(Q34055302)

30 July 2017

title

The anti-sigma factor TcdC modulates hypervirulence in an epidemic BI/NAP1/027 clinical isolate of Clostridium difficile (English)

1 reference

30 July 2017

main subject

Clostridium difficile

0 references

1 reference

Glen P Carter

1

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Anthony M Buckley

object named as

Anthony M Buckley

7

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Dena Lyras

object named as

Dena Lyras

13

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Julian I. Rood

object named as

Julian I Rood

12

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author name string

Gillian R Douce

2

1 reference

30 July 2017

Revathi Govind

3

1 reference

30 July 2017

Pauline M Howarth

4

1 reference

30 July 2017

Kate E Mackin

5

1 reference

30 July 2017

Janice Spencer

6

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30 July 2017

Ana Antunes

8

1 reference

30 July 2017

Despina Kotsanas

9

1 reference

30 July 2017

Grant A Jenkin

10

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30 July 2017

Bruno Dupuy

11

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30 July 2017

publication date

13 October 2011

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30 July 2017

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30 July 2017

volume

7

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30 July 2017

issue

10

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30 July 2017

page(s)

e1002317

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Creative Commons Attribution 4.0 International

30 July 2017

copyright license

start time

13 October 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3192846/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Variations in TcdB activity and the hypervirulence of emerging strains of Clostridium difficile

5 July 2018

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Human Hypervirulent Clostridium difficile Strains Exhibit Increased Sporulation as Well as Robust Toxin Production

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium

5 July 2018

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5 July 2018

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Antibiotic treatment of clostridium difficile carrier mice triggers a supershedder state, spore-mediated transmission, and severe disease in immunocompromised hosts

5 July 2018

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Truncation in the tcdC region of the Clostridium difficile PathLoc of clinical isolates does not predict increased biological activity of Toxin B or Toxin A

5 July 2018

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5 July 2018

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Toxin B is essential for virulence of Clostridium difficile

5 July 2018

1 reference

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Comparative analysis of BI/NAP1/027 hypervirulent strains reveals novel toxin B-encoding gene (tcdB) sequences

5 July 2018

1 reference

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Clostridium difficile toxin synthesis is negatively regulated by TcdC.

5 July 2018

1 reference

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5 July 2018

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Binary toxin production in Clostridium difficile is regulated by CdtR, a LytTR family response regulator

5 July 2018

1 reference

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tcdC genotypes associated with severe TcdC truncation in an epidemic clone and other strains of Clostridium difficile

5 July 2018

1 reference

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Emergence of Clostridium difficile-associated disease in North America and Europe.

5 July 2018

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Construction and analysis of chromosomal Clostridium difficile mutants

5 July 2018

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5 July 2018

1 reference

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The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Evidence for holin function of tcdE gene in the pathogenicity of Clostridium difficile

5 July 2018

1 reference

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5 July 2018

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5 July 2018

1 reference

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Transcription analysis of the genes tcdA-E of the pathogenicity locus of Clostridium difficile

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192846

Definition of the single integration site of the pathogenicity locus in Clostridium difficile.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192846

Glucosylation of Rho proteins by Clostridium difficile toxin B.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192846

Virulence studies on chromosomal alpha-toxin and theta-toxin mutants constructed by allelic exchange provide genetic evidence for the essential role of alpha-toxin in Clostridium perfringens-mediated gas gangrene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192846

Transferable tetracycline resistance in Clostridium difficile

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192846

Investigation of an outbreak of antibiotic-associated colitis by various typing methods

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192846

A complementation analysis of the restriction and modification of DNA in Escherichia coli

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192846

Genetic analysis of a tetracycline resistance element from Clostridium difficile and its conjugal transfer to and from Bacillus subtilis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192846

Transfer of Tn916 and Tn916ΔE into Clostridium difficile: demonstration of a hot-spot for these elements in the C. difficile genome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192846

Characterization of a toxin A-negative, toxin B-positive strain of Clostridium difficile

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192846

Pathogenesis of Clostridium difficile infection

5 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002317

A large outbreak of Clostridium difficile-associated disease with an unexpected proportion of deaths and colectomies at a teaching hospital following increased fluoroquinolone use.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002317

SleC is essential for germination of Clostridium difficile spores in nutrient-rich medium supplemented with the bile salt taurocholate

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002317

The ClosTron: Mutagenesis in Clostridium refined and streamlined.

21 January 2018

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Construction of improved temperature-sensitive and mobilizable vectors and their use for constructing mutations in the adhesin-encoding acm gene of poorly transformable clinical Enterococcus faecium strains

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002317

Isolation of alpha-toxin, theta-toxin and kappa-toxin mutants of Clostridium perfringens by Tn916 mutagenesis

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002317

Infection of hamsters with historical and epidemic BI types of Clostridium difficile

21 January 2018

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The development of Clostridium difficile genetic systems.

21 January 2018

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Clostridium difficile PCR ribotype 078: an emerging strain in humans and in pigs?

21 January 2018

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Toxin production by an emerging strain of Clostridium difficile associated with outbreaks of severe disease in North America and Europe

21 January 2018

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Clostridium difficile toxin expression is inhibited by the novel regulator TcdC

21 January 2018

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12 December 2020

The ClosTron: a universal gene knock-out system for the genus Clostridium

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12 December 2020

Severe infection with Clostridium difficile PCR ribotype 027 acquired in Melbourne, Australia

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12 December 2020

Is Clostridium difficile a threat to Australia's biosecurity?

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12 December 2020

Clostridium difficile–associated diarrhea: an emerging threat to pregnant women

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12 December 2020

10.1371/JOURNAL.PPAT.1002317

Identifiers

DOI

1 reference

30 July 2017

1 reference

30 July 2017

1 reference