(Q34080209)

30 July 2017

title

Disorder-specific effects of polymorphisms at opposing ends of the Insulin Degrading Enzyme gene (English)

1 reference

30 July 2017

1 reference

Claus-Jürgen Scholz

2

0 references

Edna Grünblatt

object named as

Edna Grünblatt

12

0 references

Peter Riederer

11

object named as

Peter Riederer

1 reference

30 July 2017

8

Walter Danielczyk

1 reference

30 July 2017

5

Ildiko Wichart

1 reference

30 July 2017

4

Susanne Jungwirth

1 reference

30 July 2017

1

Jasmin Bartl

1 reference

30 July 2017

author name string

Margareta Hinterberger

3

1 reference

30 July 2017

Michael K Rainer

6

1 reference

30 July 2017

Susanne Kneitz

7

1 reference

30 July 2017

Karl H Tragl

9

1 reference

30 July 2017

Peter Fischer

10

1 reference

30 July 2017

publication date

22 November 2011

1 reference

30 July 2017

1 reference

30 July 2017

volume

12

1 reference

30 July 2017

page(s)

151

1 reference

Concordant association of insulin degrading enzyme gene (IDE) variants with IDE mRNA, Abeta, and Alzheimer's disease

30 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266204

Protective role of Cys-178 against the inactivation and oligomerization of human insulin-degrading enzyme by oxidation and nitrosylation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266204

Promoter polymorphisms which modulate insulin degrading enzyme expression may increase susceptibility to Alzheimer's disease.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266204

Down-regulation of insulin-degrading enzyme by presenilin 1 V97L mutant potentially underlies increased levels of amyloid beta 42.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266204

Decreased catalytic activity of the insulin-degrading enzyme in chromosome 10-linked Alzheimer disease families

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266204

Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266204

beta-Amyloid degradation and Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266204

Mutation screening of a haplotype block around the insulin degrading enzyme gene and association with Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266204

Polymorphisms in the insulin-degrading enzyme gene are associated with type 2 diabetes in men from the NHLBI Framingham Heart Study

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266204

Age at onset in two common neurodegenerative diseases is genetically controlled

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266204

Insulin resistance: cellular and clinical concepts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266204

Insulysin hydrolyzes amyloid beta peptides to products that are neither neurotoxic nor deposit on amyloid plaques.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266204

Genomewide search for type 2 diabetes-susceptibility genes in French whites: evidence for a novel susceptibility locus for early-onset diabetes on chromosome 3q27-qter and independent replication of a type 2-diabetes locus on chromosome 1q21-q24.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266204

The Finland-United States investigation of non-insulin-dependent diabetes mellitus genetics (FUSION) study. I. An autosomal genome scan for genes that predispose to type 2 diabetes.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266204

Insulin-degrading enzyme identified as a candidate diabetes susceptibility gene in GK rats

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266204

Linkage of type 2 diabetes mellitus and of age at onset to a genetic location on chromosome 10q in Mexican Americans

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266204

Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266204

Degradation of Alzheimer's beta-amyloid protein by human and rat brain peptidases: involvement of insulin-degrading enzyme

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266204

Alzheimer's beta-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266204

Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266204

Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266204

Degradation of soluble amyloid beta-peptides 1-40, 1-42, and the Dutch variant 1-40Q by insulin degrading enzyme from Alzheimer disease and control brains.

5 July 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-12-151

Susceptibility locus for Alzheimer's disease on chromosome 10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-12-151

Oxidative stress related markers in the "VITA" and the centenarian projects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-12-151

Quantitative trait loci near the insulin-degrading enzyme (IDE) gene contribute to variation in plasma insulin levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-12-151

Positive association between risk for late-onset Alzheimer disease and genetic variation in IDE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-12-151

Sequence variants of IDE are associated with the extent of beta-amyloid deposition in the Alzheimer's disease brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-12-151

Can enzyme kinetics of prooxidants teach us a lesson about the treatment of Alzheimer's disease: a pilot post-mortem study

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-12-151

Increased activity of mitochondrial aldehyde dehydrogenase (ALDH) in the putamen of individuals with Alzheimer's disease: a human postmortem study

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-12-151

Brain insulin impairs amyloid-beta(1-40) clearance from the brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-12-151

Localization of the gene encoding insulin-degrading enzyme to human chromosome 10, bands q23→q25

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-12-151

Plasma Amyloid Beta-42 Independently Predicts Both Late-Onset Depression and Alzheimer Disease

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266204

Vienna Transdanube Aging "VITA": study design, recruitment strategies and level of participation.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266204

Initiating insulin in patients with type 2 diabetes

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22107728

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Linkage of plasma Abeta42 to a quantitative locus on chromosome 10 in late-onset Alzheimer's disease pedigrees

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22107728

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1471-2350-12-151

1 reference

Dimensions Publication ID

30 July 2017

0 references

1 reference

30 July 2017

1 reference