(Q34103346)

31 July 2017

title

An off-target nucleostemin RNAi inhibits growth in human glioblastoma-derived cancer stem cells (English)

1 reference

31 July 2017

main subject

neoplastic stem cells

1 reference

Jon Gil-Ranedo

1

1 reference

31 July 2017

Marina Mendiburu-Eliçabe

2

1 reference

31 July 2017

Mercedes García-Villanueva

3

1 reference

31 July 2017

Diego Medina

4

1 reference

31 July 2017

Marta del Álamo

5

1 reference

31 July 2017

Marta Izquierdo

6

1 reference

31 July 2017

language of work or name

English

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publication date

12 December 2011

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31 July 2017

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31 July 2017

volume

6

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31 July 2017

issue

12

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31 July 2017

page(s)

e28753

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Creative Commons Attribution 4.0 International

31 July 2017

copyright license

start time

12 December 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3236221/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Off-target effects dominate a large-scale RNAi screen for modulators of the TGF-β pathway and reveal microRNA regulation of TGFBR2

5 July 2018

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Tumor-initiating function of nucleostemin-enriched mammary tumor cells.

5 July 2018

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Differential expression of nucleostemin, a stem cell marker, and its variants in different types of brain tumors

5 July 2018

1 reference

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T cells enhance stem-like properties and conditional malignancy in gliomas

5 July 2018

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Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application

5 July 2018

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Brain tumor treatment increases the number of cancer stem-like cells

5 July 2018

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5 July 2018

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Differential effects of Nucleostemin suppression on cell cycle arrest and apoptosis in the bladder cancer cell lines 5637 and SW1710.

5 July 2018

1 reference

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Novel role of nucleostemin in the maintenance of nucleolar architecture and integrity of small nucleolar ribonucleoproteins and the telomerase complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236221

Human glioblastoma-derived cancer stem cells: establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectors

5 July 2018

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Characterization of human embryonic stem cells with features of neoplastic progression.

5 July 2018

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Critical role of nucleostemin in pre-rRNA processing

5 July 2018

1 reference

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Exploring the role of cancer stem cells in radioresistance

5 July 2018

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Aberrant expression of nucleostemin activates p53 and induces cell cycle arrest via inhibition of MDM2

5 July 2018

1 reference

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Expression of nucleostemin in prostate cancer and its effect on the proliferation of PC-3 cells

5 July 2018

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Identification and expansion of the tumorigenic lung cancer stem cell population

5 July 2018

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Depletion of the nucleolar protein nucleostemin causes G1 cell cycle arrest via the p53 pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236221

Identification of pancreatic cancer stem cells

5 July 2018

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Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma

5 July 2018

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Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells.

5 July 2018

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Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma

5 July 2018

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A human colon cancer cell capable of initiating tumour growth in immunodeficient mice

5 July 2018

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Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236221

Nucleostemin delays cellular senescence and negatively regulates TRF1 protein stability

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236221

Evolutionarily conserved role of nucleostemin: controlling proliferation of stem/progenitor cells during early vertebrate development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236221

Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells

5 July 2018

1 reference

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Ovarian cancer side population defines cells with stem cell-like characteristics and Mullerian Inhibiting Substance responsiveness

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236221

Asymmetric and symmetric stem-cell divisions in development and cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236221

Widespread siRNA "off-target" transcript silencing mediated by seed region sequence complementarity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236221

Prospective identification of tumorigenic prostate cancer stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236221

Nucleostemin is a marker of proliferating stromal stem cells in adult human bone marrow

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236221

A tumorigenic subpopulation with stem cell properties in melanomas

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236221

siRNA-mediated off-target gene silencing triggered by a 7 nt complementation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236221

dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236221

Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236221

The effect of knocking-down nucleostemin gene expression on the in vitro proliferation and in vivo tumorigenesis of HeLa cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236221

Cancerous stem cells can arise from pediatric brain tumors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236221

Identification of a cancer stem cell in human brain tumors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236221

Prospective identification of tumorigenic breast cancer cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236221

A nucleolar mechanism controlling cell proliferation in stem cells and cancer cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236221

Malignant glioma: genetics and biology of a grave matter.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236221

Neurogenesis in the adult brain: death of a dogma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236221

A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3236221

Direct orthotopic transplantation of fresh surgical specimen preserves CD133+ tumor cells in clinically relevant mouse models of medulloblastoma and glioma.

5 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0028753

Knocking-down the expression of nucleostemin significantly decreases rate of proliferation of rat bone marrow stromal stem cells in an apparently p53-independent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0028753

Differential requirement for nucleostemin in embryonic stem cell and neural stem cell viability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0028753

Minimizing the risk of reporting false positives in large-scale RNAi screens

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0028753

10.1371/JOURNAL.PONE.0028753

21 January 2018

Identifiers

DOI

1 reference

31 July 2017

0 references

1 reference

31 July 2017

1 reference