(Q34067100)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17522595%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

title

Identification of novel CYP2A6*1B variants: the CYP2A6*1B allele is associated with faster in vivo nicotine metabolism (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17522595%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

0 references

7

1 reference

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31 December 2019

4

R E Krasnow

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17522595%20AND%20SRC:MED&resulttype=core&format=json

Christina N Lessov-Schlaggar

31 December 2019

series ordinal

2

object named as

C N Lessov-Schlaggar

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17522595%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

5

G E Swan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17522595%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

6

N L Benowitz

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17522595%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

author name string

J C Mwenifumbo

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17522595%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Q Zhou

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17522595%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

language of work or name

English

0 references

publication date

23 May 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17522595%20AND%20SRC:MED&resulttype=core&format=json

Clinical Pharmacology & Therapeutics

31 December 2019

published in

1 reference

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31 December 2019

volume

83

1 reference

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31 December 2019

issue

1

1 reference

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31 December 2019

page(s)

115-121

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17522595%20AND%20SRC:MED&resulttype=core&format=json

Female sex and oral contraceptive use accelerate nicotine metabolism

31 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921956

Pharmacogenetics of nicotine metabolism in twins: methods and procedures.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921956

Interplay between hnRNP A1 and a cis-acting element in the 3' UTR of CYP2A5 mRNA is central for high expression of the gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921956

Organization, structure and evolution of the CYP2 gene cluster on human chromosome 19.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921956

Identification of a single nucleotide polymorphism in the TATA box of the CYP2A6 gene: impairment of its promoter activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921956

Structural characterization of a new variant of the CYP2A6 gene (CYP2A6*1B) apparently diagnosed as heterozygotes of CYP2A6*1A and CYP2A6*4C.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921956

Duplications and defects in the CYP2A6 gene: identification, genotyping, and in vivo effects on smoking

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921956

Evidence for cytochrome P450 2A6 and 3A4 as major catalysts for N'-nitrosonornicotine alpha-hydroxylation by human liver microsomes.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921956

Retrovirus-mediated stable expression of human CYP2A6 in mammalian cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921956

A genetic polymorphism in coumarin 7-hydroxylation: sequence of the human CYP2A genes and identification of variant CYP2A6 alleles

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921956

Nicotine renal excretion rate influences nicotine intake during cigarette smoking

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921956

Drug therapy. Pharmacologic aspects of cigarette smoking and nicotine addiction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921956

Identification of the human liver cytochrome P-450 responsible for coumarin 7-hydroxylase activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921956

Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921956

Metabolic profile of nicotine in subjects whose CYP2A6 gene is deleted

5 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100246

Nicotine metabolite ratio as an index of cytochrome P450 2A6 metabolic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100246

A novel mutant allele of the CYP2A6 gene (CYP2A6*11 ) found in a cancer patient who showed poor metabolic phenotype towards tegafur

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100246

Impact of CYP2A6 genotype on pretreatment smoking behaviour and nicotine levels from and usage of nicotine replacement therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100246

Ethnic variation in CYP2A6 and association of genetically slow nicotine metabolism and smoking in adult Caucasians.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100246

CYP2A6 genotype and the metabolism and disposition kinetics of nicotine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100246

3'-UTR polymorphism in the human CYP2A6 gene affects mRNA stability and enzyme expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100246

Identification and characterisation of novel polymorphisms in the CYP2A locus: implications for nicotine metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100246

An in vivo pilot study characterizing the new CYP2A6*7, *8, and *10 alleles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100246

CYP2A6 polymorphisms in Malays, Chinese and Indians.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100246

Interaction of heterogeneous nuclear ribonucleoprotein A1 with cytochrome P450 2A6 mRNA: implications for post-transcriptional regulation of the CYP2A6 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100246

CYP2A6 genetic polymorphisms and correlation with smoking status in Brazilians.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100246

Whole deletion of CYP2A6 gene (CYP2A6AST;4C) and smoking behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100246

Inter-gene correlation on oligonucleotide arrays: how much does normalization matter?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100246

Maximum Likelihood Estimation of Misspecified Models

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100246

CYP2A6, MAOA, DBH, DRD4, and 5HT2A genotypes, smoking behaviour and cotinine levels in 1518 UK adolescents

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921956

Nicotine metabolism: the impact of CYP2A6 on estimates of additive genetic influence

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921956

Genetic polymorphism of CYP2A6 gene and tobacco-induced lung cancer risk in male smokers

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921956

A major role for CYP2A6 in nicotine C-oxidation by human liver microsomes.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921956

Metabolism of nicotine to cotinine studied by a dual stable isotope method.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921956

In vivo Evaluation of Coumarin and Nicotine as Probe Drugs to Predict the Metabolic Capacity of CYP2A6 Due to Genetic Polymorphism in Thais

28 October 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100246

Bioactivation of tegafur to 5-fluorouracil is catalyzed by cytochrome P-450 2A6 in human liver microsomes in vitro

21 January 2018

1 reference

12 December 2020

(+)-cis-3,5-dimethyl-2-(3-pyridyl) thiazolidin-4-one hydrochloride (SM-12502) as a novel substrate for cytochrome P450 2A6 in human liver microsomes

1 reference

12 December 2020

Role of human cytochrome P4502A6 in C-oxidation of nicotine

1 reference

12 December 2020

Characterisation and PCR-based detection of a CYP2A6 gene deletion found at a high frequency in a Chinese population

1 reference

12 December 2020

CYP2A6 gene deletion reduces susceptibility to lung cancer

1 reference

12 December 2020

Association of CYP2A6*1B genetic variant with the amount of smoking in French adults from the Stanislas cohort

1 reference

12 December 2020

Determinants of the rate of nicotine metabolism and effects on smoking behavior

1 reference

12 December 2020

CYP2A7 polymorphic alleles confound the genotyping of CYP2A6*4A allele

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.CLPT.6100246

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17522595%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17522595%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

PubMed publication ID

17522595

1 reference