(Q34107392)

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A mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (MEK)-dependent transcriptional program controls activation of the early growth response 1 (EGR1) gene during amino acid limitation

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scholarly article

1 reference

Europe PubMed Central

31 July 2017

A mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (MEK)-dependent transcriptional program controls activation of the early growth response 1 (EGR1) gene during amino acid limitation (English)

1 reference

Europe PubMed Central

31 July 2017

object named as

Henry V Baker

7

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author name string

Jixiu Shan

1

1 reference

Europe PubMed Central

31 July 2017

Mukundh N Balasubramanian

2

1 reference

Europe PubMed Central

31 July 2017

William Donelan

3

1 reference

Europe PubMed Central

31 July 2017

Lingchen Fu

4

1 reference

Europe PubMed Central

31 July 2017

Jaclyn Hayner

5

1 reference

Europe PubMed Central

31 July 2017

Maria-Cecilia Lopez

6

1 reference

Europe PubMed Central

31 July 2017

Michael S Kilberg

8

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Europe PubMed Central

31 July 2017

language of work or name

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publication date

15 July 2014

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Europe PubMed Central

31 July 2017

Journal of Biological Chemistry

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Europe PubMed Central

31 July 2017

289

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Europe PubMed Central

31 July 2017

35

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Europe PubMed Central

31 July 2017

24665-24679

1 reference

Europe PubMed Central

31 July 2017

The stress-regulated transcription factor CHOP promotes hepatic inflammatory gene expression, fibrosis, and oncogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148889

5 July 2018

Elevated cJUN expression and an ATF/CRE site within the ATF3 promoter contribute to activation of ATF3 transcription by the amino acid response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148889

5 July 2018

MAP kinase signalling cascades and transcriptional regulation

1 reference

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5 July 2018

ATF4-dependent regulation of the JMJD3 gene during amino acid deprivation can be rescued in Atf4-deficient cells by inhibition of deacetylation.

1 reference

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5 July 2018

Heparin inhibits Hepatocyte Growth Factor induced motility and invasion of hepatocellular carcinoma cells through early growth response protein 1.

1 reference

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5 July 2018

ELK1 uses different DNA binding modes to regulate functionally distinct classes of target genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148889

5 July 2018

The transcription factor network associated with the amino acid response in mammalian cells

1 reference

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Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapy

1 reference

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Surgical stress resistance induced by single amino acid deprivation requires Gcn2 in mice

1 reference

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Immediate-early gene activation by the MAPK pathways: what do and don't we know?

1 reference

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5 July 2018

Early growth response 1--a transcription factor in the crossfire of signal transduction cascades

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148889

5 July 2018

Auto-activation of c-JUN gene by amino acid deprivation of hepatocellular carcinoma cells reveals a novel c-JUN-mediated signaling pathway

1 reference

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Genomic and biochemical insights into the specificity of ETS transcription factors

1 reference

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5 July 2018

The eIF2 kinase GCN2 is essential for the murine immune system to adapt to amino acid deprivation by asparaginase

1 reference

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5 July 2018

The GCN2-ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation.

1 reference

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5 July 2018

Expression profiling after activation of amino acid deprivation response in HepG2 human hepatoma cells

1 reference

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5 July 2018

Molecular mechanisms involved in the adaptation to amino acid limitation in mammals

1 reference

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The role of NF-kappaB in Hepatitis b virus X protein-mediated upregulation of VEGF and MMPs

1 reference

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5 July 2018

Identification of a novel amino acid response pathway triggering ATF2 phosphorylation in mammals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148889

5 July 2018

ATF4-dependent transcription mediates signaling of amino acid limitation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148889

5 July 2018

GCN2 protein kinase is required to activate amino acid deprivation responses in mice treated with the anti-cancer agent L-asparaginase.

1 reference

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Hepatocyte growth factor induced up-regulations of VEGF through Egr-1 in hepatocellular carcinoma cells

1 reference

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5 July 2018

Elevated ATF4 expression, in the absence of other signals, is sufficient for transcriptional induction via CCAAT enhancer-binding protein-activating transcription factor response elements

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148889

5 July 2018

Amino acid limitation regulates the expression of genes involved in several specific biological processes through GCN2-dependent and GCN2-independent pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148889

5 July 2018

C/EBP homology protein (CHOP) interacts with activating transcription factor 4 (ATF4) and negatively regulates the stress-dependent induction of the asparagine synthetase gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148889

5 July 2018

Despite increased ATF4 binding at the C/EBP-ATF composite site following activation of the unfolded protein response, system A transporter 2 (SNAT2) transcription activity is repressed in HepG2 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148889

5 July 2018

MEK signaling is required for phosphorylation of eIF2alpha following amino acid limitation of HepG2 human hepatoma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148889

5 July 2018

HepG2/C3A cells respond to cysteine deprivation by induction of the amino acid deprivation/integrated stress response pathway.

1 reference

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5 July 2018

Deprivation of protein or amino acid induces C/EBPbeta synthesis and binding to amino acid response elements, but its action is not an absolute requirement for enhanced transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148889

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TRB3 protects cells against the growth inhibitory and cytotoxic effect of ATF4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148889

5 July 2018

Activation of the ATF3 gene through a co-ordinated amino acid-sensing response programme that controls transcriptional regulation of responsive genes following amino acid limitation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148889

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Egr-1 is activated by 17beta-estradiol in MCF-7 cells by mitogen-activated protein kinase-dependent phosphorylation of ELK-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148889

5 July 2018

Amino acid deprivation induces the transcription rate of the human asparagine synthetase gene through a timed program of expression and promoter binding of nutrient-responsive basic region/leucine zipper transcription factors as well as localized hi

1 reference

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Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells

1 reference

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Delayed hepatocellular mitotic progression and impaired liver regeneration in early growth response-1-deficient mice.

1 reference

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The GCN2 eIF2alpha kinase is required for adaptation to amino acid deprivation in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148889

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Response of VEGF expression to amino acid deprivation and inducers of endoplasmic reticulum stress.

1 reference

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5 July 2018

ATF4 is a mediator of the nutrient-sensing response pathway that activates the human asparagine synthetase gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148889

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Regulated translation initiation controls stress-induced gene expression in mammalian cells

1 reference

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Perk is essential for translational regulation and cell survival during the unfolded protein response

1 reference

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Complexes containing activating transcription factor (ATF)/cAMP-responsive-element-binding protein (CREB) interact with the CCAAT/enhancer-binding protein (C/EBP)-ATF composite site to regulate Gadd153 expression during the stress response

1 reference

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Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

1 reference

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Growth hormone stimulates phosphorylation and activation of elk-1 and expression of c-fos, egr-1, and junB through activation of extracellular signal-regulated kinases 1 and 2.

1 reference

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gadd153/Chop10, a potential target gene of the transcriptional repressor ATF3.

1 reference

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Transformation of mammalian cells by constitutively active MAP kinase kinase

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Identification and characterization of the Egr-1 gene product, a DNA-binding zinc finger protein induced by differentiation and growth signals

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A feedback transcriptional mechanism controls the level of the arginine/lysine transporter cat-1 during amino acid starvation

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Impersonalized medicine.

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Acute lymphoblastic leukemia

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12 December 2020

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Identifiers

10.1074/JBC.M114.565028

1 reference

Europe PubMed Central

31 July 2017

1 reference

Europe PubMed Central

31 July 2017

1 reference

Europe PubMed Central

31 July 2017

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