(Q34070940)

30 July 2017

title

American ginseng suppresses Western diet-promoted tumorigenesis in model of inflammation-associated colon cancer: role of EGFR. (English)

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30 July 2017

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12

Eugene B Chang

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30 July 2017

Urszula Dougherty

1

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30 July 2017

Reba Mustafi

2

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30 July 2017

Yunwei Wang

3

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30 July 2017

Mark W Musch

4

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30 July 2017

Chong-Zhi Wang

5

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30 July 2017

Vani J Konda

6

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30 July 2017

Anirudh Kulkarni

7

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30 July 2017

John Hart

8

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30 July 2017

Glyn Dawson

9

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30 July 2017

Karen E Kim

10

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30 July 2017

Chun-Su Yuan

11

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30 July 2017

Marc Bissonnette

13

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30 July 2017

publication date

9 November 2011

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BMC Complementary and Alternative Medicine

30 July 2017

published in

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30 July 2017

volume

11

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30 July 2017

page(s)

111

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Immunopotentiation and antitumor effects of a ginsenoside Rg₃-fortified red ginseng preparation in mice bearing H460 lung cancer cells

30 July 2017

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28 July 2018

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Compound K, a metabolite of ginseng saponin, induces mitochondria-dependent and caspase-dependent apoptosis via the generation of reactive oxygen species in human colon cancer cells

28 July 2018

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28 July 2018

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Intestinal metabolite compound K of ginseng saponin potently attenuates metastatic growth of hepatocellular carcinoma by augmenting apoptosis via a Bid-mediated mitochondrial pathway

28 July 2018

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Regional mucosa-associated microbiota determine physiological expression of TLR2 and TLR4 in murine colon

28 July 2018

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Mechanistic insight into the ability of American ginseng to suppress colon cancer associated with colitis

28 July 2018

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American ginseng: potential structure-function relationship in cancer chemoprevention

28 July 2018

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Compound K, a metabolite of ginseng saponin, induces apoptosis via caspase-8-dependent pathway in HL-60 human leukemia cells

28 July 2018

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Epidermal growth factor receptor is required for colonic tumor promotion by dietary fat in the azoxymethane/dextran sulfate sodium model: roles of transforming growth factor-{alpha} and PTGS2.

28 July 2018

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KG-135, enriched with selected ginsenosides, inhibits the proliferation of human prostate cancer cells in culture and inhibits xenograft growth in athymic mice

28 July 2018

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Role of cyclin inhibitor protein p21 in the inhibition of HCT116 human colon cancer cell proliferation by American ginseng (Panax quinquefolius) and its constituents

28 July 2018

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The mitochondrial pathway is involved in American ginseng-induced apoptosis of SW-480 colon cancer cells

28 July 2018

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Western-style diet-induced colonic tumors and their modulation by calcium and vitamin D in C57Bl/6 mice: a preclinical model for human sporadic colon cancer

28 July 2018

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Dietary induction of colonic tumors in a mouse model of sporadic colon cancer

28 July 2018

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American ginseng suppresses inflammation and DNA damage associated with mouse colitis.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227598

Experimental therapy of prostate cancer with novel natural product anti-cancer ginsenosides

28 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227598

Colorectal carcinogenesis in germ-free and conventionally reared rats: different intestinal environments affect the systemic immunity.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227598

Toll-like receptor-4 promotes the development of colitis-associated colorectal tumors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227598

Red American ginseng: ginsenoside constituents and antiproliferative activities of heat-processed Panax quinquefolius roots

28 July 2018

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Inflammation, cancer, and targets of ginseng

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227598

Perturbations of the AKT signaling pathway in human cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227598

Suppression of colitis-related mouse colon carcinogenesis by a COX-2 inhibitor and PPAR ligands

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227598

Proof of the mysterious efficacy of ginseng: basic and clinical trials: metabolic activation of ginsenoside: deglycosylation by intestinal bacteria and esterification with fatty acid

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227598

Gene mutations and altered gene expression in azoxymethane-induced colon carcinogenesis in rodents

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227598

Transformation of ginseng saponins to ginsenoside Rh2 by acids and human intestinal bacteria and biological activities of their transformants

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227598

A novel inflammation‐related mouse colon carcinogenesis model induced by azoxymethane and dextran sodium sulfate

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227598

Experimental and epidemiological evidence on non-organ specific cancer preventive effect of Korean ginseng and identification of active compounds

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227598

Genetics of dark skin in mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227598

Chemistry and cancer preventing activities of ginseng saponins and some related triterpenoid compounds

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227598

p21 Waf1/Cip1 can protect human colon carcinoma cells against p53-dependent and p53-independent apoptosis induced by natural chemopreventive and therapeutic agents

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227598

Host cyclooxygenase-2 modulates carcinoma growth.

28 July 2018

1 reference

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Antioxidant and anti-tumor promoting activities of the methanol extract of heat-processed ginseng

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227598

Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227598

In vitro antigenotoxic activity of novel ginseng saponin metabolites formed by intestinal bacteria

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227598

An intestinal bacterial metabolite of ginseng protopanaxadiol saponins has the ability to induce apoptosis in tumor cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227598

p21--negative regulator of the cell cycle

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227598

Main ginseng saponin metabolites formed by intestinal bacteria

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227598

G1 delay in cells overexpressing prostaglandin endoperoxide synthase-2.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227598

Clinicopathologic study of dextran sulfate sodium experimental murine colitis.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227598

Statistical methods for the analysis of tumor multiplicity data

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227598

Investigations into the metabolism and mode of action of the colon carcinogens 1,2-dimethylhydrazine and azoxymethane

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227598

Non-organ-specific preventive effect of long-term administration of Korean red ginseng extract on incidence of human cancers.

28 July 2018

1 reference

https://api.crossref.org/works/10.1186%2F1472-6882-11-111

In vitro and in vivo anticancer effects of American ginseng berry: exploring representative compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1472-6882-11-111

Molecular mechanisms underlying anti-tumor promoting activities of heat-processed Panax ginseng C.A. Meyer

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1472-6882-11-111

Ginsenosides inhibit EGF-induced proliferation of renal proximal tubule cells via decrease of c-fos and c-jun gene expression in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1472-6882-11-111

The antimetastatic and immunomodulating activities of ginseng minor glycosides

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1472-6882-11-111

Saponins composition in American ginseng leaf and berry assayed by high-performance liquid chromatography

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1472-6882-11-111

Detection of adulteration of notoginseng root extract with other panax species by quantitative HPLC coupled with PCA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1472-6882-11-111

Prognostic implications of BAX protein expression and microsatellite instability in all non-metastatic stages of primary colon cancer treated by surgery alone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1472-6882-11-111

Ginsenoside Rb1 and its metabolite compound K inhibit IRAK-1 activation--the key step of inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1472-6882-11-111

Characterization of gene expression regulated by American ginseng and ginsenoside Rg3 in human colorectal cancer cells

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227598

Non-organ specific cancer prevention of ginseng: a prospective study in Korea

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227598

Dietary fat and colon cancer: modulating effect of types and amount of dietary fat on ras-p21 function during promotion and progression stages of colon cancer.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227598

Preventive effect of ginseng intake against various human cancers: a case-control study on 1987 pairs

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227598

Intestinal bacterial hydrolysis is required for the appearance of compound K in rat plasma after oral administration of ginsenoside Rb1 from Panax ginseng

28 October 2018

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12 December 2020

High resolution colonoscopy in live mice

1 reference

12 December 2020

Preliminary analysis of azoxymethane induced colon tumors in inbred mice commonly used as transgenic/knockout progenitors

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12 December 2020

Metabolism of 1,2-dimethylhydrazine by cultured rat colon epithelial cells

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12 December 2020

Peroxovanadate induces tyrosine phosphorylation of multiple signaling proteins in mouse liver and kidney

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12 December 2020

Identifiers

DOI

10.1186/1472-6882-11-111

1 reference

Dimensions Publication ID

30 July 2017

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1 reference

30 July 2017

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