(Q34064211)

30 July 2017

title

The SARS-coronavirus-host interactome: identification of cyclophilins as target for pan-coronavirus inhibitors (English)

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host translation inhibitor nsp1 [SARS-Cov]

30 July 2017

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25

Stefan Pöhlmann

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Susanne Pfefferle

1

Susanne Pfefferle

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Roland Züst

14

Roland Züst

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Caroline C Friedel

Caroline C Friedel

4

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Volker Thiel

Volker Thiel

21

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Marcel Alexander Müller

Marcel A Müller

5

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Friedemann Weber

Friedemann Weber

20

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Christian Drosten

27

Christian Drosten

1 reference

30 July 2017

18

Ralf Zimmer

1 reference

30 July 2017

16

Rolf Hilgenfeld

1 reference

30 July 2017

11

Daniela Niemeyer

1 reference

30 July 2017

Julia Schöpf

2

1 reference

30 July 2017

Manfred Kögl

3

1 reference

30 July 2017

Javier Carbajo-Lozoya

6

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30 July 2017

Thorsten Stellberger

7

1 reference

30 July 2017

Ekatarina von Dall'Armi

8

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30 July 2017

Petra Herzog

9

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30 July 2017

Stefan Kallies

10

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30 July 2017

Vanessa Ditt

12

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30 July 2017

Thomas Kuri

13

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30 July 2017

Ksenia Pumpor

15

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30 July 2017

Frank Schwarz

17

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30 July 2017

Imke Steffen

19

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30 July 2017

Georg Herrler

22

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30 July 2017

Heinz-Jürgen Thiel

23

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30 July 2017

Christel Schwegmann-Wessels

24

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30 July 2017

Jürgen Haas

26

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30 July 2017

Albrecht von Brunn

28

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30 July 2017

publication date

27 October 2011

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30 July 2017

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30 July 2017

volume

7

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30 July 2017

issue

10

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30 July 2017

page(s)

e1002331

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Creative Commons Attribution 4.0 International

30 July 2017

copyright license

start time

27 October 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

HEK293

1 reference

Vero C1008

1 reference

Caco-2

1 reference

HRT-18

1 reference

Huh-7

1 reference

Fcwf-4

1 reference

C8166

1 reference

Jurkat

1 reference

plasmid design

1 reference

LUMIER assay

1 reference

reporter system

1 reference

inoculation

1 reference

real-time polymerase chain reaction

1 reference

cytotoxicity assay

1 reference

luciferase assay

1 reference

Cyclophilin inhibitors for the treatment of HCV infection.

cites work

1 reference

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Genomic characterization of severe acute respiratory syndrome-related coronavirus in European bats and classification of coronaviruses based on partial RNA-dependent RNA polymerase gene sequences

5 July 2018

1 reference

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Nsp1 proteins of group I and SARS coronaviruses share structural and functional similarities

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

Molecular aspects of cyclophilins mediating therapeutic actions of their ligands

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

NFAT pulls the strings during CD4+ T helper cell effector functions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

A two-pronged strategy to suppress host protein synthesis by SARS coronavirus Nsp1 protein

5 July 2018

1 reference

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Reverse genetic characterization of the natural genomic deletion in SARS-Coronavirus strain Frankfurt-1 open reading frame 7b reveals an attenuating function of the 7b protein in-vitro and in-vivo

5 July 2018

1 reference

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Coronavirus diversity, phylogeny and interspecies jumping

5 July 2018

1 reference

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Coronaviruses post-SARS: update on replication and pathogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

An experimentally derived confidence score for binary protein-protein interactions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

Generation of recombinant coronaviruses using vaccinia virus as the cloning vector and stable cell lines containing coronaviral replicon RNAs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

Plaque assay for human coronavirus NL63 using human colon carcinoma cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

Genome-wide analysis of protein-protein interactions and involvement of viral proteins in SARS-CoV replication

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

Ontologizer 2.0--a multifunctional tool for GO term enrichment analysis and data exploration

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

Proteomics analysis unravels the functional repertoire of coronavirus nonstructural protein 3.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

Severe acute respiratory syndrome coronavirus nsp1 suppresses host gene expression, including that of type I interferon, in infected cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

The SARS-Coronavirus PLnc domain of nsp3 as a replication/transcription scaffolding protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

The BioGRID Interaction Database: 2008 update

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

CORUM: the comprehensive resource of mammalian protein complexes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

Severe acute respiratory syndrome coronavirus evades antiviral signaling: role of nsp1 and rational design of an attenuated strain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

Coronavirus non-structural protein 1 is a major pathogenicity factor: implications for the rational design of coronavirus vaccines

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

Analysis of intraviral protein-protein interactions of the SARS coronavirus ORFeome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

The importance of bottlenecks in protein networks: correlation with gene essentiality and expression dynamics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

5 July 2018

Review of bats and SARS

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

Construction of a severe acute respiratory syndrome coronavirus infectious cDNA clone and a replicon to study coronavirus RNA synthesis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

Improved scoring of functional groups from gene expression data by decorrelating GO graph structure

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

Inhibition of cytokine gene expression and induction of chemokine genes in non-lymphatic cells infected with SARS coronavirus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

Serum proteomic fingerprints of adult patients with severe acute respiratory syndrome.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

Herpesviral protein networks and their interaction with the human proteome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

Mutagenesis of the murine hepatitis virus nsp1-coding region identifies residues important for protein processing, viral RNA synthesis, and viral replication

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

Cyclophilin B is a functional regulator of hepatitis C virus RNA polymerase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

NFAT proteins: key regulators of T-cell development and function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

Cinanserin is an inhibitor of the 3C-like proteinase of severe acute respiratory syndrome coronavirus and strongly reduces virus replication in vitro

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

High-throughput mapping of a dynamic signaling network in mammalian cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

Automated yeast two-hybrid screening for nuclear receptor-interacting proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

A human in vitro model system for investigating genome-wide host responses to SARS coronavirus infection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

Prolonged disturbances of in vitro cytokine production in patients with severe acute respiratory syndrome (SARS) treated with ribavirin and steroids

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

Interferon alfacon-1 plus corticosteroids in severe acute respiratory syndrome: a preliminary study

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

The severe acute respiratory syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

Human protein reference database as a discovery resource for proteomics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

Reverse genetics with a full-length infectious cDNA of severe acute respiratory syndrome coronavirus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

Transcriptional regulation by calcium, calcineurin, and NFAT

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

Severe acute respiratory syndrome: identification of the etiological agent

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

The Genome sequence of the SARS-associated coronavirus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

High-throughput yeast two-hybrid assays for large-scale protein interaction mapping

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

Gene regulation mediated by calcium signals in T lymphocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

Direct triggering of the type I interferon system by virus infection: activation of a transcription factor complex containing IRF-3 and CBP/p300.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

Human immunodeficiency virus type 1 Gag protein binds to cyclophilins A and B

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

Transcriptional regulation of the IL-2 gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

GATEWAY recombinational cloning: application to the cloning of large numbers of open reading frames or ORFeomes.

5 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002331

Nucleocapsid protein of SARS coronavirus tightly binds to human cyclophilin A.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002331

Characterization of the sialic acid binding activity of transmissible gastroenteritis coronavirus by analysis of haemagglutination-deficient mutants

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203193

10.1371/JOURNAL.PPAT.1002331

28 October 2018

Identifiers

DOI

1 reference

release_snxesuzmjvfynhecu3dldykvni

30 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/snxesuzmjvfynhecu3dldykvni

24 November 2022

mapped directly with Wikidata item

PMC publication ID

3203193

1 reference

30 July 2017

1 reference