+ T cells by a Fas-independent mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Serine phosphorylation-independent downregulation of cell-surface CD4 by nef

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Dissociation of the CD4 downregulation and viral infectivity enhancement functions of human immunodeficiency virus type 1 Nef.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Co-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

The SH3 domain-binding surface and an acidic motif in HIV-1 Nef regulate trafficking of class I MHC complexes

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Declining CD4 T-cell counts in a person infected with nef-deleted HIV-1

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Human immunodeficiency virus type 1 Nef binds directly to Lck and mitogen-activated protein kinase, inhibiting kinase activity

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Nef 27, but not the Nef 25 isoform of human immunodeficiency virus-type 1 pNL4.3 down-regulates surface CD4 and IL-2R expression in peripheral blood mononuclear cells and transformed T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

The solution structure of HIV-1 Nef reveals an unexpected fold and permits delineation of the binding surface for the SH3 domain of Hck tyrosine protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

The CD4 determinant for downregulation by HIV-1 Nef directly binds to Nef. Mapping of the Nef binding surface by NMR.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

HIV F/3' orf encodes a phosphorylated GTP-binding protein resembling an oncogene product

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Identification of cellular proteins that bind to the human immunodeficiency virus type 1 nef gene product in vitro: a role for myristylation

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Myristoylation-dependent binding of HIV-1 Nef to CD4.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Apoptosis of CD8+ T cells is mediated by macrophages through interaction of HIV gp120 with chemokine receptor CXCR4.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Viral counts count in HIV infection

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Binding of c-Raf1 kinase to a conserved acidic sequence within the carboxyl-terminal region of the HIV-1 Nef protein

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Characterization of nef sequences in long-term survivors of human immunodeficiency virus type 1 infection

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

A tail of two src's: mutatis mutandis

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Separable functions of Nef disrupt two aspects of T cell receptor machinery: CD4 expression and CD3 signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Modulation of HIV-1 infectivity by MAPK, a virion-associated kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Requirement of human immunodeficiency virus type 1 nef for in vivo replication and pathogenicity

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Importance of the nef gene for maintenance of high virus loads and for development of AIDS

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Expression and cellular localization of the Nef protein from human immunodeficiency virus-1 in stably transfected B-cells

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Oligomerization of the Nef protein from human immunodeficiency virus (HIV) type 1.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Sequence variations in human immunodeficiency virus type 1 Nef are associated with different stages of disease

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Upstream U3 sequences in simian immunodeficiency virus are selectively deleted in vivo in the absence of an intact nef gene.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Cellular localization of Nef expressed in persistently HIV-1-infected low-producer astrocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Nef interacts with the mu subunit of clathrin adaptor complexes and reveals a cryptic sorting signal in MHC I molecules

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Analysis of Nef-induced MHC-I endocytosis

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Immunologic and virologic status after 14 to 18 years of infection with an attenuated strain of HIV-1. A report from the Sydney Blood Bank Cohort

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

A single amino acid in the SH3 domain of Hck determines its high affinity and specificity in binding to HIV-1 Nef protein

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

A novel di-leucine motif and a tyrosine-based motif independently mediate lysosomal targeting and endocytosis of CD3 chains

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Binding of HIV-1 Nef to a novel thioesterase enzyme correlates with Nef-mediated CD4 down-regulation

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Two elements target SIV Nef to the AP-2 clathrin adaptor complex, but only one is required for the induction of CD4 endocytosis

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

CDC42 and Rac1 are implicated in the activation of the Nef-associated kinase and replication of HIV-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Expression of HIV-1 nef in yeast: the 27 kDa Nef protein is myristylated and fractionates with the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Human immunodeficiency virus type 1 (HIV-1) provirus expression and LTR transcription are repressed in NEF-expressing cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

The multifaceted role of HIV Nef.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

The HIV-1 Nef protein acts as a connector with sorting pathways in the Golgi and at the plasma membrane

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Nef-induced CD4 and major histocompatibility complex class I (MHC-I) down-regulation are governed by distinct determinants: N-terminal alpha helix and proline repeat of Nef selectively regulate MHC-I trafficking

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

SH3-Domain binding function of HIV-1 Nef is required for association with a PAK-related kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Reduced rate of disease development after HIV-2 infection as compared to HIV-1

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Prognosis in HIV-1 infection predicted by the quantity of virus in plasma

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Defective accessory genes in a human immunodeficiency virus type 1-infected long-term survivor lacking recoverable virus

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Intravirion generation of the C-terminal core domain of HIV-1 Nef by the HIV-1 protease is insufficient to enhance viral infectivity

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

The human immunodeficiency virus-1 nef gene product: a positive factor for viral infection and replication in primary lymphocytes and macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Expression of the human immunodeficiency virus type 1 (HIV-1) nef gene during HIV-1 production increases progeny particle infectivity independently of gp160 or viral entry.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Activation of the Src-family tyrosine kinase Hck by SH3 domain displacement

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

The HIV-1 regulatory protein Nef has a specific function in viral expression in a murine macrophage cell line.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

The emergence of simian/human immunodeficiency viruses

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Functional analysis of HIV1 and SIV Nef proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

HIV-1 Nef protein inhibits the recruitment of AP-1 DNA-binding activity in human T-cells

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Myristoylation-enhanced binding of the HIV-1 Nef protein to T cell skeletal matrix.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Deletion of the nef gene abrogates the ability of SIV smmPBj to induce acutely lethal disease in pigtail macaques

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Virological importance of the protease-cleavage site in human immunodeficiency virus type 1 Nef is independent of both intravirion processing and CD4 down-regulation.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Producer-cell modification of human immunodeficiency virus type 1: Nef is a virion protein

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Evolutionary pattern of human immunodeficiency virus (HIV) replication and distribution in lymph nodes following primary infection: implications for antiviral therapy

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Mechanism of Nef-induced CD4 endocytosis: Nef connects CD4 with the mu chain of adaptor complexes

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

The nef gene from a long-term HIV type 1 nonprogressor

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Alternative splicing of human immunodeficiency virus type 1 mRNA modulates viral protein expression, replication, and infectivity.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Expression kinetics and subcellular localization of HIV-1 regulatory proteins Nef, Tat and Rev in acutely and chronically infected lymphoid cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Identification of a ten-amino acid proline-rich SH3 binding site

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Human immunodeficiency virus type 1 Nef-induced down-modulation of CD4 is due to rapid internalization and degradation of surface CD4.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

The role of clathrin, adaptors and dynamin in endocytosis

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

The HIV-1 nef protein inhibits extracellular signal-regulated kinase-dependent DNA synthesis in a human astrocytic cell line.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Inhibition of HIV-1 progeny virion release by cell-surface CD4 is relieved by expression of the viral Nef protein

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

HsN3 proteasomal subunit as a target for human immunodeficiency virus type 1 Nef protein.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Nef-CD4 physical interaction sensed with the yeast two-hybrid system

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

The Tyrosine-17 Residue of Nef in SIVsmmPBj14 Is Required for Acute Pathogenesis and Contributes to Replication in Macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

A conserved domain and membrane targeting of Nef from HIV and SIV are required for association with a cellular serine kinase activity

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Activation of PAK by HIV and SIV Nef: importance for AIDS in rhesus macaques

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Microtubule integrity regulates src-like and extracellular signal-regulated kinase activities in human pro-monocytic cells. Importance for interleukin-1 production

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Endocytosis of major histocompatibility complex class I molecules is induced by the HIV–1 Nef protein

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Reduced cell surface expression of processed human immunodeficiency virus type 1 envelope glycoprotein in the presence of Nef.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Loss of the SIVsmmPBj14 phenotype and nef genotype during long-term survival of macaques infected by mucosal routes

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Analysis of human immunodeficiency virus type 1 nef gene sequences present in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Crystal structure of the Src family tyrosine kinase Hck

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Altered T cell activation and development in transgenic mice expressing the HIV-1 nef gene

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Photolabeling of Prostaglandin Endoperoxide H Synthase-1 with 3-Trifluoro-3-(m-Iiodophenyl)diazirine as a Probe of Membrane Association and the Cyclooxygenase Active Site

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

The importance of nef in the induction of human immunodeficiency virus type 1 replication from primary quiescent CD4 lymphocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

The Nef protein of human immunodeficiency virus type 1 enhances serine phosphorylation of the viral matrix

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Evidence of Nef truncation in human immunodeficiency virus type 2 infection

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Complex Evolutionary History of Primate LentiviralvprGenes

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Constitutive expression of the nef gene suppresses human immunodeficiency virus type 1 (HIV-1) replication in monocytic cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

HIV-1 attachment: another look.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Alterations of the lymphocyte-specific protein tyrosine kinase (p56lck) during T-cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

A novel acyl-CoA thioesterase enhances its enzymatic activity by direct binding with HIV Nef

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

T cell antigen receptor signal transduction: a tale of tails and cytoplasmic protein-tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Signal transduction by lymphocyte antigen receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

The efficiency of acute infection of CD4+ T cells is markedly enhanced in the setting of antigen-specific immune activation

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Cytokine regulation of HIV replication induced by dendritic cell-CD4-positive T cell interactions

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Virion incorporation of human immunodeficiency virus type 1 Nef is mediated by a bipartite membrane-targeting signal: analysis of its role in enhancement of viral infectivity.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Human immunodeficiency virus type 1 Nef protein is incorporated into virus particles and specifically cleaved by the viral proteinase

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

HIV-1 Nef association with cellular serine kinase correlates with enhanced virion infectivity and efficient proviral DNA synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Vaccine protection by a triple deletion mutant of simian immunodeficiency virus.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Induction of Fas ligand expression by HIV involves the interaction of Nef with the T cell receptor zeta chain

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Evasion of cytotoxic T lymphocyte (CTL) responses by nef-dependent induction of Fas ligand (CD95L) expression on simian immunodeficiency virus-infected cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Degradation of CD4 induced by human immunodeficiency virus type 1 Vpu protein: a predicted alpha-helix structure in the proximal cytoplasmic region of CD4 contributes to Vpu sensitivity

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

Effect of myristoylation on p27nef subcellular distribution and suppression of HIV-LTR transcription

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948010-5

7 January 2021

10.1016/S1054-3589(00)48010-5

Identifiers

DOI

1 reference

30 July 2017

1 reference

PubMed ID

10987095