(Q34059491)

30 July 2017

title

Protein and RNA engineering to customize microbial molecular reporting (English)

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30 July 2017

2

Christopher S Frei

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30 July 2017

Joseph A Gredell

1

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30 July 2017

Patrick C Cirino

series ordinal

3

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30 July 2017

publication date

26 October 2011

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30 July 2017

published in

Biotechnology Journal

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30 July 2017

volume

7

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30 July 2017

issue

4

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30 July 2017

page(s)

477-499

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Engineering the maltose binding protein for reagentless fluorescence sensing

30 July 2017

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Directed evolution of Vibrio fischeri LuxR for increased sensitivity to a broad spectrum of acyl-homoserine lactones

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Directed evolution of Vibrio fischeri LuxR for improved response to butanoyl-homoserine lactone

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Dual selection enhances the signaling specificity of a variant of the quorum-sensing transcriptional activator LuxR.

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Structure of the Tet repressor-tetracycline complex and regulation of antibiotic resistance

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The complex formed between Tet repressor and tetracycline-Mg2+ reveals mechanism of antibiotic resistance

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Conformational changes of the Tet repressor induced by tetracycline trapping

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Structural basis of gene regulation by the tetracycline inducible Tet repressor-operator system

21 January 2018

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Structure-based design of Tet repressor to optimize a new inducer specificity

21 January 2018

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Activity reversal of Tet repressor caused by single amino acid exchanges

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100266

Two mutations in the tetracycline repressor change the inducer anhydrotetracycline to a corepressor

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100266

Independent regulation of two genes in Escherichia coli by tetracyclines and Tet repressor variants

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100266

Engineered Tet repressors with recognition specificity for the tetO-4C5G operator variant

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100266

AraC protein, regulation of the l-arabinose operon in Escherichia coli, and the light switch mechanism of AraC action

21 January 2018

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AraC regulatory protein mutants with altered effector specificity

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100266

Mutational analysis of residue roles in AraC function

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100266

Structural basis for ligand-regulated oligomerization of AraC

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100266

Biosynthesis of plant isoprenoids: perspectives for microbial engineering.

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100266

Engineering a mevalonate pathway in Escherichia coli for production of terpenoids

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100266

Design and application of a mevalonate-responsive regulatory protein.

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100266

Combinatorial engineering of intergenic regions in operons tunes expression of multiple genes

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100266

Deoxygenation of polyhydroxybenzenes: an alternative strategy for the benzene-free synthesis of aromatic chemicals

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100266

Engineered systems for detection and discovery of nuclear hormone-like compounds

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100266

Engineering orthogonal ligand-receptor pairs from "near drugs".

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100266

Chemical complementation: small-molecule-based genetic selection in yeast

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100266

Creation and discovery of ligand-receptor pairs for transcriptional control with small molecules

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100266

Directed evolution of human estrogen receptor variants with significantly enhanced androgen specificity and affinity

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100266

Yeast two-hybrid: so many interactions, (in) so little time...

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100266

Nuclear hormone receptors: ligand-activated regulators of transcription and diverse cell responses

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100266

Directed evolution of specific receptor-ligand pairs for use in the creation of gene switches

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100266

Crystallographic comparison of the estrogen and progesterone receptor's ligand binding domains

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100266

Rapid creation of a novel protein function by in vitro coevolution

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100266

The rational design of allosteric interactions in a monomeric protein and its applications to the construction of biosensors

21 January 2018

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Computational design of receptor and sensor proteins with novel functions

21 January 2018

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Genetic definition of a protein-splicing domain: functional mini-inteins support structure predictions and a model for intein evolution

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100266

Directed evolution of ligand dependence: small-molecule-activated protein splicing

21 January 2018

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A bacterial biosensor of endocrine modulators

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100266

Rapid detection of subtype-selective nuclear hormone receptor binding with bacterial genetic selection

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100266

Engineered chimeric enzymes as tools for drug discovery: generating reliable bacterial screens for the detection, discovery, and assessment of estrogen receptor modulators.

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100266

Construction of a bacterial assay for estrogen detection based on an estrogen-sensitive intein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Creation of an allosteric enzyme by domain insertion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Random circular permutation of genes and expressed polypeptide chains: application of the method to the catalytic chains of aspartate transcarbamoylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

A molecular switch created by in vitro recombination of nonhomologous genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Directed evolution of protein switches and their application to the creation of ligand-binding proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Extensive features of tight oligosaccharide binding revealed in high-resolution structures of the maltodextrin transport/chemosensory receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

In vitro selection of RNA molecules that bind specific ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Ribozymes and riboswitches: modulation of RNA function by small molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Functional nucleic acid sensors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Controlling gene expression in living cells through small molecule-RNA interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Genetic control by a metabolite binding mRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Thiamine derivatives bind messenger RNAs directly to regulate bacterial gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Sensing Small Molecules by Nascent RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Functional aptamers and aptazymes in biotechnology, diagnostics, and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Conditional gene expression by controlling translation with tetracycline-binding aptamers

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Tetracycline-aptamer-mediated translational regulation in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Molecular analysis of a synthetic tetracycline-binding riboswitch

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Thermodynamic characterization of an engineered tetracycline-binding riboswitch

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Tetracycline aptamer-controlled regulation of pre-mRNA splicing in yeast

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100266

A theophylline responsive riboswitch based on helix slipping controls gene expression in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Engineering precision RNA molecular switches

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100266

Screening for engineered neomycin riboswitches that control translation initiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

High-resolution molecular discrimination by RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Genetic screens and selections for small molecules based on a synthetic riboswitch that activates protein translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

A high-throughput screen for synthetic riboswitches reveals mechanistic insights into their function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Guiding bacteria with small molecules and RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Random walks to synthetic riboswitches--a high-throughput selection based on cell motility.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

A flow cytometry-based screen for synthetic riboswitches

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Reprogramming bacteria to seek and destroy an herbicide

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

A FACS-based approach to engineering artificial riboswitches

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Reengineering a natural riboswitch by dual genetic selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Structure and function of the class C tetracycline/H+ antiporter: three independent groups of phenotypes are conferred by TetA (C).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Engineering complex riboswitch regulation by dual genetic selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Ligand binding and gene control characteristics of tandem riboswitches in Bacillus anthracis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

A synthetic riboswitch with chemical band-pass response

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Programmable ligand-controlled riboregulators of eukaryotic gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Catalytic strategies of self-cleaving ribozymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Comparative enzymology and structural biology of RNA self-cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

A modular and extensible RNA-based gene-regulatory platform for engineering cellular function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Higher-order cellular information processing with synthetic RNA devices

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100266

An artificial aptazyme-based riboswitch and its cascading system in E. coli.

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100266

Artificial ribozyme switches containing natural riboswitch aptamer domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Small-molecule-dependent regulation of transfer RNA in bacteria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Aptazyme-mediated regulation of 16S ribosomal RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Analyzing mRNA-protein complexes using a yeast three-hybrid system

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

In vivo evolution of an RNA-based transcriptional activator

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Engineering a ligand-dependent RNA transcriptional activator

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Glucose biosensors: an overview of use in clinical practice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Status of biomolecular recognition using electrochemical techniques

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Transactivator mutants with altered effector specificity allow selective regulation of two genes by tetracycline variants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Genetic control of mammalian T-cell proliferation with synthetic RNA regulatory systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Reprogramming cellular behavior with RNA controllers responsive to endogenous proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

A ligand-dependent hammerhead ribozyme switch for controlling mammalian gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Artificial control of gene expression in mammalian cells by modulating RNA interference through aptamer-small molecule interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Exogenous control of mammalian gene expression through modulation of RNA self-cleavage

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100266

Characterization of a molecular switch system that regulates gene expression in mammalian cells through a small molecule

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100266

Miniaturising the laboratory in emulsion droplets

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Development of an in vitro compartmentalization screen for high-throughput directed evolution of [FeFe] hydrogenases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Directed evolution by in vitro compartmentalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Allosteric nucleic acid catalysts

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Effector Specificity Mutants of the Transcriptional Activator NahR of Naphthalene DegradingPseudomonasDefine Protein Sites Involved in Binding of Aromatic Inducers

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Cooperative amino acid changes shift the response of the σ54-dependent regulator XylR from natural m-xylene towards xenobiotic 2,4-dinitrotoluene

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

In situ detection of aromatic compounds with biosensor Pseudomonas putida cells preserved and delivered to soil in water-soluble gelatin capsules

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

Efficient Design Strategy for Whole-Cell and Cell-Free Biosensors based on Engineered Riboswitches

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

New pathway to polyketides in plants

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100266

21 January 2018

Identifiers

DOI

10.1002/BIOT.201100266

1 reference

30 July 2017

1 reference