(Q35116679)

6 August 2017

1 reference

title

The death effector domain protein family: regulators of cellular homeostasis (English)

1 reference

signal transducing adaptor protein

6 August 2017

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12719729

28 December 2023

1 reference

28 December 2023

author name string

Lixin Zheng

series ordinal

2

1 reference

6 August 2017

Michael D. Tibbetts

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12719729

28 December 2023

Michael J. Lenardo

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12719729

28 December 2023

language of work or name

English

0 references

publication date

1 May 2003

1 reference

full work available at URL

6 August 2017

https://www.nature.com/articles/ni0503-404.pdf

file format

Portable Document Format

1 reference

https://www.nature.com/articles/ni0503-404

28 December 2023

1 reference

28 December 2023

1 reference

6 August 2017

4

1 reference

6 August 2017

404-409

1 reference

6 August 2017

5

1 reference

https://scigraph.springernature.com/pub.10.1038/ni0503-404

6 August 2017

0 references

cites work

A novel domain within the 55 kd TNF receptor signals cell death

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

An induced proximity model for caspase-8 activation.

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

Membrane oligomerization and cleavage activates the caspase-8 (FLICE/MACHalpha1) death signal

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

Caspase-10 is an initiator caspase in death receptor signaling

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

The death domain superfamily: a tale of two interfaces?

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

NMR structure and mutagenesis of the FADD (Mort1) death-effector domain

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

The modular nature of apoptotic signaling proteins

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

The pyrin domain: a possible member of the death domain-fold family implicated in apoptosis and inflammation

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

The CARD domain: a new apoptotic signalling motif

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

Binding of FADD and caspase-8 to molluscum contagiosum virus MC159 v-FLIP is not sufficient for its antiapoptotic function

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

dFADD, a novel death domain-containing adapter protein for the Drosophila caspase DREDD.

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

Death effector domain of a mammalian apoptosis mediator, FADD, induces bacterial cell death

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

Fas preassociation required for apoptosis signaling and dominant inhibition by pathogenic mutations

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

Identification of a basic surface area of the FADD death effector domain critical for apoptotic signaling

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

A docking model of key components of the DISC complex: death domain superfamily interactions redefined

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

Autoproteolytic activation of pro-caspases by oligomerization.

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

Caspase-independent cell death in T lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

Induction of necrotic-like cell death by tumor necrosis factor alpha and caspase inhibitors: novel mechanism for killing virus-infected cells

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

Death effector domain-containing herpesvirus and poxvirus proteins inhibit both Fas- and TNFR1-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

A novel family of viral death effector domain-containing molecules that inhibit both CD-95- and tumor necrosis factor receptor-1-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

The death effector domains (DEDs) of the molluscum contagiosum virus MC159 v-FLIP protein are not functionally interchangeable with each other or with the DEDs of caspase-8.

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

Inhibition of death receptor signals by cellular FLIP

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1- and CD-95-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

NF-kappaB inducers upregulate cFLIP, a cycloheximide-sensitive inhibitor of death receptor signaling

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

NF-kappaB signals induce the expression of c-FLIP.

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

Constitutive expression of c-FLIP in Hodgkin and Reed-Sternberg cells

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

c-FLIP(L) is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

The caspase 8 inhibitor c-FLIP(L) modulates T-cell receptor-induced proliferation but not activation-induced cell death of lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

PED/PEA-15: an anti-apoptotic molecule that regulates FAS/TNFR1-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

Endothelin induces a calcium-dependent phosphorylation of PEA-15 in intact astrocytes: identification of Ser104 and Ser116 phosphorylated, respectively, by protein kinase C and calcium/calmodulin kinase II in vitro

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

Protein kinase C regulates FADD recruitment and death-inducing signaling complex formation in Fas/CD95-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

Tumor necrosis factor-related apoptosis-inducing ligand-induced death-inducing signaling complex and its modulation by c-FLIP and PED/PEA-15 in glioma cells

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

The phosphoprotein protein PEA-15 inhibits Fas- but increases TNF-R1-mediated caspase-8 activity and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

DEDD, a novel death effector domain-containing protein, targeted to the nucleolus

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

Nuclear localization of DEDD leads to caspase-6 activation through its death effector domain and inhibition of RNA polymerase I dependent transcription

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

DEDD regulates degradation of intermediate filaments during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

Identification and characterization of DEDD2, a death effector domain-containing protein

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

The death effector domain-associated factor plays distinct regulatory roles in the nucleus and cytoplasm.

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

p28 Bap31, a Bcl-2/Bcl-XL- and procaspase-8-associated protein in the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

BAR: An apoptosis regulator at the intersection of caspases and Bcl-2 family proteins

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

Inactivation of caspase-8 on mitochondria of Bcl-xL-expressing MCF7-Fas cells: role for the bifunctional apoptosis regulator protein

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

Caspase-resistant BAP31 inhibits fas-mediated apoptotic membrane fragmentation and release of cytochrome c from mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

Uncleaved BAP31 in association with A4 protein at the endoplasmic reticulum is an inhibitor of Fas-initiated release of cytochrome c from mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

Death-effector filaments: novel cytoplasmic structures that recruit caspases and trigger apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

A role for FADD in T cell activation and development

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

Inhibition of caspase or FADD function blocks proliferation but not MAP kinase-activation and interleukin-2-production during primary stimulation of T cells

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

Early activation of caspases during T lymphocyte stimulation results in selective substrate cleavage in nonapoptotic cells

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

Caspase activation is required for T cell proliferation

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

Activation of the NF-kappaB pathway by caspase 8 and its homologs

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

Activation of NF-kappaB by FADD, Casper, and caspase-8.

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

Inherited human Caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

Death effector domain protein PEA-15 potentiates Ras activation of extracellular signal receptor-activated kinase by an adhesion-independent mechanism

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

PEA-15 mediates cytoplasmic sequestration of ERK MAP kinase

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

A stem cell molecular signature

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi

1 reference

https://api.crossref.org/works/10.1038%2FNI0503-404

7 January 2021

Journal of Experimental Medicine

70

178

1891

MR Alderson

1993

1 reference

https://api.fatcat.wiki/v0/release/uihrxhicgvglthh3bf6wes6rqm

28 December 2023

Identifiers

1 reference

30 July 2022

mapped directly with Wikidata item

Dimensions Publication ID

1033332262

0 references

Fatcat ID

release_uihrxhicgvglthh3bf6wes6rqm

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/uihrxhicgvglthh3bf6wes6rqm

30 July 2022

mapped directly with Wikidata item

1 reference

https://api.fatcat.wiki/v0/release/uihrxhicgvglthh3bf6wes6rqm

30 July 2022