(Q34115325)

31 July 2017

A novel antisense long noncoding RNA within the IGF1R gene locus is imprinted in hematopoietic malignancies (English)

1 reference

31 July 2017

7

Jiuwei Cui

1 reference

31 July 2017

Jingnan Sun

1

1 reference

31 July 2017

Wei Li

2

1 reference

31 July 2017

Yunpeng Sun

3

1 reference

31 July 2017

Dehai Yu

4

1 reference

31 July 2017

Xue Wen

5

1 reference

31 July 2017

Hong Wang

6

1 reference

31 July 2017

Guanjun Wang

8

1 reference

31 July 2017

Andrew R Hoffman

9

1 reference

31 July 2017

Ji-Fan Hu

10

1 reference

31 July 2017

language of work or name

English

0 references

publication date

4 August 2014

1 reference

31 July 2017

Nucleic Acids Research

1 reference

31 July 2017

42

1 reference

31 July 2017

15

1 reference

31 July 2017

9588-9601

1 reference

Creative Commons Attribution 4.0 International

31 July 2017

start time

10 November 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Long noncoding RNA-mediated intrachromosomal interactions promote imprinting at the Kcnq1 locus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

Epigenetic reprogramming reverses the malignant epigenotype of the MMP/TIMP axis genes in tumor cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

Intrachromosomal looping is required for activation of endogenous pluripotency genes during reprogramming.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

The human imprintome: regulatory mechanisms, methods of ascertainment, and roles in disease susceptibility

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

Long noncoding RNAs: cellular address codes in development and disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

Structure and function of long noncoding RNAs in epigenetic regulation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

Epigenetic regulation by long noncoding RNAs

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

The role of the insulin-like growth factor-I receptor in malignancy: an update

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

Transcriptional silencing by hairpin RNAs complementary to a gene promoter

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

Regulation of chromatin structure by long noncoding RNAs: focus on natural antisense transcripts

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

Targeting insulin-like growth factor in breast cancer therapeutics

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

The insulin and insulin-like growth factor receptor family in neoplasia: an update

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

Targeting the insulin-like growth factor 1 receptor (IGF1R) signaling pathway for cancer therapy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

Blockade of insulin-like growth factor type-1 receptor with cixutumumab (IMC-A12): a novel approach to treatment for multiple cancers

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

The inactive X chromosome adopts a unique three-dimensional conformation that is dependent on Xist RNA.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

Interruption of intrachromosomal looping by CCCTC binding factor decoy proteins abrogates genomic imprinting of human insulin-like growth factor II.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

No-nonsense functions for long noncoding RNAs

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

Small molecule inhibitors of the IGF-1R/IR axis for the treatment of cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

The emerging role of RNA in the regulation of gene transcription in human cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

Targeting the insulin-like growth factor network in cancer therapy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

Insulin-like growth factor system and sporadic malignant melanoma.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

Long noncoding RNA as modular scaffold of histone modification complexes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

Characterization of the RNA content of chromatin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

Poised transcription factories prime silent uPA gene prior to activation.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

Autocrine IGF-1/IGF-1R signaling is responsible for constitutive PI3K/Akt activation in acute myeloid leukemia: therapeutic value of neutralizing anti-IGF-1R antibody

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

Expression of insulin receptor isoform A and insulin-like growth factor-1 receptor in human acute myelogenous leukemia: effect of the dual-receptor inhibitor BMS-536924 in vitro

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

Genomic imprinting: employing and avoiding epigenetic processes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

CTCF regulates allelic expression of Igf2 by orchestrating a promoter-polycomb repressive complex 2 intrachromosomal loop

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

Inducible packaging cells for large-scale production of lentiviral vectors in serum-free suspension culture

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

Eukaryotic regulatory RNAs: an answer to the 'genome complexity' conundrum

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

Correction of aberrant imprinting of IGF2 in human tumors by nuclear transfer-induced epigenetic reprogramming

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

Inhibiting gene expression at transcription start sites in chromosomal DNA with antigene RNAs

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

Transcriptional interference--a crash course

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

An antisense RNA regulates the bidirectional silencing property of the Kcnq1 imprinting control region

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

Epigenetic regulation of the taxol resistance-associated gene TRAG-3 in human tumors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

Capturing chromosome conformation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

The non-coding Air RNA is required for silencing autosomal imprinted genes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

Chromosomal silencing and localization are mediated by different domains of Xist RNA.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

Competition--a common motif for the imprinting mechanism?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

X chromosome inactivation is mediated by Xist RNA stabilization

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

Regulation of insulin preRNA splicing by glucose

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

In vivo degradation of RNA polymerase II largest subunit triggered by alpha-amanitin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

Promoter-specific modulation of insulin-like growth factor II genomic imprinting by inhibitors of DNA methylation.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

Gametic imprinting in mammals

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

The mouse insulin-like growth factor type-2 receptor is imprinted and closely linked to the Tme locus

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

Plasma and tissue insulin-like growth factor-I receptor (IGF-IR) as a prognostic marker for prostate cancer and anti-IGF-IR agents as novel therapeutic strategy for refractory cases: a review

28 July 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU549

The proliferating role of insulin and insulin-like growth factors in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU549

Survival of acute myeloid leukemia cells requires PI3 kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU549

Autocrine insulin-like growth factor-I signaling promotes growth and survival of human acute myeloid leukemia cells via the phosphoinositide 3-kinase/Akt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU549

Insulin is a potent myeloma cell growth factor through insulin/IGF-1 hybrid receptor activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU549

High-level IGF1R expression is required for leukemia-initiating cell activity in T-ALL and is supported by Notch signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU549

Two distinct mechanisms of silencing by the KvDMR1 imprinting control region

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU549

A differentially methylated region within the gene Kcnq1 functions as an imprinted promoter and silencer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU549

Tissue-specific imprinting of the mouse insulin-like growth factor II receptor gene correlates with differential allele-specific DNA methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU549

Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signal.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU549

Imprinted expression of the Igf2r gene depends on an intronic CpG island.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU549

Lack of reciprocal genomic imprinting of sense and antisense RNA of mouse insulin-like growth factor II receptor in the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU549

Silencing by imprinted noncoding RNAs: is transcription the answer?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU549

Higher order chromatin structure at the X-inactivation center via looping DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU549

A complex deoxyribonucleic acid looping configuration associated with the silencing of the maternal Igf2 allele

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU549

Interaction between differentially methylated regions partitions the imprinted genes Igf2 and H19 into parent-specific chromatin loops

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU549

Imprinting of the mouse Igf2r gene depends on an intronic CpG island.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU549

PI3-kinase/Akt is constitutively active in primary acute myeloid leukaemia cells and regulates survival and chemoresistance via NF-kappaB, Mapkinase and p53 pathways

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

Allele-specific histone acetylation accompanies genomic imprinting of the insulin-like growth factor II receptor gene

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

Differential biallelic activation of three insulin-like growth factor II promoters in the mouse central nervous system.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4150754

Airn transcriptional overlap, but not its lncRNA products, induces imprinted Igf2r silencing

28 October 2018

1 reference

12 December 2020

Increased expression of insulin-like growth factor i is associated with Ara-C resistance in leukemia

1 reference

12 December 2020

Insulin-like growth factor I is a dual effector of multiple myeloma cell growth

1 reference

12 December 2020

α-Amanitin: A specific inhibitor of one of two DNA-dependent RNA polymerase activities from calf thymus

1 reference

12 December 2020

Specific Inhibition of Nuclear RNA Polymerase II by α-Amanitin

1 reference

12 December 2020

The insulin-like growth factor 1 receptor gene is normally biallelically expressed in human juvenile tissue and tumours

1 reference

12 December 2020

Human insulin-like growth factor type I and type II receptors are not imprinted

1 reference

12 December 2020

Phase I study of the anti insulin-like growth factor 1 receptor (IGF-1R) monoclonal antibody, AVE1642, as single agent and in combination with bortezomib in patients with relapsed multiple myeloma

1 reference

12 December 2020

Identifiers

DOI

10.1093/NAR/GKU549

1 reference

31 July 2017

1 reference

31 July 2017

1 reference