(Q34074765)

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Neuronal expression of the transcription factor Gli1 using the Talpha1 alpha-tubulin promoter is neuroprotective in an experimental model of Parkinson's disease.

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5 January 2020

Neuronal expression of the transcription factor Gli1 using the Talpha1 alpha-tubulin promoter is neuroprotective in an experimental model of Parkinson's disease (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15573088%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Parkinson's disease

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based on heuristic

inferred from title

Maria G. Castro

7

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Europe PubMed Central

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5 January 2020

author name string

D Suwelack

1

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5 January 2020

A Hurtado-Lorenzo

2

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5 January 2020

E Millan

3

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5 January 2020

V Gonzalez-Nicolini

4

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5 January 2020

K Wawrowsky

5

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5 January 2020

P R Lowenstein

6

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5 January 2020

publication date

1 December 2004

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5 January 2020

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15573088%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

11

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5 January 2020

24

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5 January 2020

1742-1752

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Europe PubMed Central

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5 January 2020

https://scigraph.springernature.com/pub.10.1038/sj.gt.3302377

0 references

Differentiation and transcription factor gene therapy in experimental parkinson's disease: sonic hedgehog and Gli-1, but not Nurr-1, protect nigrostriatal cell bodies from 6-OHDA-induced neurodegeneration.

1 reference

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5 July 2018

Elevated GDNF levels following viral vector-mediated gene transfer can increase neuronal death after stroke in rats.

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5 July 2018

Sonic hedgehog is a neuromodulator in the adult subthalamic nucleus.

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5 July 2018

Gene therapy progress and prospects: Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1249480

5 July 2018

Neuroprotective strategies in Parkinson's disease : an update on progress

1 reference

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5 July 2018

Sonic hedgehog and FGF8 collaborate to induce dopaminergic phenotypes in the Nurr1-overexpressing neural stem cell

1 reference

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5 July 2018

Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease

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5 July 2018

Long-term striatal overexpression of GDNF selectively downregulates tyrosine hydroxylase in the intact nigrostriatal dopamine system

1 reference

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5 July 2018

Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo

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5 July 2018

Aberrant sprouting and downregulation of tyrosine hydroxylase in lesioned nigrostriatal dopamine neurons induced by long-lasting overexpression of glial cell line derived neurotrophic factor in the striatum by lentiviral gene transfer

1 reference

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5 July 2018

Behavioural and immunohistochemical changes following supranigral administration of sonic hedgehog in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated common marmosets.

1 reference

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5 July 2018

Hedgehog-Gli signalling and the growth of the brain.

1 reference

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5 July 2018

Intrastriatal injection of sonic hedgehog reduces behavioral impairment in a rat model of Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1249480

5 July 2018

Gene therapy for Parkinson's disease: recent achievements and remaining challenges.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1249480

5 July 2018

Regulatable and cell-type specific transgene expression in glial cells: prospects for gene therapy for neurological disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1249480

5 July 2018

Sonic hedgehog facilitates dopamine differentiation in the presence of a mesencephalic glial cell line.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1249480

5 July 2018

Towards a neuroprotective gene therapy for Parkinson's disease: use of adenovirus, AAV and lentivirus vectors for gene transfer of GDNF to the nigrostriatal system in the rat Parkinson model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1249480

5 July 2018

Transducing the hedgehog signal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1249480

5 July 2018

Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1249480

5 July 2018

Transcriptional targeting to anterior pituitary lactotrophic cells using recombinant adenovirus vectors in vitro and in vivo in normal and estrogen/sulpiride-induced hyperplastic anterior pituitaries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1249480

5 July 2018

Long-term rAAV-mediated gene transfer of GDNF in the rat Parkinson's model: intrastriatal but not intranigral transduction promotes functional regeneration in the lesioned nigrostriatal system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1249480

5 July 2018

Peripheral infection with adenovirus causes unexpected long-term brain inflammation in animals injected intracranially with first-generation, but not with high-capacity, adenovirus vectors: toward realistic long-term neurological gene therapy for ch

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1249480

5 July 2018

Adenovirus-mediated herpes simplex virus type-1 thymidine kinase gene therapy suppresses oestrogen-induced pituitary prolactinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1249480

5 July 2018

Nurr1, an orphan nuclear receptor, is a transcriptional activator of endogenous tyrosine hydroxylase in neural progenitor cells derived from the adult brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1249480

5 July 2018

Regional distribution of Sonic Hedgehog, patched, and smoothened mRNA in the adult rat brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1249480

5 July 2018

Dorsoventral patterning and oligodendroglial specification in the developing central nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1249480

5 July 2018

Gli1 is a target of Sonic hedgehog that induces ventral neural tube development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1249480

5 July 2018

A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1249480

5 July 2018

Dopamine neuron agenesis in Nurr1-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1249480

5 July 2018

Dopaminergic neurons protected from degeneration by GDNF gene therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1249480

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GDNF selectively protects dopamine neurons over serotonin neurons against the neurotoxic effects of methamphetamine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1249480

5 July 2018

Comparison of the expression of a T alpha 1:nlacZ transgene and T alpha 1 alpha-tubulin mRNA in the mature central nervous system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1249480

5 July 2018

Supernatant rescue assay vs. polymerase chain reaction for detection of wild type adenovirus-contaminating recombinant adenovirus stocks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1249480

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Expression of three mouse homologs of the Drosophila segment polarity gene cubitus interruptus, Gli, Gli-2, and Gli-3, in ectoderm- and mesoderm-derived tissues suggests multiple roles during postimplantation development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1249480

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The T alpha 1 alpha-tubulin promoter specifies gene expression as a function of neuronal growth and regeneration in transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1249480

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Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator

1 reference

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Induction of midbrain dopaminergic neurons by Sonic hedgehog

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302377

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Expression of the mouse Gli and Ptc genes is adjacent to embryonic sources of hedgehog signals suggesting a conservation of pathways between flies and mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302377

21 January 2018

Sonic Hedgehog signalling in the developing and adult brain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302377

21 January 2018

Discrete localizations of hedgehog signalling components in the developing and adult rat nervous system.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302377

21 January 2018

Cell-type-specific and regulatable transgenesis in the adult brain: adenovirus-encoded combined transcriptional targeting and inducible transgene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302377

21 January 2018

Cell type-specific expression in brain cell cultures from a short human cytomegalovirus major immediate early promoter depends on whether it is inserted into herpesvirus or adenovirus vectors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302377

21 January 2018

Acute direct adenoviral vector cytotoxicity and chronic, but not acute, inflammatory responses correlate with decreased vector-mediated transgene expression in the brain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302377

21 January 2018

Preexisting antiadenoviral immunity is not a barrier to efficient and stable transduction of the brain, mediated by novel high-capacity adenovirus vectors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302377

21 January 2018

Neuron-specific expression of therapeutic proteins: evaluation of different cellular promoters in recombinant adenoviral vectors.

1 reference

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21 January 2018

Induction of T alpha 1 alpha-tubulin mRNA during neuronal regeneration is a function of the amount of axon lost.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302377

21 January 2018

Towards global and long-term neurological gene therapy: unexpected transgene dependent, high-level, and widespread distribution of HSV-1 thymidine kinase throughout the CNS.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302377

21 January 2018

Cell type-specific adenoviral transgene expression in the intact ovine pituitary gland after stereotaxic delivery: an in vivo system for long-term multiple parameter evaluation of human pituitary gene therapy.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302377

21 January 2018

Strong promoters are the key to highly efficient, noninflammatory and noncytotoxic adenoviral-mediated transgene delivery into the brain in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302377

21 January 2018

Sonic hedgehog promotes the survival of specific CNS neuron populations and protects these cells from toxic insult In vitro

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SJ.GT.3302377

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15573088%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15573088%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15573088%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

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