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Loss of the nf1 tumor suppressor gene decreases fas antigen expression in myeloid cells
scientific journal article
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instance of
scholarly article
1 reference
stated in
PubMed
PubMed ID
15039234
retrieved
24 January 2017
title
Loss of the nf1 tumor suppressor gene decreases fas antigen expression in myeloid cells
(English)
1 reference
stated in
PubMed
PubMed ID
15039234
retrieved
24 January 2017
main subject
Neurofibromin 1
1 reference
stated in
GOA release 2020-03-11
Kit ligand
1 reference
stated in
GOA release 2020-03-11
Phosphoinositide-3-kinase regulatory subunit 1
1 reference
stated in
GOA release 2020-03-11
Fas (TNF receptor superfamily member 6)
1 reference
stated in
GOA release 2020-03-11
Fas ligand (TNF superfamily, member 6)
1 reference
stated in
GOA release 2020-03-11
author name string
Kelly Hiatt
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
15039234
retrieved
24 January 2017
David A. Ingram
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
15039234
retrieved
24 January 2017
Hannah Huddleston
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
15039234
retrieved
24 January 2017
Dan F. Spandau
series ordinal
4
1 reference
stated in
PubMed
PubMed ID
15039234
retrieved
24 January 2017
Reuben Kapur
series ordinal
5
1 reference
stated in
PubMed
PubMed ID
15039234
retrieved
24 January 2017
D. Wade Clapp
series ordinal
6
1 reference
stated in
PubMed
PubMed ID
15039234
retrieved
24 January 2017
language of work or name
English
0 references
publication date
1 April 2004
1 reference
stated in
PubMed
PubMed ID
15039234
retrieved
24 January 2017
published in
The American Journal of Pathology
1 reference
stated in
PubMed
PubMed ID
15039234
retrieved
24 January 2017
volume
164
1 reference
stated in
PubMed
PubMed ID
15039234
retrieved
24 January 2017
page(s)
1471–1479
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stated in
PubMed
PubMed ID
15039234
retrieved
24 January 2017
issue
4
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stated in
PubMed
PubMed ID
15039234
retrieved
24 January 2017
cites work
Inflammation and cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615352
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19 March 2017
The Fas signaling pathway: more than a paradigm
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615352
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19 March 2017
Hyperactivation of p21(ras) and the hematopoietic-specific Rho GTPase, Rac2, cooperate to alter the proliferation of neurofibromin-deficient mast cells in vivo and in vitro
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615352
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19 March 2017
NF1 tumor suppressor gene function: narrowing the GAP
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615352
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19 March 2017
Genetic and biochemical evidence that haploinsufficiency of the Nf1 tumor suppressor gene modulates melanocyte and mast cell fates in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615352
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19 March 2017
Nf1 deficiency causes Ras-mediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemia
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615352
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19 March 2017
Neurofibromin-deficient Schwann cells secrete a potent migratory stimulus for Nf1+/- mast cells
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PubMed Central
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29 September 2017
The death effector domain protein family: regulators of cellular homeostasis
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PubMed Central
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29 September 2017
Thinking beyond the tumor cell: Nf1 haploinsufficiency in the tumor environment
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615352
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29 September 2017
Neurofibromas in NF1: Schwann cell origin and role of tumor environment
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615352
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29 September 2017
Farnesyltransferase inhibitors reverse Ras-mediated inhibition of Fas gene expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615352
retrieved
29 September 2017
Quantitative effects of Nf1 inactivation on in vivo hematopoiesis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615352
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29 September 2017
Neurofibromin GTPase-activating protein-related domains restore normal growth in Nf1-/- cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615352
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29 September 2017
Combined stimulation with the T helper cell type 2 cytokines interleukin (IL)-4 and IL-10 induces mouse mast cell apoptosis
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615352
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29 September 2017
Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615352
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29 September 2017
Oncogenic Ras inhibits Fas ligand-mediated apoptosis by downregulating the expression of Fas.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615352
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29 September 2017
SHIP is a negative regulator of growth factor receptor-mediated PKB/Akt activation and myeloid cell survival
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615352
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29 September 2017
Selective disactivation of neurofibromin GAP activity in neurofibromatosis type 1.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615352
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29 September 2017
Nf1 regulates hematopoietic progenitor cell growth and ras signaling in response to multiple cytokines
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615352
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29 September 2017
Mutation of CD95 (Fas/Apo-1) gene in adult T-cell leukemia cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615352
retrieved
29 September 2017
Fas (CD95, APO-1) antigen expression and function in murine mast cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615352
retrieved
29 September 2017
Mutations in the Fas antigen in patients with multiple myeloma.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615352
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29 September 2017
Differential roles of PI3-kinase and Kit tyrosine 821 in Kit receptor-mediated proliferation, survival and cell adhesion in mast cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615352
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29 September 2017
The c-kit ligand, stem cell factor, promotes mast cell survival by suppressing apoptosis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615352
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29 September 2017
Type 1 neurofibromatosis gene: identification of a large transcript disrupted in three NF1 patients
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615352
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29 September 2017
The rat c-kit ligand, stem cell factor, induces the development of connective tissue-type and mucosal mast cells in vivo. Analysis by anatomical distribution, histochemistry, and protease phenotype
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615352
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29 September 2017
Deletions and a translocation interrupt a cloned gene at the neurofibromatosis type 1 locus.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615352
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29 September 2017
Monosomy 7 myeloproliferative disease in children with neurofibromatosis, type 1: epidemiology and molecular analysis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615352
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29 September 2017
CD95 (APO-1/Fas) mutations in childhood T-lineage acute lymphoblastic leukemia.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615352
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2 June 2018
Loss of the normal NF1 allele from the bone marrow of children with type 1 neurofibromatosis and malignant myeloid disorders
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615352
retrieved
2 June 2018
Role for the stem cell factor/KIT complex in Schwann cell neoplasia and mast cell proliferation associated with neurofibromatosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615352
retrieved
2 June 2018
Ras regulation. NF is enough of GAP
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615352
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2 June 2018
Leukemic potential of doubly mutant Nf1 and Wv hematopoietic cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615352
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27 November 2018
Inhibition of MEK induces fas expression and apoptosis in lymphomas overexpressing Ras.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615352
retrieved
27 November 2018
Inflammatory cells and cancer: think different!
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615352
retrieved
27 November 2018
Multiple inhibitory cytokines induce deregulated progenitor growth and apoptosis in hematopoietic cells from Fac-/- mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615352
retrieved
27 November 2018
Homozygous inactivation of the NF1 gene in bone marrow cells from children with neurofibromatosis type 1 and malignant myeloid disorders
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615352
retrieved
27 November 2018
Loss of NF1 results in activation of the Ras signaling pathway and leads to aberrant growth in haematopoietic cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615352
retrieved
27 November 2018
Fas ligand (FasL, CD95L, APO-1L) expression in murine mast cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963233-6
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7 January 2021
The NF1 gene in myelopoiesis and childhood myelodysplastic syndromes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963233-6
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7 January 2021
Genetic evidence for convergence of c-Kit- and alpha4 integrin-mediated signals on class IA PI-3kinase and the Rac pathway in regulating integrin-directed migration in mast cells
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963233-6
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7 January 2021
A role for the Fas/Fas ligand apoptotic pathway in regulating myeloid progenitor cell kinetics
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963233-6
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7 January 2021
Increased fetal and extramedullary hematopoiesis in Fas-deficient C57BL/6-lpr/lpr mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/15039234
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Mutations of the ras proto-oncogenes in childhood monosomy 7
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/15039234
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The role of monocyte-derived hemopoietic growth factors in the regulation of myeloproliferation in juvenile chronic myelogenous leukemia
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/15039234
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Possible involvement of c-kit receptor and its ligand in increase of mast cells in neurofibroma tissues
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/15039234
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/S0002-9440(10)63233-6
1 reference
stated in
PubMed
PubMed ID
15039234
retrieved
24 January 2017
PMCID
1615352
0 references
PubMed ID
15039234
1 reference
stated in
PubMed
PubMed ID
15039234
retrieved
24 January 2017
ResearchGate publication ID
8661983
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