(Q40210019)

18 September 2017

The tumor suppressor neurofibromin confers sensitivity to apoptosis by Ras-dependent and Ras-independent pathways (English)

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18 September 2017

Shapira S

1

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18 September 2017

Barkan B

2

1 reference

18 September 2017

Friedman E

3

1 reference

18 September 2017

Kloog Y

4

1 reference

18 September 2017

Stein R

5

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18 September 2017

10 November 2006

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Cell Death & Differentiation

18 September 2017

1 reference

18 September 2017

14

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18 September 2017

5

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18 September 2017

895-906

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https://scigraph.springernature.com/pub.10.1038/sj.cdd.4402057

18 September 2017

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cites work

Neurofibromatosis type 1 - a model for nervous system tumour formation?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402057

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402057

Aberrant regulation of ras proteins in malignant tumour cells from type 1 neurofibromatosis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402057

Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402057

Tumour predisposition in mice heterozygous for a targeted mutation in Nf1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402057

Mouse models of tumor development in neurofibromatosis type 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402057

Astrocyte-specific inactivation of the neurofibromatosis 1 gene (NF1) is insufficient for astrocytoma formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402057

A neurofibromatosis-1-regulated pathway is required for learning in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402057

Rescue of a Drosophila NF1 mutant phenotype by protein kinase A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402057

Neurofibromin can inhibit Ras-dependent growth by a mechanism independent of its GTPase-accelerating function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402057

Effect of neurofibromatosis type I mutations on a novel pathway for adenylyl cyclase activation requiring neurofibromin and Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402057

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402057

DAP kinase-a proapoptotic gene that functions as a tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402057

Apoptosis coincident with the differentiation of skeletal myoblasts is delayed by caspase 3 inhibition and abrogated by MEK-independent constitutive Ras signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402057

The dark side of Ras: regulation of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402057

Hyperactivation of protein kinase B and ERK have discrete effects on survival, proliferation, and cytokine expression in Nf1-deficient myeloid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402057

Loss of the nf1 tumor suppressor gene decreases fas antigen expression in myeloid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402057

Dynamic regulation of the Ras pathway via proteolysis of the NF1 tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402057

The NF1 tumor suppressor critically regulates TSC2 and mTOR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402057

Prenyl-binding domains: potential targets for Ras inhibitors and anti-cancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402057

Concepts in Ras-directed therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402057

The Ras inhibitor farnesylthiosalicylic acid as a potential therapy for neurofibromatosis type 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402057

E2F1 identified by promoter and biochemical analysis as a central target of glioblastoma cell-cycle arrest in response to Ras inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402057

Neurofibromin regulates neural stem cell proliferation, survival, and astroglial differentiation in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402057

The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402057

Selective inhibition of Ras-dependent cell growth by farnesylthiosalisylic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402057

Bcl-xS and Bax induce different apoptotic pathways in PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402057

Galectin-1 binds oncogenic H-Ras to mediate Ras membrane anchorage and cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402057

The Neurofibromatosis 1 Gene Product Neurofibromin Regulates Pituitary Adenylate Cyclase-Activating Polypeptide-Mediated Signaling in Astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402057

7 January 2021

p21 ras and phosphatidylinositol-3 kinase are required for survival of wild-type and NF1 mutant sensory neurons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402057

7 January 2021

Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402057

7 January 2021

Transduction of wild-type merlin into human schwannoma cells decreases schwannoma cell growth and induces apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402057

7 January 2021

Inhibition of drug-induced apoptosis by survival factors in PC12 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402057

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4402057

1 reference

Dimensions Publication ID

18 September 2017

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1 reference