(Q34103656)

31 July 2017

1 reference

title

ROCK inhibition as a therapy for spinal muscular atrophy: understanding the repercussions on multiple cellular targets (English)

1 reference

25221469

31 July 2017

main subject

spinal muscular atrophy

1 reference

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25221469%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Melissa Bowerman

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25221469%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

author name string

Emmanuelle Coque

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25221469%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

publication date

28 August 2014

1 reference

25221469

Frontiers in Neuroscience

31 July 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25221469%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25221469%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

page(s)

271

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25221469%20AND%20SRC:MED&resulttype=core&format=json

Survival motor neuron protein deficiency impairs myotube formation by altering myogenic gene expression and focal adhesion dynamics

2 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Defects in pancreatic development and glucose metabolism in SMN-depleted mice independent of canonical spinal muscular atrophy neuromuscular pathology.

28 July 2018

1 reference

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More than a bystander: the contributions of intrinsic skeletal muscle defects in motor neuron diseases.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

The intriguing case of motor neuron disease: ALS and SMA come closer.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Kamolonol suppresses angiotensin II-induced stress fiber formation and cellular hypertrophy through inhibition of Rho-associated kinase 2 activity.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Biochemical and physiological regulation of cardiac myocyte contraction by cardiac-specific myosin light chain kinase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Spinal muscular atrophy astrocytes exhibit abnormal calcium regulation and reduced growth factor production

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

A novel strategy to increase the proliferative potential of adult human β-cells while maintaining their differentiated phenotype.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Rho-associated coiled-coil kinase (ROCK) signaling and disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Spinal muscular atrophy: going beyond the motor neuron

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Signaling mechanisms and functional roles of cofilin phosphorylation and dephosphorylation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

An SMN-dependent U12 splicing event essential for motor circuit function

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Glucose metabolism and pancreatic defects in spinal muscular atrophy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Mutations in the profilin 1 gene cause familial amyotrophic lateral sclerosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Mouse models of SMA: tools for disease characterization and therapeutic development

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Inhibition of Rho-kinase ameliorates myocardial remodeling and fibrosis in pressure overload and myocardial infarction: role of TGF-β1-TAK1.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Fasudil improves survival and promotes skeletal muscle development in a mouse model of spinal muscular atrophy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Partial restoration of cardio-vascular defects in a rescued severe model of spinal muscular atrophy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

A critical smn threshold in mice dictates onset of an intermediate spinal muscular atrophy phenotype associated with a distinct neuromuscular junction pathology.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Severe neuromuscular denervation of clinically relevant muscles in a mouse model of spinal muscular atrophy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Agrin triggers the clustering of raft-associated acetylcholine receptors through actin cytoskeleton reorganization

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

CREB and the CRTC co-activators: sensors for hormonal and metabolic signals

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Increased IGF-1 in muscle modulates the phenotype of severe SMA mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

The Rho kinase inhibitor Fasudil up-regulates astrocytic glutamate transport subsequent to actin remodelling in murine cultured astrocytes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Mouse survival motor neuron alleles that mimic SMN2 splicing and are inducible rescue embryonic lethality early in development but not late

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

S100B protein stimulates microglia migration via RAGE-dependent up-regulation of chemokine expression and release

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Synaptic defects in the spinal and neuromuscular circuitry in a mouse model of spinal muscular atrophy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Cardiac defects contribute to the pathology of spinal muscular atrophy models

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Arrhythmia and cardiac defects are a feature of spinal muscular atrophy model mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Early heart failure in the SMNDelta7 model of spinal muscular atrophy and correction by postnatal scAAV9-SMN delivery

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Alternative splicing events are a late feature of pathology in a mouse model of spinal muscular atrophy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Non-cell autonomous toxicity in neurodegenerative disorders: ALS and beyond

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Oligodendrocytes: biology and pathology

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Inflammation in ALS and SMA: sorting out the good from the evil

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Spinal muscular atrophy: why do low levels of survival motor neuron protein make motor neurons sick?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Rho kinase-1 mediates cardiac fibrosis by regulating fibroblast precursor cell differentiation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Neuroscience: Glia — more than just brain glue

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

S100B's double life: intracellular regulator and extracellular signal.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Role of the Rho-ROCK (Rho-associated kinase) signaling pathway in the regulation of pancreatic beta-cell function

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Physiology of the pancreatic alpha-cell and glucagon secretion: role in glucose homeostasis and diabetes.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Congenital heart disease is a feature of severe infantile spinal muscular atrophy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Plastin 3 is a protective modifier of autosomal recessive spinal muscular atrophy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Pathways involved in the transition from hypertension to hypertrophy to heart failure. Treatment strategies

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Medical considerations of long-term survival of Werdnig-Hoffmann disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

The GLUT4 glucose transporter

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Regulation and dysregulation of glutamate transporters.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Selective deletion of Pten in pancreatic beta cells leads to increased islet mass and resistance to STZ-induced diabetes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

The Rho family of small GTPases: crucial regulators of skeletal myogenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Insulin-like growth factor-I treatment of growth disorders, diabetes mellitus and insulin resistance

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Acute vasodilator effects of a Rho-kinase inhibitor, fasudil, in patients with severe pulmonary hypertension

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Modulation of acto-myosin contractility in skeletal muscle myoblasts uncouples growth arrest from differentiation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Neurotrophins regulate Schwann cell migration by activating divergent signaling pathways dependent on Rho GTPases

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Smn, the spinal muscular atrophy-determining gene product, modulates axon growth and localization of beta-actin mRNA in growth cones of motoneurons

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

RhoA/ROCK regulation of neuritogenesis via profilin IIa-mediated control of actin stability

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Intact satellite cells lead to remarkable protection against Smn gene defect in differentiated skeletal muscle.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

New insights into neuron-glia communication

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

The ADF/cofilin family: actin-remodeling proteins

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Deletion of murine SMN exon 7 directed to skeletal muscle leads to severe muscular dystrophy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Profilin II is alternatively spliced, resulting in profilin isoforms that are differentially expressed and have distinct biochemical properties

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

The human centromeric survival motor neuron gene (SMN2) rescues embryonic lethality in Smn(-/-) mice and results in a mouse with spinal muscular atrophy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

A mouse model for spinal muscular atrophy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Cofilin phosphorylation and actin cytoskeletal dynamics regulated by rho- and Cdc42-activated LIM-kinase 2

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

The spinal muscular atrophy disease gene product, SMN: A link between snRNP biogenesis and the Cajal (coiled) body

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

A single nucleotide in the SMN gene regulates splicing and is responsible for spinal muscular atrophy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Development of the vertebrate neuromuscular junction

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Abnormal fatty acid metabolism in childhood spinal muscular atrophy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

The Rho family G proteins play a critical role in muscle differentiation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Rho GTPases and the actin cytoskeleton

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Inactivation of the survival motor neuron gene, a candidate gene for human spinal muscular atrophy, leads to massive cell death in early mouse embryos

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Correlation between severity and SMN protein level in spinal muscular atrophy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

The neurobiology of childhood spinal muscular atrophy.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Hypoglycemic effect of insulin-like growth factor-1 in mice lacking insulin receptors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Rho family GTP-binding proteins in growth cone signalling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase)

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

A novel nuclear structure containing the survival of motor neurons protein

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Muscle deficiency and neonatal death in mice with a targeted mutation in the myogenin gene

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Characterization of a novel cofilin isoform that is predominantly expressed in mammalian skeletal muscle

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Identification and characterization of a spinal muscular atrophy-determining gene

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Fatty acid oxidation abnormalities in childhood-onset spinal muscular atrophy: primary or secondary defect(s)?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Spinal muscular atrophy type I combined with atrial septal defect in three sibs.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Incidence, prevalence, and gene frequency studies of chronic childhood spinal muscular atrophy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Lipid disturbances associated with spiral muscular atrophy. Clinical, electromyographic, histochemical, and lipid studies

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Astrocyte stellation induced by Rho kinase inhibitors in culture

28 July 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

Plastin 3 ameliorates spinal muscular atrophy via delayed axon pruning and improves neuromuscular junction functionality.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

Lim kinase regulates the development of olfactory and neuromuscular synapses

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

Neuropathological analysis in spinal muscular atrophy type II.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

Reduced expression of nicotinic AChRs in myotubes from spinal muscular atrophy I patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

Trichostatin A increases SMN expression and survival in a mouse model of spinal muscular atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

Inhibition of Rho-kinase protects the heart against ischemia/reperfusion injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

SMN, profilin IIa and plastin 3: a link between the deregulation of actin dynamics and SMA pathogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

Rho-kinase inactivation prolongs survival of an intermediate SMA mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

Myogenic program dysregulation is contributory to disease pathogenesis in spinal muscular atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

SMN deficiency attenuates migration of U87MG astroglioma cells through the activation of RhoA.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

Disruption of an SF2/ASF-dependent exonic splicing enhancer in SMN2 causes spinal muscular atrophy in the absence of SMN1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

The role of the cytoskeleton in neuromuscular junction formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

Sphingosine 1-phosphate induces cell contraction via calcium-independent/Rho-dependent pathways in undifferentiated skeletal muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

Rho kinase inhibitors Y27632 and H1152 augment neurite extension in the presence of cultured Schwann cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

Long-term inhibition of Rho-kinase ameliorates diastolic heart failure in hypertensive rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

Role of Rho-kinase in regulation of insulin action and glucose homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

Increased rho-kinase activity in hypertensive patients with left ventricular hypertrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

Neonatal spinal muscular atrophy with multiple contractures, bone fractures, respiratory insufficiency and 5q13 deletion.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

Glial bundles in spinal nerve roots: a form of isomorphic gliosis at the junction of the central and peripheral nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

The role of the Rho GTPases in neuronal development

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

Long-term inhibition of Rho-kinase suppresses left ventricular remodeling after myocardial infarction in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

Oxidative stress and disturbed glutamate transport in spinal muscular atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

Bilateral crosstalk of rho- and extracellular-signal-regulated-kinase (ERK) pathways is confined to an unidirectional mode in spinal muscular atrophy (SMA).

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

SMN-dependent intrinsic defects in Schwann cells in mouse models of spinal muscular atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

Loss of myogenin in postnatal life leads to normal skeletal muscle but reduced body size.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

Diabetic Ketoacidosis in an Adult Patient With Spinal Muscular Atrophy Type II: Further Evidence of Extraneural Pathology Due to Survival Motor Neuron 1 Mutation?

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

Acute inhibition of Rho-kinase improves cardiac contractile function in streptozotocin-diabetic rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

In vivo dilatation of the ductus arteriosus by Rho kinase inhibition in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

Growth cone guidance: first steps towards a deeper understanding

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

Defects in neuromuscular junction remodelling in the Smn(2B/-) mouse model of spinal muscular atrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

Selective vulnerability of motor neurons and dissociation of pre- and post-synaptic pathology at the neuromuscular junction in mouse models of spinal muscular atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

Marked increase of insulin gene transcription by suppression of the Rho/Rho-kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

PTEN depletion rescues axonal growth defect and improves survival in SMN-deficient motor neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

The spinal muscular atrophy disease protein SMN is linked to the Rho-kinase pathway via profilin.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

Regulation of astrocyte morphology by RhoA and lysophosphatidic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

Effects of the compact mutant myostatin allele Mstn (Cmpt-dl1Abc) introgressed into a high growth mouse line on skeletal muscle cellularity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

Pharmacological profile of hydroxy fasudil as a selective rho kinase inhibitor on ischemic brain damage

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

A role for complexes of survival of motor neurons (SMN) protein with gemins and profilin in neurite-like cytoplasmic extensions of cultured nerve cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

Hypertension, angiotensin II, and oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

Trichostatin A improves insulin stimulated glucose utilization and insulin signaling transduction through the repression of HDAC2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

Rho kinase as a therapeutic target in cardiovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

Mechanisms involved in spinal cord central synapse loss in a mouse model of spinal muscular atrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

SMN deficiency causes tissue-specific perturbations in the repertoire of snRNAs and widespread defects in splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2014.00271

Rho signaling pathway targeted to promote spinal cord repair.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Alternative splicing of the mouse profilin II gene generates functionally different profilin isoforms

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Cloning, characterization, and copy number of the murine survival motor neuron gene: homolog of the spinal muscular atrophy-determining gene

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148024

Repulsive migration of Schwann cells induced by Slit-2 through Ca2+-dependent RhoA-myosin signaling

28 October 2018

1 reference

12 December 2020

International SMA consortium meeting. (26-28 June 1992, Bonn, Germany)

1 reference

12 December 2020

Familial adult-onset proximal spinal muscular atrophy. Report of a family with type II hyperlipoproteinemia

1 reference

12 December 2020

SMNDelta7, the major product of the centromeric survival motor neuron (SMN2) gene, extends survival in mice with spinal muscular atrophy and associates with full-length SMN

1 reference

12 December 2020

Angiotensin II activates RhoA in cardiac myocytes: a critical role of RhoA in angiotensin II-induced premyofibril formation

1 reference

12 December 2020

Smn depletion alters profilin II expression and leads to upregulation of the RhoA/ROCK pathway and defects in neuronal integrity

1 reference

12 December 2020

A negative element in SMN2 exon 7 inhibits splicing in spinal muscular atrophy

1 reference

12 December 2020

Classification of spinal muscular atrophies

1 reference

12 December 2020

Congenital heart defects in spinal muscular atrophy type I: a clinical report of two siblings and a review of the literature

1 reference

12 December 2020

SMN gene deletion in variant of infantile spinal muscular atrophy

1 reference

12 December 2020

Hypomorphic Smn knockdown C2C12 myoblasts reveal intrinsic defects in myoblast fusion and myotube morphology

1 reference

12 December 2020

Lesional RhoA+ cell numbers are suppressed by anti-inflammatory, cyclooxygenase-inhibiting treatment following subacute spinal cord injury

1 reference

12 December 2020

An autopsy case of spinal muscular atrophy type III (Kugelberg-Welander disease)

1 reference

12 December 2020

A role for polyproline motifs in the spinal muscular atrophy protein SMN. Profilins bind to and colocalize with smn in nuclear gems

1 reference

12 December 2020

Identifiers

DOI

10.3389/FNINS.2014.00271

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25221469%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25221469%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

25221469

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25221469%20AND%20SRC:MED&resulttype=core&format=json