(Q34103645)

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The human cancer antigen mesothelin is more efficiently presented to the mouse immune system when targeted to the DEC-205/CD205 receptor on dendritic cells

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Europe PubMed Central

PubMed publication ID

31 July 2017

The human cancer antigen mesothelin is more efficiently presented to the mouse immune system when targeted to the DEC-205/CD205 receptor on dendritic cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

1 reference

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Ralph M Steinman

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Europe PubMed Central

PubMed publication ID

31 July 2017

Janelle M Y Kuroiwa

2

object named as

Janelle M Y Kuroiwa

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Europe PubMed Central

PubMed publication ID

31 July 2017

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Bei Wang

1

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Europe PubMed Central

PubMed publication ID

31 July 2017

Li-Zhen He

3

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Europe PubMed Central

PubMed publication ID

31 July 2017

Anna Charalambous

4

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Europe PubMed Central

PubMed publication ID

31 July 2017

Tibor Keler

5

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Europe PubMed Central

PubMed publication ID

31 July 2017

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publication date

1 September 2009

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Europe PubMed Central

PubMed publication ID

31 July 2017

Annals of the New York Academy of Sciences

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Europe PubMed Central

PubMed publication ID

31 July 2017

1174

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Europe PubMed Central

PubMed publication ID

31 July 2017

6-17

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Europe PubMed Central

PubMed publication ID

31 July 2017

Effective depletion of regulatory T cells allows the recruitment of mesothelin-specific CD8 T cells to the antitumor immune response against a mesothelin-expressing mouse pancreatic adenocarcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933265

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Mesothelin-induced pancreatic cancer cell proliferation involves alteration of cyclin E via activation of signal transducer and activator of transcription protein 3

1 reference

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Treatment of metastatic melanoma with autologous CD4+ T cells against NY-ESO-1

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Targeting the nuclear antigen 1 of Epstein-Barr virus to the human endocytic receptor DEC-205 stimulates protective T-cell responses.

1 reference

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A systematic assessment of MHC class II peptide binding predictions and evaluation of a consensus approach

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Allogeneic granulocyte macrophage colony-stimulating factor-secreting tumor immunotherapy alone or in sequence with cyclophosphamide for metastatic pancreatic cancer: a pilot study of safety, feasibility, and immune activation

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The microbial mimic poly IC induces durable and protective CD4+ T cell immunity together with a dendritic cell targeted vaccine

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Mesothelin targeted cancer immunotherapy

1 reference

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Dendritic-cell immunotherapy: from ex vivo loading to in vivo targeting

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Mesothelin, a possible target for immunotherapy, is expressed in primary AML cells

1 reference

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Control of human mesothelin-expressing tumors by DNA vaccines

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Overexpression of folate binding protein and mesothelin are associated with uterine serous carcinoma

1 reference

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Control of mesothelin-expressing ovarian cancer using adoptive transfer of mesothelin peptide-specific CD8+ T cells

1 reference

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Mesothelin expression in human lung cancer

1 reference

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CD4 cells can be more efficient at tumor rejection than CD8 cells

1 reference

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DEC-205 receptor on dendritic cells mediates presentation of HIV gag protein to CD8+ T cells in a spectrum of human MHC I haplotypes

1 reference

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Mesothelin-MUC16 binding is a high affinity, N-glycan dependent interaction that facilitates peritoneal metastasis of ovarian tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933265

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A DNA vaccine encoding a single-chain trimer of HLA-A2 linked to human mesothelin peptide generates anti-tumor effects against human mesothelin-expressing tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933265

5 July 2018

MHC class II proteins and disease: a structural perspective

1 reference

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5 July 2018

Intensified and protective CD4+ T cell immunity in mice with anti-dendritic cell HIV gag fusion antibody vaccine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933265

5 July 2018

Identification of novel human CTL epitopes and their agonist epitopes of mesothelin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933265

5 July 2018

Targeting of antigens to activated dendritic cells in vivo cures metastatic melanoma in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933265

5 July 2018

Mesothelin-specific CD8(+) T cell responses provide evidence of in vivo cross-priming by antigen-presenting cells in vaccinated pancreatic cancer patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933265

5 July 2018

Helping the CD8(+) T-cell response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933265

5 July 2018

Mesothelin: a new target for immunotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933265

5 July 2018

In vivo targeting of antigens to maturing dendritic cells via the DEC-205 receptor improves T cell vaccination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933265

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Coordinated tumor immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933265

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Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933265

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Immune tolerance after delivery of dying cells to dendritic cells in situ

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933265

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Mesothelin is overexpressed in the vast majority of ductal adenocarcinomas of the pancreas: identification of a new pancreatic cancer marker by serial analysis of gene expression (SAGE).

1 reference

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Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo

1 reference

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Mesothelin is not required for normal mouse development or reproduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933265

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CD4(+) T cells eliminate MHC class II-negative cancer cells in vivo by indirect effects of IFN-gamma

1 reference

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Molecular cloning of mesothelin, a differentiation antigen present on mesothelium, mesotheliomas, and ovarian cancers

1 reference

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The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing

1 reference

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Characterization of the antigen (CAK1) recognized by monoclonal antibody K1 present on ovarian cancers and normal mesothelium

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DEC-205/CD205+ dendritic cells are abundant in the white pulp of the human spleen, including the border region between the red and white pulp

1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/19769731

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1749-6632.2009.04933.X

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

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