(Q34102682)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22174673%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

title

A novel role for the NLRC4 inflammasome in mucosal defenses against the fungal pathogen Candida albicans (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22174673%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

1 reference

8

1 reference

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18 January 2020

author name string

Jeffrey Tomalka

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22174673%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Sandhya Ganesan

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22174673%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Elaheh Azodi

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22174673%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Krupen Patel

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22174673%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Parth Majmudar

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22174673%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Brian A Hall

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22174673%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Katherine A Fitzgerald

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22174673%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

publication date

8 December 2011

1 reference

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18 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22174673%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22174673%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22174673%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

page(s)

e1002379

1 reference

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Creative Commons Attribution 4.0 International

18 January 2020

copyright license

start time

8 December 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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5 July 2018

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5 July 2018

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The NLRP3 inflammasome: a sensor for metabolic danger?

5 July 2018

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5 July 2018

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5 July 2018

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An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

5 July 2018

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AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

5 July 2018

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AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

5 July 2018

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5 July 2018

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5 July 2018

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Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Identification and Biological Characterization of Mouse beta-defensin 14, the orthologue of human beta-defensin 3

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Intracellular type III secretion by cytoplasmic Shigella flexneri promotes caspase-1-dependent macrophage cell death

5 July 2018

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Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophages

5 July 2018

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Nonclassical IL-1 beta secretion stimulated by P2X7 receptors is dependent on inflammasome activation and correlated with exosome release in murine macrophages

5 July 2018

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5 July 2018

1 reference

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Effect of neutropenia and treatment delay on the response to antifungal agents in experimental disseminated candidiasis

5 July 2018

1 reference

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Regulation of Legionella phagosome maturation and infection through flagellin and host Ipaf.

5 July 2018

1 reference

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Intracellular pattern recognition receptors in the host response

5 July 2018

1 reference

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Role of human beta-defensins in HIV infection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234225

Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234225

Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234225

Cryopyrin activates the inflammasome in response to toxins and ATP

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234225

Gout-associated uric acid crystals activate the NALP3 inflammasome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234225

Induction of toll-like receptors and NALP/PAN/PYPAF family members by modified oligonucleotides in lung epithelial carcinoma cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234225

Human beta-defensins: differential activity against candidal species and regulation by Candida albicans

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234225

Dectin-1 mediates macrophage recognition of Candida albicans yeast but not filaments.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234225

Candidacidal effects of two antimicrobial peptides: histatin 5 causes small membrane defects, but LL-37 causes massive disruption of the cell membrane

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234225

Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234225

Nosocomial bloodstream infections in US hospitals: analysis of 24,179 cases from a prospective nationwide surveillance study

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234225

Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234225

Human beta-defensins 2 and 3 demonstrate strain-selective activity against oral microorganisms

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234225

Human epithelial beta-defensins 2 and 3 inhibit HIV-1 replication

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234225

NALPs: a novel protein family involved in inflammation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234225

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234225

Dectin-1 is a major beta-glucan receptor on macrophages

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234225

Epithelial antimicrobial peptides in host defense against infection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234225

Interleukin-18, a proinflammatory cytokine.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234225

Modulation of neutrophil function in host defense against disseminated Candida albicans infection in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234225

5 July 2018

Human beta-defensin-2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234225

Interleukin-18 and interleukin-1 beta: two cytokine substrates for ICE (caspase-1).

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234225

Production of beta-defensins by human airway epithelia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234225

Activities of LL-37, a cathelin-associated antimicrobial peptide of human neutrophils

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234225

Human beta-defensin-1: an antimicrobial peptide of urogenital tissues

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234225

Mouse beta-defensin 1 is a salt-sensitive antimicrobial peptide present in epithelia of the lung and urogenital tract

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234225

Proinflammatory and anti-inflammatory cytokines as mediators in the pathogenesis of septic shock

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234225

Human airway epithelia express a beta-defensin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234225

Human beta-defensin-1 is a salt-sensitive antibiotic in lung that is inactivated in cystic fibrosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234225

Biologic basis for interleukin-1 in disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234225

Cystic fibrosis airway epithelia fail to kill bacteria because of abnormal airway surface fluid.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234225

A genetic locus of enterocyte effacement conserved among diverse enterobacterial pathogens

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234225

The biology of interleukin-1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234225

Candidemia in a tertiary care hospital: epidemiology, risk factors, and predictors of mortality

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234225

Immune recognition of Candida albicans beta-glucan by dectin-1.

5 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002379

Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002379

Mice lacking both G-CSF and IL-6 are more susceptible to Candida albicans infection: critical role of neutrophils in defense against Candida albicans

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002379

Requirement of interleukin-17A for systemic anti-Candida albicans host defense in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002379

The macrophage mannose receptor induces IL-17 in response to Candida albicans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002379

Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002379

A novel P2X7 receptor activator, the human cathelicidin-derived peptide LL37, induces IL-1 beta processing and release

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002379

Granzyme B is a novel interleukin-18 converting enzyme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002379

Assembly and function of a cytosolic form of NADH-specific isocitrate dehydrogenase in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002379

A single-nucleotide polymorphism in the human beta-defensin 1 gene is associated with HIV-1 infection in Italian children

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002379

DEFB1 gene polymorphisms and increased risk of HIV-1 infection in Brazilian children.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002379

DEFB-1 genetic polymorphism screening in HIV-1 positive pregnant women and their children.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002379

A novel mouse beta defensin, Defb2, which is upregulated in the airways by lipopolysaccharide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002379

The human cathelicidin peptide LL-37 and truncated variants induce segregation of lipids and proteins in the plasma membrane of Candida albicans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002379

Antimicrobial activities of heparin-binding peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002379

Anti-fungal activity of cathelicidins and their potential role in Candida albicans skin infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002379

Increased serum leucine, leucine-37 levels in psoriasis: positive and negative feedback loops of leucine, leucine-37 and pro- or anti-inflammatory cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002379

An antimicrobial cathelicidin peptide, human CAP18/LL-37, suppresses neutrophil apoptosis via the activation of formyl-peptide receptor-like 1 and P2X7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002379

Correlation of HDEFB1 polymorphism and susceptibility to chronic obstructive pulmonary disease in Chinese Han population.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234225

Role of protein tyrosine phosphorylation in acetaldehyde-induced disruption of epithelial tight junctions

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234225

Involvement of the NLRP3 Inflammasome in Innate and Humoral Adaptive Immune Responses to Fungal -Glucan

28 October 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002379

Association of beta-defensin 1 single nucleotide polymorphisms with Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002379

IL-23 and the Th17 pathway promote inflammation and impair antifungal immune resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002379

Human mast cell chymase cleaves pro-IL-18 and generates a novel and biologically active IL-18 fragment

21 January 2018

1 reference

12 December 2020

Granulocyte colony-stimulating factor potentiates anti-Candida albicans growth inhibitory activity of polymorphonuclear cells

1 reference

12 December 2020

Positive effect of overexpressed protein-tyrosine phosphatase PTP1C on mitogen-activated signaling in 293 cells

1 reference

12 December 2020

Phenotypic and functional characterization of mice that lack the type I receptor for IL-1

1 reference

12 December 2020

10.1371/JOURNAL.PPAT.1002379

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22174673%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22174673%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

PubMed publication ID

22174673

1 reference