(Q34095769)

31 July 2017

title

Assessment of Urokinase-Type Plasminogen Activator and Its Inhibitor PAI-1 in Breast Cancer Tissue: Historical Aspects and Future Prospects (English)

1 reference

31 July 2017

1 reference

7

Nadia Harbeck

0 references

author name string

Manfred Schmitt

1

1 reference

31 July 2017

Karin Mengele

2

1 reference

31 July 2017

Apostolos Gkazepis

3

1 reference

31 July 2017

Rudolf Napieralski

4

1 reference

31 July 2017

Viktor Magdolen

5

1 reference

31 July 2017

Ute Reuning

6

1 reference

31 July 2017

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20824007

8 July 2024

publication date

15 October 2008

1 reference

full work available at URL

31 July 2017

https://www.karger.com/Article/Pdf/151737

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20824007

https://europepmc.org/articles/PMC2930995

8 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20824007

https://europepmc.org/articles/PMC2930995?pdf=render

8 July 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20824007

https://doi.org/10.1159/000151737

8 July 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20824007

http://www.karger.com/Article/Pdf/151737

8 July 2024

1 reference

https://api.crossref.org/works/10.1159/000151737

8 July 2024

1 reference

31 July 2017

volume

3

1 reference

31 July 2017

issue

s2

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31 July 2017

page(s)

3-10

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A PROTEOLYTIC ENZYME OF SERUM: CHARACTERIZATION, ACTIVATION, AND REACTION WITH INHIBITORS.

31 July 2017

cites work

1 reference

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5 July 2018

Epigenetics in cancer

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Systematic review: gene expression profiling assays in early-stage breast cancer

5 July 2018

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Quantitative RT-PCR assays for the determination of urokinase-type plasminogen activator and plasminogen activator inhibitor type 1 mRNA in primary tumor tissue of breast cancer patients: comparison to antigen quantification by ELISA.

5 July 2018

1 reference

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American Society of Clinical Oncology 2007 update of recommendations for the use of tumor markers in breast cancer

5 July 2018

1 reference

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Inhibition of PAI-1 expression in breast cancer carcinoma cells by siRNA at nanomolar range

5 July 2018

1 reference

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Tumor-associated proteolytic factors uPA and PAI-1: critical appraisal of their clinical relevance in breast cancer and their integration into decision-support algorithms

5 July 2018

1 reference

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From Trousseau to angiogenesis: the link between the haemostatic system and cancer.

5 July 2018

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Prognostic value of PAI1 in invasive breast cancer: evidence that tumor-specific factors are more important than genetic variation in regulating PAI1 expression

5 July 2018

1 reference

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Urokinase-receptor (u-PAR): an essential player in multiple games of cancer: a review on its role in tumor progression, invasion, metastasis, proliferation/dormancy, clinical outcome and minimal residual disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930995

Procedures for the quantitative protein determination of urokinase and its inhibitor, PAI-1, in human breast cancer tissue extracts by ELISA.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930995

Proteases and glioma angiogenesis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930995

Prognostic and predictive factors revisited

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930995

Molecular mechanisms of fibrinolysis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930995

Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930995

In vitro suppression of urokinase plasminogen activator in breast cancer cells--a comparison of two antisense strategies.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930995

A methylated oligonucleotide induced methylation of GSTP1 promoter and suppressed its expression in A549 lung adenocarcinoma cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930995

uPA and uPAR in fibrinolysis, immunity and pathology

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930995

Demethylation of urokinase promoter as a prognostic marker in patients with breast carcinoma.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930995

The fibrinolytic activity of urine.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930995

THE FIBRINOLYTIC SYSTEM IN HEALTH AND DISEASE

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930995

PATHOLOGICAL FIBRINOLYSIS.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930995

THE DEVELOPMENT OF IDEAS ON FIBRINOLYSIS

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930995

ε-AMINOCAPROIC ACID AND OTHER INHIBITORS OF FIBRINOLYSIS

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930995

uPAR: a versatile signalling orchestrator

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930995

Interference with the urokinase plasminogen activator system: a promising therapy concept for solid tumours

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930995

Randomized adjuvant chemotherapy trial in high-risk, lymph node-negative breast cancer patients identified by urokinase-type plasminogen activator and plasminogen activator inhibitor type 1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930995

Urokinase receptor: a molecular organizer in cellular communication.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930995

Transcriptional regulation of urokinase (uPA) gene expression in breast cancer cells: role of DNA methylation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930995

Tumor marker utility grading system: a framework to evaluate clinical utility of tumor markers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930995

Both the cytosols and detergent extracts of breast cancer tissues are suited to evaluate the prognostic impact of the urokinase-type plasminogen activator and its inhibitor, plasminogen activator inhibitor type 1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930995

Plasminogen activators and plasminogen activator inhibitors: biochemical aspects

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930995

Biological and clinical aspects of plasminogen activator inhibitor type 2.

5 July 2018

1 reference

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Isolation from human plasma of a plasminogen activator identical to urinary high molecular weight urokinase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930995

Plasminogen-activator-producing Tumour

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930995

A cellular binding site for the Mr 55,000 form of the human plasminogen activator, urokinase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930995

Receptors for plasminogen activator, urokinase, in normal and Rous sarcoma virus-transformed mouse fibroblasts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930995

Plasminogen activators, tissue degradation, and cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930995

Clinical relevance of the urokinase-type and tissue-type plasminogen activators and of their type 1 inhibitor in breast cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930995

Type-1 plasminogen activator inhibitor in human breast carcinomas

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930995

Release of plasminogen activator from normal and neoplastic endometrium

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930995

Purification and characterization of a plasminogen activator secreted by cultured human pancreatic carcinoma cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930995

Fibrinolysis; its mechanism and significance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930995

Taking gene-expression profiling to the clinic: when will molecular signatures become relevant to patient care?

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930995

European Organisation for Research and Treatment of Cancer (EORTC) Pathobiology Group standard operating procedure for the preparation of human tumour tissue extracts suited for the quantitative analysis of tissue-associated biomarkers.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930995

Measurement of plasminogen activator system components in plasma and tumor tissue extracts obtained from patients with breast cancer: an EORTC Receptor and Biomarker Group collaboration

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930995

Studies on a proteolytic enzyme system of the blood. Activation of profibrinolysin by serum fibrinolysokinase.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930995

Proteolytic enzymes in blood.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930995

Blood clotting and related processes

28 October 2018

1 reference

12 December 2020

A Group of Patients with Impaired Plasma Fibrinolytic System and Selective Inhibition of Tissue Activator-Induced Fibrinolysis

1 reference

12 December 2020

Multiple forms of plasminogen activator in human breast tumors

1 reference

12 December 2020

Isolation of a plasminogen activator (urokinase) from urine

1 reference

12 December 2020

Expression of plasminogen activator inhibitors type 1 and type 3 and urokinase plasminogen activator protein and mRNA in breast cancer

1 reference

12 December 2020

Urokinase-plasminogen activator, a marker for aggressive breast carcinomas. Preliminary report

1 reference

12 December 2020

Urokinase Inhibitor in Human Placenta

1 reference

12 December 2020

CpG methylation of the PAI-1 gene 5'-flanking region is inversely correlated with PAI-1 mRNA levels in human cell lines

1 reference

12 December 2020

Isolation and characterization of urokinase from human plasma

1 reference

12 December 2020

Content and characterization of plasminogen activators in human lung tumors and normal lung tissue

1 reference

12 December 2020

Plasminogen activator inhibitor-1 4G/5G polymorphism in breast cancer patients and its association with tissue PAI-1 levels and tumor severity

1 reference

12 December 2020

Purification of an inhibitor of plasminogen activator (antiactivator) synthesized by endothelial cells

1 reference

12 December 2020

Clinical impact of the plasminogen activation system in tumor invasion and metastasis: prognostic relevance and target for therapy

1 reference

12 December 2020

Urokinase-type plasminogen activator antigen and early relapse in breast cancer

1 reference

12 December 2020

Urokinase-type plasminogen activator and plasminogen activator inhibitor type-1 mRNA assessment in breast cancer by means of NASBA: correlation with protein expression

1 reference

12 December 2020

Functional plasminogen activator inhibitor-1 gene variants and breast cancer survival

1 reference

12 December 2020

Plasminogen activator content of human colon tumors and normal mucosae: separation of enzymes and partial purification

1 reference

12 December 2020

Suppression of rat breast cancer metastasis and reduction of primary tumour growth by the small synthetic urokinase inhibitor WX-UK1

1 reference

12 December 2020

Pooled analysis of prognostic impact of urokinase-type plasminogen activator and its inhibitor PAI-1 in 8377 breast cancer patients

1 reference

12 December 2020

FIBRINOLYSIS IN PATIENTS WITH PROSTATIC CANCER

1 reference

12 December 2020

Immunological identity of urokinase and ovarian carcinoma plasminogen activator released in tissue culture

1 reference

12 December 2020

Prognostic value of uPA, PAI-1 and PAI-2 mRNA expression in primary breast cancer

1 reference

12 December 2020

Shaping the future of biomarker research in breast cancer to ensure clinical relevance

1 reference

12 December 2020

Identifiers

DOI

10.1159/000151737

1 reference

31 July 2017

1 reference

31 July 2017

1 reference