(Q34079306)

30 July 2017

title

Galectin-3 mediates cross-talk between K-Ras and Let-7c tumor suppressor microRNA (English)

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30 July 2017

1 reference

Ran Levy

1

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30 July 2017

Anat Biran

2

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30 July 2017

Francoise Poirier

3

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30 July 2017

Avraham Raz

4

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30 July 2017

Yoel Kloog

5

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30 July 2017

language of work or name

English

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publication date

15 November 2011

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30 July 2017

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30 July 2017

volume

6

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30 July 2017

issue

11

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30 July 2017

page(s)

e27490

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Creative Commons Attribution 4.0 International

30 July 2017

copyright license

start time

15 November 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3216962/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Genetic modulation of the Let-7 microRNA binding to KRAS 3'-untranslated region and survival of metastatic colorectal cancer patients treated with salvage cetuximab-irinotecan

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MicroRNA function in cancer: oncogene or a tumor suppressor?

28 July 2018

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The microRNA network and tumor metastasis

28 July 2018

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KRAS mutation, KRAS-LCS6 polymorphism, and non-small cell lung cancer.

28 July 2018

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A let-7 microRNA-binding site polymorphism in the KRAS 3' UTR is associated with reduced survival in oral cancers

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216962

A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk

28 July 2018

1 reference

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K-ras nanoclustering is subverted by overexpression of the scaffold protein galectin-3.

28 July 2018

1 reference

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Suppression of non-small cell lung tumor development by the let-7 microRNA family

28 July 2018

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Distinct functions of H-Ras and K-Ras in proliferation and survival of primary hepatocytes due to selective activation of ERK and PI3K

28 July 2018

1 reference

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let-7 regulates self renewal and tumorigenicity of breast cancer cells

28 July 2018

1 reference

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Let-7 expression defines two differentiation stages of cancer

28 July 2018

1 reference

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On the role of galectins in signal transduction

28 July 2018

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The tumor suppressor neurofibromin confers sensitivity to apoptosis by Ras-dependent and Ras-independent pathways

28 July 2018

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let-7 microRNA functions as a potential growth suppressor in human colon cancer cells

28 July 2018

1 reference

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Galectin-3 regulates a molecular switch from N-Ras to K-Ras usage in human breast carcinoma cells

28 July 2018

1 reference

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Signaling interplay in Ras superfamily function

28 July 2018

1 reference

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Compartmentalized signalling of Ras.

28 July 2018

1 reference

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RAS is regulated by the let-7 microRNA family

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216962

MicroRNAs: small RNAs with a big role in gene regulation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216962

Galectin-3 augments K-Ras activation and triggers a Ras signal that attenuates ERK but not phosphoinositide 3-kinase activity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216962

Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival

28 July 2018

1 reference

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Nuclear export of phosphorylated galectin-3 regulates its antiapoptotic activity in response to chemotherapeutic drugs.

28 July 2018

1 reference

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D4476, a cell-permeant inhibitor of CK1, suppresses the site-specific phosphorylation and nuclear exclusion of FOXO1a.

28 July 2018

1 reference

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Targeting RAS signalling pathways in cancer therapy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216962

Activated K-Ras and H-Ras display different interactions with saturable nonraft sites at the surface of live cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216962

Galectin-3 phosphorylation is required for its anti-apoptotic function and cell cycle arrest

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216962

Membrane interactions of a constitutively active GFP-Ki-Ras 4B and their role in signaling. Evidence from lateral mobility studies.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216962

L-29, a soluble lactose-binding lectin, is phosphorylated on serine 6 and serine 12 in vivo and by casein kinase I.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216962

Galectins: a family of animal beta-galactoside-binding lectins

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216962

The CAAX peptidomimetic compound B581 specifically blocks farnesylated, but not geranylgeranylated or myristylated, oncogenic ras signaling and transformation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216962

Comparative analysis of mutations in the p53 and K-ras genes in pancreatic cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216962

ras oncogenes in human cancer: a review

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216962

Galectin-3 Promotes Chronic Activation of K-Ras and Differentiation Block in Malignant Thyroid Carcinomas

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216962

MicroRNA let-7b targets important cell cycle molecules in malignant melanoma cells and interferes with anchorage-independent growth

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216962

The dark side of Ras: regulation of apoptosis

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216962

Galectins in mouse embryogenesis.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216962

Galectin-1 Augments Ras Activation and Diverts Ras Signals to Raf-1 at the Expense of Phosphoinositide 3-Kinase

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216962

Phosphorylation of the beta-galactoside-binding protein galectin-3 modulates binding to its ligands

9 December 2018

1 reference

12 December 2020

Normal development of mice carrying a null mutation in the gene encoding the L14 S-type lectin

1 reference

12 December 2020

Embryonic implantation in galectin 1/galectin 3 double mutant mice

1 reference

12 December 2020

Stopping ras in its tracks

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0027490

Identifiers

DOI

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30 July 2017

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30 July 2017

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