(Q35790921)

10 August 2017

1 reference

title

Protein misfolding in neurodegenerative diseases (English)

1 reference

10 August 2017

1 reference

Georgios M Hadjigeorgiou

series ordinal

4

object named as

Hadjigeorgiou GM

1 reference

10 August 2017

Agorogiannis EI

1

1 reference

PubMed ID

15175075

10 August 2017

Agorogiannis GI

series ordinal

2

1 reference

PubMed ID

15175075

10 August 2017

Papadimitriou A

series ordinal

3

1 reference

10 August 2017

1 June 2004

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Neuropathology and Applied Neurobiology

10 August 2017

1 reference

10 August 2017

30

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10 August 2017

215-224

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10 August 2017

3

1 reference

Amyloid diseases: abnormal protein aggregation in neurodegeneration

10 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Evolution of amyloid: what normal protein folding may tell us about fibrillogenesis and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Molecular chaperones in the cytosol: from nascent chain to folded protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Themes and variations on ubiquitylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Impairment of the ubiquitin-proteasome system by protein aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Amyloid beta-protein fibrillogenesis. Detection of a protofibrillar intermediate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Neurodegenerative disease: amyloid pores from pathogenic mutations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: a case report.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Toxic proteins in neurodegenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Genetic classification of primary neurodegenerative disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

The ubiquitin pathway in Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Mutations in NR4A2 associated with familial Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Recent advances in the genetics and pathogenesis of Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

The formation of highly soluble oligomers of alpha-synuclein is regulated by fatty acids and enhanced in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Dopamine-dependent neurotoxicity of alpha-synuclein: a mechanism for selective neurodegeneration in Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Interaction of Akt-phosphorylated ataxin-1 with 14-3-3 mediates neurodegeneration in spinocerebellar ataxia type 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Spongiform degeneration in mahoganoid mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Lewy bodies and parkinsonism in families with parkin mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Molecular basis of the neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Huntingtin inclusions do not deplete polyglutamine-containing transcription factors in HD mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Protein misfolding, amyloid formation, and neurodegeneration: a critical role for molecular chaperones?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Mechanisms of chaperone suppression of polyglutamine disease: selectivity, synergy and modulation of protein solubility in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Pivotal role of oligomerization in expanded polyglutamine neurodegenerative disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Mutation of the E6-AP ubiquitin ligase reduces nuclear inclusion frequency while accelerating polyglutamine-induced pathology in SCA1 mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Disruption of Axonal Transport by Loss of Huntingtin or Expression of Pathogenic PolyQ Proteins in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Evidence for early cytotoxic aggregates in transgenic mice for human transthyretin Leu55Pro

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Shattuck lecture--neurodegenerative diseases and prions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Yeast genes that enhance the toxicity of a mutant huntingtin fragment or alpha-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Apoptosis in the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Disruption of axonal transport and neuronal viability by amyloid precursor protein mutations in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Kinesin-mediated axonal transport of a membrane compartment containing beta-secretase and presenilin-1 requires APP

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Do disorders of movement cause movement disorders and dementia?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Genetic suppression of polyglutamine toxicity in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

The 1.6-A crystal structure of the class of chaperones represented by Escherichia coli Hsp31 reveals a putative catalytic triad

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Inflammation and therapeutic vaccination in CNS diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

Prevention of transthyretin amyloid disease by changing protein misfolding energetics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2990.2004.00558.X

10.1111/J.1365-2990.2004.00558.X

21 January 2018

Identifiers

DOI

1 reference

10 August 2017

1 reference

PubMed ID

15175075