(Q34057800)

30 July 2017

The role of co-inhibitory signals driven by CTLA-4 in immune system (English)

1 reference

30 July 2017

Ivan Hirsch

4

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author name string

Daniel Olive

1

1 reference

30 July 2017

Suong le Thi

2

1 reference

30 July 2017

Luc Xerri

3

1 reference

30 July 2017

Jacques A Nunès

5

1 reference

30 July 2017

language of work or name

French

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publication date

21 October 2011

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30 July 2017

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30 July 2017

27

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30 July 2017

10

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30 July 2017

842-849

1 reference

Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy

30 July 2017

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20112710012

The role of the CD28 receptor during T cell responses to antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20112710012

CD28 activation pathway regulates the production of multiple T-cell-derived lymphokines/cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20112710012

Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20112710012

CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20112710012

Regulation of Interleukin-2 Gene Enhancer Activity by the T Cell Accessory Molecule CD28

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20112710012

Binding of phosphatidylinositol-3-OH kinase to CD28 is required for T-cell signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20112710012

CD28 and CTLA-4 coreceptor expression and signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20112710012

CD28 plays a critical role in the segregation of PKC theta within the immunologic synapse

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20112710012

Dynamic regulation of T cell activation and co-stimulation through TCR-microclusters

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20112710012

Complementarity determining region 1 (CDR1)- and CDR3-analogous regions in CTLA-4 and CD28 determine the binding to B7-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20112710012

Differential recognition by CD28 of its cognate counter receptors CD80 (B7.1) and B70 (B7.2): analysis by site directed mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20112710012

CD80 (B7-1) binds both CD28 and CTLA-4 with a low affinity and very fast kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20112710012

CTLA-4 is expressed by human monocyte-derived dendritic cells and regulates their functions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20112710012

Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20112710012

Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20112710012

CTLA-4 can function as a negative regulator of T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20112710012

Single dose of anti-CTLA-4 enhances CD8+ T-cell memory formation, function, and maintenance

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20112710012

Dual function of CTLA-4 in regulatory T cells and conventional T cells to prevent multiorgan autoimmunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20112710012

CTLA-4 suppresses the pathogenicity of self antigen-specific T cells by cell-intrinsic and cell-extrinsic mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20112710012

Insights into function of the immunological synapse from studies with supported planar bilayers

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20112710012

Spatiotemporal regulation of T cell costimulation by TCR-CD28 microclusters and protein kinase C theta translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20112710012

PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20112710012

Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accomp

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20112710012

Mechanisms of costimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20112710012

BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20112710012

B and T lymphocyte attenuator is highly expressed on CMV-specific T cells during infection and regulates their function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20112710012

Review: anti-CTLA-4 antibody ipilimumab: case studies of clinical response and immune-related adverse events

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20112710012

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20112710012

Spatiotemporal basis of CTLA-4 costimulatory molecule-mediated negative regulation of T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20112710012

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20112710012

10.1051/MEDSCI/20112710012

21 January 2018

Identifiers

DOI

1 reference

30 July 2017

0 references

1 reference