(Q34123368)

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Genetic polymorphisms and drug interactions modulating CYP2D6 and CYP3A activities have a major effect on oxycodone analgesic efficacy and safety

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scholarly article

1 reference

Europe PubMed Central

31 July 2017

Genetic polymorphisms and drug interactions modulating CYP2D6 and CYP3A activities have a major effect on oxycodone analgesic efficacy and safety (English)

1 reference

Europe PubMed Central

31 July 2017

Denis Hochstrasser

8

object named as

D Hochstrasser

1 reference

Europe PubMed Central

31 July 2017

author name string

C F Samer

1

1 reference

Europe PubMed Central

31 July 2017

Y Daali

2

1 reference

Europe PubMed Central

31 July 2017

M Wagner

3

1 reference

Europe PubMed Central

31 July 2017

G Hopfgartner

4

1 reference

Europe PubMed Central

31 July 2017

C B Eap

5

1 reference

Europe PubMed Central

31 July 2017

M C Rebsamen

6

1 reference

Europe PubMed Central

31 July 2017

M F Rossier

7

1 reference

Europe PubMed Central

31 July 2017

P Dayer

9

1 reference

Europe PubMed Central

31 July 2017

J A Desmeules

10

1 reference

Europe PubMed Central

31 July 2017

language of work or name

0 references

publication date

1 June 2010

1 reference

Europe PubMed Central

31 July 2017

British Journal of Pharmacology

1 reference

Europe PubMed Central

31 July 2017

160

1 reference

Europe PubMed Central

31 July 2017

919-930

1 reference

Europe PubMed Central

31 July 2017

4

1 reference

Europe PubMed Central

31 July 2017

Rifampin greatly reduces the plasma concentrations of intravenous and oral oxycodone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935998

5 July 2018

Complicated pain management in a CYP450 2D6 poor metabolizer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935998

5 July 2018

Pharmacokinetics and pharmacodynamics of oral oxycodone in healthy human subjects: role of circulating active metabolites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935998

5 July 2018

The lower limb flexion reflex in humans

1 reference

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5 July 2018

Oxycodone. Pharmacological profile and clinical data in chronic pain management.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935998

5 July 2018

Codeine intoxication associated with ultrarapid CYP2D6 metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935998

5 July 2018

Quantitative contribution of CYP2D6 and CYP3A to oxycodone metabolism in human liver and intestinal microsomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935998

5 July 2018

Activation of G-Proteins by Morphine and Codeine Congeners: Insights to the Relevance of O- and N-Demethylated Metabolites at μ- and δ-Opioid Receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935998

5 July 2018

Normal-release and controlled-release oxycodone: pharmacokinetics, pharmacodynamics, and controversy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935998

5 July 2018

Interaction of cytochrome P450 3A inhibitors with P-glycoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935998

5 July 2018

Visual hallucination and tremor induced by sertraline and oxycodone in a bone marrow transplant patient

1 reference

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5 July 2018

The intrinsic antinociceptive effects of oxycodone appear to be kappa-opioid receptor mediated

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935998

5 July 2018

Attenuation of morphine-induced delirium in palliative care by substitution with infusion of oxycodone.

1 reference

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5 July 2018

Inhibition by fluoxetine of cytochrome P450 2D6 activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935998

5 July 2018

Psychomotor function and psychoactive drugs

1 reference

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5 July 2018

Morphine and ibuprofen compared using the cold pressor test

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935998

5 July 2018

Studies of heat pain sensation in man: perception thresholds, rate of stimulus rise and reaction time.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935998

5 July 2018

Mu receptor binding of some commonly used opioids and their metabolites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935998

5 July 2018

Opiate receptor binding affected differentially by opiates and opioid peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935998

5 July 2018

Method for quantitative estimation of thermal thresholds in patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935998

5 July 2018

Comparison of epidural morphine and oxycodone for pain after abdominal surgery.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.00673.X

21 January 2018

Development and validation of a chemical hydrolysis method for dextromethorphan and dextrophan determination in urine samples: application to the assessment of CYP2D6 activity in fibromyalgia patients

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.00673.X

21 January 2018

Oral administration of a low dose of midazolam (75 microg) as an in vivo probe for CYP3A activity

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.00673.X

21 January 2018

Cytochrome P4502D6 (CYP2D6) gene locus heterogeneity: characterization of gene duplication events.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.00673.X

21 January 2018

Voriconazole drastically increases exposure to oral oxycodone

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.00673.X

21 January 2018

Effects of blocking CYP2D6 on the pharmacokinetics and pharmacodynamics of oxycodone.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.00673.X

21 January 2018

Negative urine opioid screening caused by rifampin-mediated induction of oxycodone hepatic metabolism

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.00673.X

21 January 2018

Characterization and validation of a pharmacokinetic model for controlled-release oxycodone

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.00673.X

21 January 2018

A review of oxycodone's clinical pharmacokinetics and pharmacodynamics

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.00673.X

21 January 2018

The AmpliChip CYP450 test: cytochrome P450 2D6 genotype assessment and phenotype prediction

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.00673.X

21 January 2018

Genetic polymorphism and drug interactions: their importance in the treatment of pain

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.00673.X

21 January 2018

Impact of CYP2C19 phenotypes on escitalopram metabolism and an evaluation of pupillometry as a serotonergic biomarker.

1 reference

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28 October 2018

The hypoalgesic effect of oxycodone in human experimental pain models in relation to the CYP2D6 oxidation polymorphism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935998

28 October 2018

Oxycodone induces overexpression of P-glycoprotein (ABCB1) and affects paclitaxel's tissue distribution in Sprague Dawley rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935998

28 October 2018

Involvement of mu1-opioid receptor on oxycodone-induced antinociception in diabetic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935998

28 October 2018

Antinociception by spinal and systemic oxycodone: why does the route make a difference? In vitro and in vivo studies in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935998

28 October 2018

Response to hydrocodone, codeine and oxycodone in a CYP2D6 poor metabolizer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935998

28 October 2018

Discriminative stimulus, reinforcing, physical dependence, and antinociceptive effects of oxycodone in mice, rats, and rhesus monkeys

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935998

28 October 2018

Adverse drug reactions to oxycodone and hydrocodone in CYP2D6 ultrarapid metabolizers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935998

28 October 2018

The influence of pharmacogenetics on opioid analgesia: studies with codeine and oxycodone in the Sprague-Dawley/Dark Agouti rat model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935998

28 October 2018

Oxymorphone metabolism and urinary excretion in human, rat, guinea pig, rabbit, and dog

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935998

28 October 2018

Morphine, Oxycodone, Methadone and Its Enantiomers in Different Models of Nociception in the Rat

1 reference

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21 January 2018

Inhibition of UDP-glucuronosyltransferase 2b7-catalyzed morphine glucuronidation by ketoconazole: dual mechanisms involving a novel noncompetitive mode

1 reference

https://pubmed.ncbi.nlm.nih.gov/20590588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxycodone???s Mechanism of Action and Potency Differences after Spinal and Systemic Routes of Administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/20590588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of CYP2D6 and CYP3A activities on the pharmacokinetics of immediate release oxycodone

1 reference

https://pubmed.ncbi.nlm.nih.gov/20590588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Individualizing analgesic prescription Part I: pharmacogenetics of opioid analgesics

1 reference

https://pubmed.ncbi.nlm.nih.gov/20590588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic-pharmacodynamic relationships of controlled-release oxycodone

1 reference

https://pubmed.ncbi.nlm.nih.gov/20590588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacogenetic determinants of codeine induction by rifampin: the impact on codeine's respiratory, psychomotor and miotic effects

1 reference

https://pubmed.ncbi.nlm.nih.gov/20590588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1476-5381.2010.00673.X

1 reference

Europe PubMed Central

31 July 2017

1 reference

Europe PubMed Central

31 July 2017

1 reference

Europe PubMed Central

31 July 2017

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