(Q34123770)

31 July 2017

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title

Glutathione transferases as mediators of signaling pathways involved in cell proliferation and cell death (English)

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31 July 2017

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E Laborde

1

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31 July 2017

publication date

2 July 2010

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Cell Death & Differentiation

31 July 2017

published in

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31 July 2017

volume

17

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31 July 2017

issue

9

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31 July 2017

page(s)

1373-1380

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https://scigraph.springernature.com/pub.10.1038/cdd.2010.80

31 July 2017

exact match

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cites work

Zeta, a novel class of glutathione transferases in a range of species from plants to humans

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Nomenclature for human glutathione transferases

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Two distinct forms of glutathione transferase from human foetal liver. Purification and comparison with isoenzymes isolated from adult liver and placenta

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Studies of the development of basic, neutral and acidic isoenzymes of glutathione S-transferase in human liver, adrenal, kidney and spleen

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Glutathione transferases as targets for cancer therapy.

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The glutathione-binding site in glutathione S-transferases. Investigation of the cysteinyl, glycyl and gamma-glutamyl domains

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Glutathione-doxorubicin conjugate expresses potent cytotoxicity by suppression of glutathione S-transferase activity: comparison between doxorubicin-sensitive and -resistant rat hepatoma cells

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Ligandin: a Hepatic Protein which Binds Steroids, Bilirubin, Carcinogens and a Number of Exogenous Organic Anions

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7 January 2021

The identity of glutathione S-transferase B with ligandin, a major binding protein of liver

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7 January 2021

Identification of mu-class glutathione transferases M2-2 and M3-3 as cytosolic prostaglandin E synthases in the human brain

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7 January 2021

Human glutathione transferase A3-3, a highly efficient catalyst of double-bond isomerization in the biosynthetic pathway of steroid hormones

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7 January 2021

4-Hydroxyalk-2-enals are substrates for glutathione transferase

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7 January 2021

Regulation of 4-hydroxynonenal-mediated signaling by glutathione S-transferases

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7 January 2021

Proposed intracellular regulatory functions of glutathione transferases by recognition and binding to S-glutathiolated proteins

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7 January 2021

The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance

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7 January 2021

Genetic polymorphism and function of glutathione S-transferases in tumor drug resistance.

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https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Regulation of JNK signaling by GSTp

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https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Glutathione S-transferase mu modulates the stress-activated signals by suppressing apoptosis signal-regulating kinase 1

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https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Negative regulation of MEKK1-induced signaling by glutathione S-transferase Mu.

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https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Human GSTA1-1 reduces c-Jun N-terminal kinase signalling and apoptosis in Caco-2 cells

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https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Glutathione transferases

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Identification of three classes of cytosolic glutathione transferase common to several mammalian species: correlation between structural data and enzymatic properties

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Theta, a new class of glutathione transferases purified from rat and man

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Nomenclature for mammalian soluble glutathione transferases

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The human glutathione S-transferases: developmental aspects of the GST1, GST2, and GST3 loci.

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Expression of class Pi glutathione transferase in human malignant melanoma cells

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The polymorphic human glutathione transferase T1-1, the most efficient glutathione transferase in the denitrosation and inactivation of the anticancer drug 1,3-bis(2-chloroethyl)-1-nitrosourea

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https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Role of glutathione in cellular resistance to alkylating agents

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7 January 2021

Coordinated action of glutathione S-transferases (GSTs) and multidrug resistance protein 1 (MRP1) in antineoplastic drug detoxification. Mechanism of GST A1-1- and MRP1-associated resistance to chlorambucil in MCF7 breast carcinoma cells

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7 January 2021

From JNK to pay dirt: jun kinases, their biochemistry, physiology and clinical importance

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Identification of cysteine residues involved in disulfide formation in the inactivation of glutathione transferase P-form by hydrogen peroxide

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7 January 2021

Glutathione S-transferase P1-1 (GSTP1-1) inhibits c-Jun N-terminal kinase (JNK1) signaling through interaction with the C terminus

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https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Monomer-dimer equilibrium in glutathione transferases: a critical re-examination.

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https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Increased constitutive c-Jun N-terminal kinase signaling in mice lacking glutathione S-transferase Pi

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https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Human glutathione S-transferase P1-1 interacts with TRAF2 and regulates TRAF2-ASK1 signals

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https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

The chemistry and biology of inhibitors and pro-drugs targeted to glutathione S-transferases

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https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Advance in antitumor agents targeting glutathione-S-transferase

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https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Glutathione analogues in cancer treatment

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https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Ligand-based protein alignment and isozyme specificity of glutathione S-transferase inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Isozyme-specific glutathione-S-transferase inhibitors: design and synthesis

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

The structures of human glutathione transferase P1-1 in complex with glutathione and various inhibitors at high resolution

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Transport of glutathione diethyl ester into human cells

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Isozyme-specific glutathione S-transferase inhibitors potentiate drug sensitivity in cultured human tumor cell lines

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Increased myeloproliferation in glutathione S-transferase pi-deficient mice is associated with a deregulation of JNK and Janus kinase/STAT pathways

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Phase 1-2a multicenter dose-escalation study of ezatiostat hydrochloride liposomes for injection (Telintra, TLK199), a novel glutathione analog prodrug in patients with myelodysplastic syndrome.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Phase 1 multicenter dose-escalation study of ezatiostat hydrochloride (TLK199 tablets), a novel glutathione analog prodrug, in patients with myelodysplastic syndrome.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Molecular cloning, characterization, and expression in Escherichia coli of full-length cDNAs of three human glutathione S-transferase Pi gene variants. Evidence for differential catalytic activity of the encoded proteins

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Structure of the human allelic glutathione S-transferase-pi gene variant, hGSTP1 C, cloned from a glioblastoma multiforme cell line

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Human glutathione S-transferase P1 polymorphisms: relationship to lung tissue enzyme activity and population frequency distribution

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Differential effects of glutathione S-transferase pi (GSTP1) haplotypes on cell proliferation and apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

The human glutathione transferase P1-1 specific inhibitor TER 117 designed for overcoming cytostatic-drug resistance is also a strong inhibitor of glyoxalase I

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Peptidomimetic glutathione analogues as novel gammaGT stable GST inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Peptide-bond modified glutathione conjugate analogs modulate GSTpi function in GSH-conjugation, drug sensitivity and JNK signaling

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Synthesis and activity of novel glutathione analogues containing an urethane backbone linkage.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Phosphono analogues of glutathione as new inhibitors of glutathione S-transferases

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Phosphono analogs of glutathione: inhibition of glutathione transferases, metabolic stability, and uptake by cancer cells.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Significance of an unusually low Km for glutathione in glutathione transferases of the alpha, mu and pi classes

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Suppression of GST-P by treatment with glutathione-doxorubicin conjugate induces potent apoptosis in rat hepatoma cells

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Conformational change in the active center region of GST P1-1, due to binding of a synthetic conjugate of DXR with GSH, enhanced JNK-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Novel class of bivalent glutathione S-transferase inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Ethacrynic acid and its glutathione conjugate as inhibitors of glutathione S-transferases

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Detection of drug-induced apoptosis and necrosis in human cervical carcinoma cells using 1H NMR spectroscopy

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Characterization of cell death induced by ethacrynic acid in a human colon cancer cell line DLD‐1 and suppression by N‐acetyl‐l‐cysteine

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

7-Nitro-2,1,3-benzoxadiazole derivatives, a new class of suicide inhibitors for glutathione S-transferases. Mechanism of action of potential anticancer drugs

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Proapoptotic activity of new glutathione S-transferase inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Structural basis for the binding of the anticancer compound 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol to human glutathione s-transferases

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

In vitro and in vivo efficacy of 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) on human melanoma

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Thiazolides inhibit growth and induce glutathione-S-transferase Pi (GSTP1)-dependent cell death in human colon cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Haloenol lactone is a new isozyme-selective and active site-directed inactivator of glutathione S-transferase

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Mechanistic studies of inactivation of glutathione S-transferase Pi isozyme by a haloenol lactone derivative

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Human renal UOK130 tumor cells: a drug resistant cell line with highly selective over-expression of glutathione S-transferase-pi isozyme

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Critical role of oxidative stress and sustained JNK activation in aloe-emodin-mediated apoptotic cell death in human hepatoma cells.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Benastatins A and B, new inhibitors of glutathione S-transferase, produced by Streptomyces sp. MI384-DF12. I. Taxonomy, production, isolation, physico-chemical properties and biological activities.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Benastatins C and D, new inhibitors of glutathione S-transferase, produced by Streptomyces sp. MI384-DF12. Production, isolation, structure determination and biological activities

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.80

7 January 2021

Identifiers

DOI

10.1038/CDD.2010.80

1 reference

31 July 2017

1 reference