(Q34050163)

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MHC-I-restricted melanoma antigen specific TCR-engineered human CD4+ T cells exhibit multifunctional effector and helper responses, in vitro

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5 February 2020

MHC-I-restricted melanoma antigen specific TCR-engineered human CD4+ T cells exhibit multifunctional effector and helper responses, in vitro (English)

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5 February 2020

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5 February 2020

Steven Rosenberg

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Steven A Rosenberg

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5 February 2020

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Swagatam Ray

1

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5 February 2020

Nitya G Chakraborty

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5 February 2020

Upendra Hegde

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5 February 2020

David I Dorsky

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5 February 2020

Thinle Chodon

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5 February 2020

Erika von Euw

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5 February 2020

Begonya Comin-Anduix

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5 February 2020

Richard C Koya

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5 February 2020

Antoni Ribas

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5 February 2020

James S Economou

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5 February 2020

Bijay Mukherji

13

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5 February 2020

UCLA-CALTECH-CHLA-USC-UCONN Consortium on Translational Program in Engineered Immunity

14

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5 February 2020

publication date

23 May 2010

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5 February 2020

Clinical Immunology

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5 February 2020

136

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5 February 2020

3

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5 February 2020

338-347

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5 February 2020

Tumor-reactive CD4(+) T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917536

28 July 2018

Obstacles to and opportunities for more effective peptide-based therapeutic immunization in human melanoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917536

28 July 2018

Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917536

28 July 2018

CTLA-4 blockade enhances polyfunctional NY-ESO-1 specific T cell responses in metastatic melanoma patients with clinical benefit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917536

28 July 2018

Adoptive cell therapy for patients with metastatic melanoma: evaluation of intensive myeloablative chemoradiation preparative regimens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917536

28 July 2018

CD4+CD25- T cells transduced to express MHC class I-restricted epitope-specific TCR synthesize Th1 cytokines and exhibit MHC class I-restricted cytolytic effector function in a human melanoma model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917536

28 July 2018

T-cell quality in memory and protection: implications for vaccine design

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917536

28 July 2018

Polyfunctional T cell responses are a hallmark of HIV-2 infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917536

28 July 2018

Gene transfer of tumor-reactive TCR confers both high avidity and tumor reactivity to nonreactive peripheral blood mononuclear cells and tumor-infiltrating lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917536

28 July 2018

Cancer regression in patients after transfer of genetically engineered lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917536

28 July 2018

CD8 alpha coreceptor to improve TCR gene transfer to treat melanoma: down-regulation of tumor-specific production of IL-4, IL-5, and IL-10.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917536

28 July 2018

Generation of T cell help through a MHC class I-restricted TCR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917536

28 July 2018

CD4+ T lymphocytes: a critical component of antitumor immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917536

28 July 2018

A critical role of T cell antigen receptor-transduced MHC class I-restricted helper T cells in tumor protection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917536

28 July 2018

Simultaneous generation of CD8+ and CD4+ melanoma-reactive T cells by retroviral-mediated transfer of a single T-cell receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917536

28 July 2018

Redirecting human CD4+ T lymphocytes to the MHC class I-restricted melanoma antigen MAGE-A1 by TCR alphabeta gene transfer requires CD8alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917536

28 July 2018

Helping the CD8(+) T-cell response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917536

28 July 2018

T-cell-based immunotherapy of melanoma: what have we learned and how can we improve?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917536

28 July 2018

High efficiency TCR gene transfer into primary human lymphocytes affords avid recognition of melanoma tumor antigen glycoprotein 100 and does not alter the recognition of autologous melanoma antigens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917536

28 July 2018

Analysing cell division in vivo and in vitro using flow cytometric measurement of CFSE dye dilution.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917536

28 July 2018

CD4 T cells and their role in antitumor immune responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917536

28 July 2018

Helper activity is required for the in vivo generation of cytotoxic T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917536

28 July 2018

Naive tumor-specific CD4(+) T cells differentiated in vivo eradicate established melanoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917536

28 October 2018

Generation of tumor-specific, HLA class I-restricted human Th1 and Tc1 cells by cell engineering with tumor peptide-specific T-cell receptor genes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917536

28 October 2018

CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917536

28 October 2018

Influence of Human CD8 on Antigen Recognition by T-Cell Receptor-Transduced Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917536

28 October 2018

Regulation of melanoma epitope-specific cytolytic T lymphocyte response by immature and activated dendritic cells, in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/20547105

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cross-presentation of a human tumor antigen delivered to dendritic cells by HSV VP22-mediated protein translocation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20547105

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor regression responses in melanoma patients treated with a peptide encoded by gene MAGE-3

1 reference

https://pubmed.ncbi.nlm.nih.gov/20547105

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vaccination of melanoma patients with peptide- or tumor lysate-pulsed dendritic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20547105

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of CD4+ T cell responses in antitumor immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20547105

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficient transfer of a tumor antigen-reactive TCR to human peripheral blood lymphocytes confers anti-tumor reactivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20547105

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MHC class I TCR engineered anti-tumor CD4 T cells: implications for cancer immunotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20547105

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.CLIM.2010.04.013

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Europe PubMed Central

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5 February 2020

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5 February 2020

PubMed publication ID

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5 February 2020

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