(Q37770082)

22 August 2017

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title

Molecular aspects of cyclophilins mediating therapeutic actions of their ligands (English)

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22 August 2017

Andrzej Galat

1

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22 August 2017

Jacqueline Bua

series ordinal

2

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22 August 2017

publication date

4 July 2010

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Cellular and Molecular Life Sciences

22 August 2017

published in

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22 August 2017

volume

67

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22 August 2017

issue

20

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22 August 2017

page(s)

3467-3488

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https://scigraph.springernature.com/pub.10.1007/s00018-010-0437-0

22 August 2017

exact match

0 references

cites work

Cyclosporin A, FK-506, and rapamycin: pharmacologic probes of lymphocyte signal transduction

1 reference

https://api.crossref.org/works/10.1007%2FS00018-010-0437-0

The novel cyclophilin binding compound, sanglifehrin A, disassociates G1 cell cycle arrest from tolerance induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-010-0437-0

Identification of the immunophilins capable of mediating inhibition of signal transduction by cyclosporin A and FK506: roles of calcineurin binding and cellular location

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-010-0437-0

Cyclophilin A-deficient mice are resistant to immunosuppression by cyclosporine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-010-0437-0

A cyclosporin derivative discriminates between extracellular and intracellular cyclophilins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-010-0437-0

Leishmania major parasites express cyclophilin isoforms with an unusual interaction with calcineurin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-010-0437-0

Extracellular cyclophilins contribute to the regulation of inflammatory responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-010-0437-0

Molecular mechanisms of TGF beta receptor-triggered signaling cascades rapidly induced by the calcineurin inhibitors cyclosporin A and FK506

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-010-0437-0

Detailed characterization of a cyclophilin from the human malaria parasite Plasmodium falciparum

21 January 2018

2 references

https://api.crossref.org/works/10.1007%2FS00018-010-0437-0

21 January 2018

12 December 2020

A CD8 T cell-intrinsic role for the calcineurin-NFAT pathway for tolerance induction in vivo.

1 reference

12 December 2020

Host cell factors in HIV replication: meta-analysis of genome-wide studies

1 reference

12 December 2020

The mitochondrial permeability transition as a target for neuroprotection

1 reference

12 December 2020

Chaperone activity of Cyp18 through hydrophobic condensation that enables rescue of transient misfolded molten globule intermediates

1 reference

12 December 2020

Lack of abundance of cytoplasmic cyclosporin A-binding protein renders free-living Leishmania donovani resistant to cyclosporin A.

1 reference

12 December 2020

Inhibitory effects of Actinidia polygama extract and cyclosporine A on OVA-induced eosinophilia and bronchial hyperresponsiveness in a murine model of asthma

1 reference

12 December 2020

Pharmacological targeting of catalyzed protein folding: the example of peptide bond cis/trans isomerases.

1 reference

12 December 2020

Crystal structure of a complex between human spliceosomal cyclophilin H and a U4/U6 snRNP-60K peptide

1 reference

12 December 2020

Molecular determinants of a native-state prolyl isomerization

1 reference

12 December 2020

A large intrinsically disordered region in SKIP and its disorder-order transition induced by PPIL1 binding revealed by NMR

1 reference

12 December 2020

Stalling of spliceosome assembly at distinct stages by small-molecule inhibitors of protein acetylation and deacetylation

1 reference

12 December 2020

Many sequence variants affecting diversity of adult human height

1 reference

12 December 2020

Interleukin-8 is a cyclosporin A binding protein

1 reference

12 December 2020

Severe osteogenesis imperfecta in cyclophilin B-deficient mice

1 reference

12 December 2020

Crystal structure of human calcineurin complexed with cyclosporin A and human cyclophilin

1 reference

12 December 2020

A novel class of dual-family immunophilins

1 reference

12 December 2020

Cyclosporin analogs inhibit in vitro growth of Cryptosporidium parvum

1 reference

12 December 2020

A large-scale processing of kinetic data files with derivation of the inhibitory constant Ki: an application to proline isomerases

1 reference

12 December 2020

Global, in vivo, and site-specific phosphorylation dynamics in signaling networks

1 reference

12 December 2020

Recombinant cyclophilins lack nuclease activity.

1 reference

12 December 2020

Cyclosporine and analogues: structural requirements for immunosuppressive activity

1 reference

12 December 2020

Cyclolinopeptide A (CLA) mediates its immunosuppressive activity through cyclophilin-dependent calcineurin inactivation

1 reference

12 December 2020

Host-cell cyclophilin is important for the intracellular replication of Leishmania major

1 reference

12 December 2020

Isolation and characterization of a 40-kDa cyclophilin-related protein

1 reference

12 December 2020

Human macrophage migration inhibitory factor: a proven immunomodulatory cytokine?

1 reference

12 December 2020

Cyclophilin-B is an abundant protein whose conformation is similar to cyclophilin-A.

1 reference

12 December 2020

On transversal hydrophobicity of some proteins and their modules.

1 reference

12 December 2020

Cyclophilin A is required for CXCR4-mediated nuclear export of heterogeneous nuclear ribonucleoprotein A2, activation and nuclear translocation of ERK1/2, and chemotactic cell migration

1 reference

12 December 2020

The prolyl cis/trans isomerase cyclophilin 18 interacts with the tumor suppressor p53 and modifies its functions in cell cycle regulation and apoptosis.

1 reference

12 December 2020

Structural insights into the catalytic mechanism of cyclophilin A

1 reference

12 December 2020

Naturally occurring capsid substitutions render HIV-1 cyclophilin A independent in human cells and TRIM-cyclophilin-resistant in Owl monkey cells

1 reference

12 December 2020

Removal of arginine 332 allows human TRIM5alpha to bind human immunodeficiency virus capsids and to restrict infection

1 reference

12 December 2020

Comparative binding studies of cyclophilins to cyclosporin A and derivatives by fluorescence measurements

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12 December 2020

Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha

1 reference

12 December 2020

Cymbimicin A and B, two novel cyclophilin-binding structures isolated from actinomycetes.

1 reference

12 December 2020

Cyclophilin: a specific cytosolic binding protein for cyclosporin A

1 reference

12 December 2020

The spliceosome: design principles of a dynamic RNP machine

1 reference

12 December 2020

Cyclophilins contribute to Stat3 signaling and survival of multiple myeloma cells

1 reference

12 December 2020

Amino acid residues of Leishmania donovani cyclophilin key to interaction with its adenosine kinase: biological implications.

1 reference

12 December 2020

Enhancing the effect of secreted cyclophilin B on immunosuppressive activity of cyclosporine

1 reference

12 December 2020

Structure of human cyclophilin A in complex with the novel immunosuppressant sanglifehrin A at 1.6 A resolution

1 reference

12 December 2020

Cyclosporine Inhibits a Direct Interaction between Cyclophilins and Hepatitis C NS5A

1 reference

12 December 2020

A remote prolyl isomerization controls domain assembly via a hydrogen bonding network

1 reference

12 December 2020

Cyclosporine A treatment for Ullrich congenital muscular dystrophy: a cellular study of mitochondrial dysfunction and its rescue

1 reference

12 December 2020

Cis-trans isomerization at a proline opens the pore of a neurotransmitter-gated ion channel.

1 reference

12 December 2020

Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

1 reference

12 December 2020

Hydration changes implicated in the remarkable temperature-dependent membrane permeation of cyclosporin A.

1 reference

12 December 2020

Specific incorporation of cyclophilin A into HIV-1 virions

1 reference

12 December 2020

The African trypanosome cyclophilin A homologue contains unusual conserved central and N-terminal domains and is developmentally regulated

1 reference

12 December 2020

The worldwide Protein Data Bank (wwPDB): ensuring a single, uniform archive of PDB data

1 reference

12 December 2020

Mitochondrial permeability transition pore opening during myocardial reperfusion--a target for cardioprotection

1 reference

12 December 2020

Cyclophilin A regulates TCR signal strength in CD4+ T cells via a proline-directed conformational switch in Itk.

1 reference

12 December 2020

The binding of cyclosporin A to human plasma: an in vitro microdialysis study

1 reference

12 December 2020

Cyclosporins: structure-activity relationships for the inhibition of the human FPR1 formylpeptide receptor

1 reference

12 December 2020

Regulatory T Cells and T Cell Depletion: Role of Immunosuppressive Drugs

1 reference

12 December 2020

Morpheus unbound: reimagining the morphogen gradient

1 reference

12 December 2020

Isolation, characterization and targeted disruption of mouse ppia: cyclophilin A is not essential for mammalian cell viability

1 reference

12 December 2020

Cunning factor: macrophage migration inhibitory factor as a redox-regulated target

1 reference

12 December 2020

A novel leucine-rich repeat protein (LRR-1): potential involvement in 4-1BB-mediated signal transduction

1 reference

12 December 2020

Cyclophilin C-associated protein (CyCAP) knock-out mice spontaneously develop colonic mucosal hyperplasia and exaggerated tumorigenesis after treatment with carcinogen azoxymethane

1 reference

12 December 2020

Cyclosporin analogs modified in the 3,7,8-positions: substituent effects on peptidylprolyl isomerase inhibition and immunosuppressive activity are nonadditive

1 reference

12 December 2020

Peptidyl-prolyl cis-trans isomerases (immunophilins) and their roles in parasite biochemistry, host-parasite interaction and antiparasitic drug action

1 reference

12 December 2020

Cyclosporins: structure-activity relationships for the inhibition of the human MDR1 P-glycoprotein ABC transporter

1 reference

12 December 2020

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

1 reference

12 December 2020

Anti-Trypanosoma cruzi effects of cyclosporin A derivatives: possible role of a P-glycoprotein and parasite cyclophilins

1 reference

12 December 2020

Cyclophilin A binds to linear peptide motifs containing a consensus that is present in many human proteins

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12 December 2020

In situ detection of cyclosporin A: evidence for nuclear localization of cyclosporine and cyclophilins.

1 reference

12 December 2020

Secreted cyclophilin A, a peptidylprolyl cis-trans isomerase, mediates matrix assembly of hensin, a protein implicated in epithelial differentiation.

1 reference

12 December 2020

A novel and functional interaction between cyclophilin A and prolactin receptor

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12 December 2020

Calcium signalling in T cells stimulated by a cyclophilin B-binding protein

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12 December 2020

Positional cloning identifies a novel cyclophilin as a candidate amplified oncogene in 1q21.

1 reference

12 December 2020

Cyclophilin A regulates HIV-1 infectivity, as demonstrated by gene targeting in human T cells

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12 December 2020

A cyclophilin functions in pre-mRNA splicing

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12 December 2020

Identification of calcium-modulating cyclophilin ligand as a human host restriction to HIV-1 release overcome by Vpu.

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12 December 2020

Interaction of the Hsp90 cochaperone cyclophilin 40 with Hsc70

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12 December 2020

Mitochondrial targeting of cyclosporin A enables selective inhibition of cyclophilin-D and enhanced cytoprotection after glucose and oxygen deprivation

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12 December 2020

Crystal structure implies that cyclophilin predominantly catalyzes the trans to cis isomerization

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12 December 2020

The X-ray structure of a tetrapeptide bound to the active site of human cyclophilin A

1 reference

12 December 2020

An ent-kaurene that inhibits mitotic chromosome movement and binds the kinetochore protein ran-binding protein 2.

1 reference

12 December 2020

Two cytoplasmic candidates for immunophilin action are revealed by affinity for a new cyclophilin: one in the presence and one in the absence of CsA

1 reference

12 December 2020

Targeting calcineurin activation as a therapeutic strategy for T-cell acute lymphoblastic leukemia

1 reference

12 December 2020

Crystal structure of recombinant human T-cell cyclophilin A at 2.5 A resolution

1 reference

12 December 2020

Cyclosporin A inhibits calcineurin (phosphatase 2B) and P-glycoprotein activity in Entamoeba histolytica

1 reference

12 December 2020

Sanglifehrins A, B, C and D, novel cyclophilin-binding compounds isolated from Streptomyces sp. A92-308110. I. Taxonomy, fermentation, isolation and biological activity.

1 reference

12 December 2020

Two protein-protein interaction sites on the spliceosome-associated human cyclophilin CypH

1 reference

12 December 2020

Analysis of the Trypanosoma cruzi cyclophilin gene family and identification of Cyclosporin A binding proteins.

1 reference

12 December 2020

Sanglifehrins A, B, C and D, novel cyclophilin-binding compounds isolated from Streptomyces sp. A92-308110. II. Structure elucidation, stereochemistry and physico-chemical properties

1 reference

12 December 2020

A diversified family of 12-kDa proteins with a high amino acid sequence similarity to macrophage migration-inhibitory factor (MIF).

1 reference

12 December 2020

Signatures of mutation and selection in the cancer genome

1 reference

12 December 2020

Hexokinase II detachment from mitochondria triggers apoptosis through the permeability transition pore independent of voltage-dependent anion channels

1 reference

12 December 2020

Substrate specificities of the peptidyl prolyl cis-trans isomerase activities of cyclophilin and FK-506 binding protein: evidence for the existence of a family of distinct enzymes

1 reference

12 December 2020

Genetic and pharmacologic inhibition of mitochondrial-dependent necrosis attenuates muscular dystrophy

1 reference

12 December 2020

Association of cyclophilin A with renal brush border membranes: redistribution by cyclosporine A

1 reference

12 December 2020

Mode of action of SDZ NIM 811, a nonimmunosuppressive cyclosporin A analog with activity against human immunodeficiency virus (HIV) type 1: interference with HIV protein-cyclophilin A interactions

1 reference

12 December 2020

X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex

1 reference

12 December 2020

Selective assay for CyPA and CyPB in human blood using highly specific anti-peptide antibodies

1 reference

12 December 2020

Physiologically based pharmacokinetic study on a cyclosporin derivative, SDZ IMM 125

1 reference

12 December 2020

Receptor-induced conformation change of the immunosuppressant cyclosporin A.

1 reference

12 December 2020

Bax-mediated mitochondrial outer membrane permeabilization (MOMP), distinct from the mitochondrial permeability transition, is a key mechanism in diclofenac-induced hepatocyte injury: Multiple protective roles of cyclosporin A.

1 reference

12 December 2020

Crystal structure of cyclophilin A complexed with a binding site peptide from the HIV-1 capsid protein

1 reference

12 December 2020

The human TRPV6 channel protein is associated with cyclophilin B in human placenta

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12 December 2020

Potent inhibition of HIV-1 by TRIM5-cyclophilin fusion proteins engineered from human components

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12 December 2020

Cyclophilin A participates in the nuclear translocation of apoptosis-inducing factor in neurons after cerebral hypoxia-ischemia

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12 December 2020

Functional drift of sequence attributes in the FK506-binding proteins (FKBPs).

1 reference

12 December 2020

In vitro anti-parasitic activity of Cyclosporin A analogs on Trypanosoma cruzi

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12 December 2020

Calcium-modulating cyclophilin ligand does not restrict retrovirus release.

1 reference

12 December 2020

Three-dimensional structure and actions of immunosuppressants and their immunophilins

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12 December 2020

The history of cyclosporin A (Sandimmune) revisited: another point of view

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12 December 2020

Crystal structures of cyclophilin and its partners

1 reference

12 December 2020

A nonessential role for Arg 55 in cyclophilin18 for catalysis of proline isomerization during protein folding

1 reference

12 December 2020

Complex landscapes of somatic rearrangement in human breast cancer genomes

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12 December 2020

Influence of proline residues on protein conformation

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12 December 2020

Peptidyl-prolyl isomerase inhibitors

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12 December 2020

Structure of human cyclophilin and its binding site for cyclosporin A determined by X-ray crystallography and NMR spectroscopy

1 reference

12 December 2020

Interaction with glycosaminoglycans is required for cyclophilin B to trigger integrin-mediated adhesion of peripheral blood T lymphocytes to extracellular matrix

1 reference

12 December 2020

Identification of host proteins required for HIV infection through a functional genomic screen

1 reference

12 December 2020

A nuclear RNA-binding cyclophilin in human T cells

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12 December 2020

The mitochondrial permeability transition in neurologic disease

1 reference

12 December 2020

Cloning and characterization of Giardia intestinalis cyclophilin

1 reference

12 December 2020

Inhibition of HIV-1 infection by a CCR5-binding cyclophilin from Toxoplasma gondii

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12 December 2020

Active site mutants of human cyclophilin A separate peptidyl-prolyl isomerase activity from cyclosporin A binding and calcineurin inhibition

1 reference

12 December 2020

Crystal structure of calcineurin-cyclophilin-cyclosporin shows common but distinct recognition of immunophilin-drug complexes

1 reference

12 December 2020

Database resources of the National Center for Biotechnology

1 reference

12 December 2020

Cloning, characterization and functional expression of a cyclophilin of Entamoeba histolytica

1 reference

12 December 2020

Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease

1 reference

12 December 2020

Gel free analysis of the proteome of intracellular Leishmania mexicana

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12 December 2020

Crystal structure of human cyclophilin A bound to the amino-terminal domain of HIV-1 capsid

1 reference

12 December 2020

Molecular and Biochemical Characterization of a Plasmodium Falciparum Cyclophilin Containing a Cleavable Signal Sequence

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12 December 2020

The human nuclear SRcyp is a cell cycle-regulated cyclophilin

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12 December 2020

Cloning and characterization of a Plasmodium falciparum cyclophilin gene that is stage-specifically expressed

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12 December 2020

Sourcing a chemical succession for cyclosporin from parasites and human pathogens

1 reference

12 December 2020

Human cellular restriction factors that target HIV-1 replication

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12 December 2020

Structural, Biochemical, and in Vivo Characterization of the First Virally Encoded Cyclophilin from the Mimivirus

1 reference

12 December 2020

Human cyclophilin C: primary structure, tissue distribution, and determination of binding specificity for cyclosporins

1 reference

12 December 2020

In vitro and in vivo characterization on amorphous solid dispersion of cyclosporine A for inhalation therapy

1 reference

12 December 2020

Human RNPS1 and its associated factors: a versatile alternative pre-mRNA splicing regulator in vivo

1 reference

12 December 2020

Plasmodium falciparum calcineurin and its association with heat shock protein 90: mechanisms for the antimalarial activity of cyclosporin A and synergism with geldanamycin

1 reference

12 December 2020

Isolation, cDNA sequences, and biochemical characterization of the major cyclosporin-binding proteins of Toxoplasma gondii

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12 December 2020

Mechanism of resistance of hepatitis C virus replicons to structurally distinct cyclophilin inhibitors

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12 December 2020

Life span extension and reduced neuronal death after weekly intraventricular cyclosporin injections in the G93A transgenic mouse model of amyotrophic lateral sclerosis

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12 December 2020

Prolyl isomerases do not catalyze isomerization of non-prolyl peptide bonds

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12 December 2020

Genetic analysis of the mammalian transforming growth factor-beta superfamily

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12 December 2020

Overexpression of peptidyl-prolyl isomerase-like 1 is associated with the growth of colon cancer cells

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12 December 2020

Function-dependent clustering of orthologues and paralogues of cyclophilins

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12 December 2020

Evidence for a functional receptor for cyclosporin A on the surface of lymphocytes

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12 December 2020

Plunder and stowaways: incorporation of cellular proteins by enveloped viruses

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12 December 2020

mRNA processing in the Trypanosomatidae

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12 December 2020

In silico analysis of the cyclophilin repertoire of apicomplexan parasites

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12 December 2020

Role of lipoproteins in the plasma binding of SDZ PSC 833, a novel multidrug resistance-reversing cyclosporin

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12 December 2020

Cyclophilin inhibitors

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12 December 2020

The multidrug resistance modulator valspodar (PSC 833) is metabolized by human cytochrome P450 3A. Implications for drug-drug interactions and pharmacological activity of the main metabolite

1 reference

12 December 2020

Biological effects of cyclosporin A: a new antilymphocytic agent. 1976.

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12 December 2020

Sanglifehrin a blocks key dendritic cell functions in vivo and promotes long-term allograft survival together with low-dose CsA

1 reference

12 December 2020

Protein profiles of medulloblastoma cell lines DAOY and D283: identification of tumor-related proteins and principles

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12 December 2020

Lack of cyclophilin B in osteogenesis imperfecta with normal collagen folding

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12 December 2020

Conformational polymorphism of cyclosporin A

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12 December 2020

The crystal structure of human WD40 repeat-containing peptidylprolyl isomerase (PPWD1)

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12 December 2020

A calcium-dependent nuclease from apoptotic rat thymocytes is homologous with cyclophilin. Recombinant cyclophilins A, B, and C have nuclease activity

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12 December 2020

Mechanism of enzymatic and nonenzymatic prolyl cis-trans isomerization.

1 reference

12 December 2020

Involvement of some large immunophilins and their ligands in the protection and regeneration of neurons: a hypothetical mode of action

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12 December 2020

Characterization of anti-Toxoplasma activity of SDZ 215-918, a cyclosporin derivative lacking immunosuppressive and peptidyl-prolyl-isomerase-inhibiting activity: possible role of a P glycoprotein in Toxoplasma physiology

1 reference

12 December 2020

X-ray structure of a monomeric cyclophilin A-cyclosporin A crystal complex at 2.1 A resolution

1 reference

12 December 2020

Sanglifehrins A, B, C and D, Novel Cyclophilin-binding Compounds Isolated from Streptomyces sp. A92-308110. I. Taxonomy, Fermentation, Isolation and Biological Activity.

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.52.466

Identifiers

DOI

10.1007/S00018-010-0437-0

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22 August 2017

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