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Genetic connections between neurological disorders and cholesterol metabolism
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Europe PubMed Central
PMC publication ID
2918434
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2 February 2020
title
Genetic connections between neurological disorders and cholesterol metabolism
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
2918434
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20466796%20AND%20SRC:MED&resulttype=core&format=json
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2 February 2020
author
Ingemar Björkhem
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1
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Europe PubMed Central
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2918434
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20466796%20AND%20SRC:MED&resulttype=core&format=json
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2 February 2020
Ingemar Björkhem
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2
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Europe PubMed Central
PMC publication ID
2918434
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20466796%20AND%20SRC:MED&resulttype=core&format=json
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2 February 2020
Steve Meaney
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4
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2918434
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2 February 2020
author name string
Valerio Leoni
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3
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2 February 2020
publication date
13 May 2010
1 reference
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Europe PubMed Central
PMC publication ID
2918434
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2 February 2020
published in
Journal of Lipid Research
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stated in
Europe PubMed Central
PMC publication ID
2918434
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20466796%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
volume
51
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Europe PubMed Central
PMC publication ID
2918434
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20466796%20AND%20SRC:MED&resulttype=core&format=json
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2 February 2020
issue
9
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Europe PubMed Central
PMC publication ID
2918434
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20466796%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
page(s)
2489-2503
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Europe PubMed Central
PMC publication ID
2918434
reference URL
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retrieved
2 February 2020
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28 July 2018
Apolipoprotein E fragments present in Alzheimer's disease brains induce neurofibrillary tangle-like intracellular inclusions in neurons
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28 July 2018
Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model
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28 July 2018
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28 July 2018
Expression of human apolipoprotein E4 in neurons causes hyperphosphorylation of protein tau in the brains of transgenic mice
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28 July 2018
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Expression of human apolipoprotein E3 or E4 in the brains of Apoe-/- mice: isoform-specific effects on neurodegeneration.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 July 2018
Expression of human apolipoprotein E reduces amyloid-beta deposition in a mouse model of Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 July 2018
Identification of a new inborn error in bile acid synthesis: mutation of the oxysterol 7alpha-hydroxylase gene causes severe neonatal liver disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 July 2018
Markedly reduced bile acid synthesis but maintained levels of cholesterol and vitamin D metabolites in mice with disrupted sterol 27-hydroxylase gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 July 2018
Huntington disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 July 2018
Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 July 2018
Identification and characterization of a mouse oxysterol 7alpha-hydroxylase cDNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 July 2018
Cyp7b, a novel brain cytochrome P450, catalyzes the synthesis of neurosteroids 7alpha-hydroxy dehydroepiandrosterone and 7alpha-hydroxy pregnenolone
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 July 2018
Hypothesis: microtubule instability and paired helical filament formation in the Alzheimer disease brain are related to apolipoprotein E genotype
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 July 2018
Induction of Alzheimer-like beta-amyloid immunoreactivity in the brains of rabbits with dietary cholesterol
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 July 2018
Long-term treatment of cerebrotendinous xanthomatosis with chenodeoxycholic acid
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 July 2018
Comparative effects of cholestanol and cholesterol on hepatic sterol and bile acid metabolism in the rat.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 July 2018
A defect in cholesterol esterification in Niemann-Pick disease (type C) patients
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 July 2018
Accumulation of 7 alpha-hydroxy-4-cholesten-3-one and cholesta-4,6-dien-3-one in patients with cerebrotendinous xanthomatosis: effect of treatment with chenodeoxycholic acid
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 July 2018
Neuropathological classification of Huntington's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 July 2018
Marked accumulation of 27-hydroxycholesterol in SPG5 patients with hereditary spastic paresis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
Adeno-associated virus gene therapy with cholesterol 24-hydroxylase reduces the amyloid pathology before or after the onset of amyloid plaques in mouse models of Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
Absence of ApoE upregulates murine brain ApoD and ABCA1 levels, but does not affect brain sterol levels, while human ApoE3 and human ApoE4 upregulate brain cholesterol precursor levels.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
Cholesterol regulates the endoplasmic reticulum exit of the major membrane protein P0 required for peripheral myelin compaction.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
CYP7B1 mutations in pure and complex forms of hereditary spastic paraplegia type 5.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
Two novel CYP7B1 mutations in Italian families with SPG5: a clinical and genetic study.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
White matter lesions in spastic paraplegia with mutations in SPG5/CYP7B1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
The early and ongoing experience with the cholesterol-fed rabbit as a model of Alzheimer's disease: the old, the new and the pilot.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
apoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
Analysis of CYP7B1 in non-consanguineous cases of hereditary spastic paraplegia.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
NPC2 facilitates bidirectional transfer of cholesterol between NPC1 and lipid bilayers, a step in cholesterol egress from lysosomes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
Plasma 24S-hydroxycholesterol and caudate MRI in pre-manifest and early Huntington's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
Activity-regulated cytoskeleton-associated protein in rodent brain is down-regulated by high fat diet in vivo and by 27-hydroxycholesterol in vitro
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
Neonatal cholestatic liver disease in an Asian patient with a homozygous mutation in the oxysterol 7alpha-hydroxylase gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
Apolipoprotein E and Alzheimer's disease: molecular mechanisms and therapeutic opportunities.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
Purified NPC1 protein. I. Binding of cholesterol and oxysterols to a 1278-amino acid membrane protein.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
Progressive dysfunction of the cholesterol biosynthesis pathway in the R6/2 mouse model of Huntington's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
Unique patient with cerebrotendinous xanthomatosis. Evidence for presence of a defect in a gene that is not identical to sterol 27-hydroxylase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
On the mechanism of cerebral accumulation of cholestanol in patients with cerebrotendinous xanthomatosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
Novel route for elimination of brain oxysterols across the blood-brain barrier: conversion into 7alpha-hydroxy-3-oxo-4-cholestenoic acid.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
Cleavage at the caspase-6 site is required for neuronal dysfunction and degeneration due to mutant huntingtin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
24(S)-hydroxycholesterol participates in a liver X receptor-controlled pathway in astrocytes that regulates apolipoprotein E-mediated cholesterol efflux.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
Implication of apoE isoforms in cholesterol metabolism by primary rat hippocampal neurons and astrocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
Dysfunction of the cholesterol biosynthetic pathway in Huntington's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
Patients with atherosclerosis may have increased circulating levels of 27-hydroxycholesterol and cholestenoic acid
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
Mutation in the sterol 27-hydroxylase gene associated with fatal cholestasis in infancy.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
High cholesterol level is essential for myelin membrane growth
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
Crossing the barrier: net flux of 27-hydroxycholesterol into the human brain.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
Generation of viable cholesterol-free mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
Changes in the levels of cerebral and extracerebral sterols in the brain of patients with Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
Feedback regulation of bile acid synthesis in primary human hepatocytes: evidence that CDCA is the strongest inhibitor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
Spatial and temporal distribution of intracellular free cholesterol in brains of a Niemann-Pick type C mouse model showing hyperphosphorylated tau protein. Implications for Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
Mutations in the sterol 27-hydroxylase gene (CYP27A) cause hepatitis of infancy as well as cerebrotendinous xanthomatosis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
The enzymes, regulation, and genetics of bile acid synthesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
Cholesterol accumulates in cell bodies, but is decreased in distal axons, of Niemann-Pick C1-deficient neurons
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
The sterol-sensing domain: multiple families, a unique role?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
Regional and progressive thinning of the cortical ribbon in Huntington's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
Oxysterols induce interleukin-1beta production in human macrophages
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
Cholesterol and neuropathologic markers of AD: a population-based autopsy study
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
Identification of unusual 7-oxygenated bile acid sulfates in a patient with Niemann-Pick disease, type C.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
From brain to bile. Evidence that conjugation and omega-hydroxylation are important for elimination of 24S-hydroxycholesterol (cerebrosterol) in humans
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
Midlife vascular risk factors and late-life mild cognitive impairment: A population-based study
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
Disturbance of neuronal plasticity is a critical pathogenetic event in Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
24-hydroxycholesterol is a substrate for hepatic cholesterol 7alpha-hydroxylase (CYP7A).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
Regional difference of lipid distribution in brain of apolipoprotein E deficient mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
Axonal transport of N-terminal huntingtin suggests early pathology of corticostriatal projections in Huntington disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
Primary structure of EPV20, a secretory glycoprotein containing a previously uncharacterized type of domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
Ouchterlony double immunodiffusion method demonstrates absence of ferritin immunoreactivity in visceral organs from nine patients with Niemann-Pick disease type C.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
Toxicity of oxysterols to human monocyte-macrophages.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
Frequency and distribution of Alzheimer's disease in Europe: a collaborative study of 1980-1990 prevalence findings. The EURODEM-Prevalence Research Group.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
HE1/NPC2 status in human reproductive tract and ejaculated spermatozoa: consequence of vasectomy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
28 October 2018
Elimination of cholesterol in macrophages and endothelial cells by the sterol 27-hydroxylase mechanism. Comparison with high density lipoprotein-mediated reverse cholesterol transport
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2918434
retrieved
10 December 2018
Gene set enrichment analyses revealed several affected pathways in Niemann-pick disease type C fibroblasts
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20466796
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
On the structural specificity in the regulation of the hydroxymethylglutaryl-CoA reductase and the cholesterol-7 alpha-hydroxylase in rats. Effects of cholestanol feeding
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20466796
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Effects of 3 beta-[2-(diethylamino)ethoxy]androst-5-en-17-one on the synthesis of cholesterol and ubiquinone in rat intestinal epithelial cell cultures
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20466796
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Macrophages isolated from human atherosclerotic plaques produce IL-8, and oxysterols may have a regulatory function for IL-8 production
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20466796
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Down-regulation of hepatic HMG-CoA reductase in mice by dietary cholesterol: importance of the delta 5 double bond and evidence that oxidation at C-3, C-5, C-6, or C-7 is not involved
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20466796
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Astrocytes synthesize apolipoprotein E and metabolize apolipoprotein E-containing lipoproteins
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20466796
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Deficient Ferritin Immunoreactivity in Visceral Organs from Four Patients with Niemann-Pick Disease Type C
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20466796
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1194/JLR.R006338
1 reference
stated in
Europe PubMed Central
PMC publication ID
2918434
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20466796%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
PMC publication ID
2918434
1 reference
stated in
Europe PubMed Central
PMC publication ID
2918434
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20466796%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
PubMed publication ID
20466796
1 reference
stated in
Europe PubMed Central
PMC publication ID
2918434
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20466796%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
ResearchGate publication ID
44596248
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