(Q34109260)

31 July 2017

title

Possible involvement of lysosomal dysfunction in pathological changes of the brain in aged progranulin-deficient mice (English)

1 reference

31 July 2017

Yoshinori Tanaka

1

1 reference

31 July 2017

James K Chambers

2

1 reference

31 July 2017

Takashi Matsuwaki

3

1 reference

31 July 2017

Keitaro Yamanouchi

4

1 reference

31 July 2017

Masugi Nishihara

5

1 reference

31 July 2017

publication date

15 July 2014

1 reference

Acta Neuropathologica Communications

31 July 2017

published in

1 reference

31 July 2017

volume

2

1 reference

31 July 2017

page(s)

78

1 reference

describes a project that uses

31 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4149276/fullTextXML

inferred from PubMed Central ID database lookup

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28 July 2018

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Exacerbated inflammatory responses related to activated microglia after traumatic brain injury in progranulin-deficient mice

28 July 2018

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28 July 2018

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28 July 2018

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Strikingly different clinicopathological phenotypes determined by progranulin-mutation dosage

28 July 2018

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Galactolipid deficiency in the early pathogenesis of neuronal ceroid lipofuscinosis model Cln8mnd : implications to delayed myelination and oligodendrocyte maturation.

28 July 2018

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28 July 2018

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Behavioral deficits and progressive neuropathology in progranulin-deficient mice: a mouse model of frontotemporal dementia

28 July 2018

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Accelerated lipofuscinosis and ubiquitination in granulin knockout mice suggest a role for progranulin in successful aging

28 July 2018

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28 July 2018

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Mutant superoxide dismutase 1 overexpression in NSC-34 cells: effect of trehalose on aggregation, TDP-43 localization and levels of co-expressed glycoproteins

28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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Rapamycin rescues TDP-43 mislocalization and the associated low molecular mass neurofilament instability

28 July 2018

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28 July 2018

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Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease

28 July 2018

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TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

28 July 2018

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Successive neuron loss in the thalamus and cortex in a mouse model of infantile neuronal ceroid lipofuscinosis

28 July 2018

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Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21

28 July 2018

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28 July 2018

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28 July 2018

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Species-specific ultrastructure of neuronal lipofuscin in hippocampus and neocortex of subhuman mammals and humans

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149276

Increased lysosomal biogenesis in activated microglia and exacerbated neuronal damage after traumatic brain injury in progranulin-deficient mice.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149276

The frontotemporal lobar degeneration risk factor, TMEM106B, regulates lysosomal morphology and function

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149276

Exacerbated neuronal ceroid lipofuscinosis phenotype in Cln1/5 double-knockout mice

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149276

Cellular ageing, increased mortality and FTLD-TDP-associated neuropathology in progranulin knockout mice

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149276

Selective spatiotemporal patterns of glial activation and neuron loss in the sensory thalamocortical pathways of neuronal ceroid lipofuscinosis 8 mice

28 October 2018

1 reference

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Iron efflux from astrocytes plays a role in remyelination.

28 October 2018

1 reference

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PGRN is a key adipokine mediating high fat diet-induced insulin resistance and obesity through IL-6 in adipose tissue

28 October 2018

1 reference

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Sudan Black B treatment reduces autofluorescence and improves resolution of in situ hybridization specific fluorescent signals of brain sections

28 October 2018

1 reference

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28 October 2018

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Neuronal ceroid lipofuscinoses

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149276

Alteration of behavioural phenotype in mice by targeted disruption of the progranulin gene.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149276

Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149276

Synaptic Changes in the Thalamocortical System of Cathepsin D-Deficient Mice

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25022663

12 December 2020

inferred from PubMed ID database lookup

The neuronal ceroid lipofuscinoses: the same, but different?

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25022663

12 December 2020

inferred from PubMed ID database lookup

Common pathobiochemical hallmarks of progranulin-associated frontotemporal lobar degeneration and neuronal ceroid lipofuscinosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25022663

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1186/PREACCEPT-4589926441299369

1 reference

31 July 2017

1 reference

31 July 2017

1 reference