(Q34130512)

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An MMP13-selective inhibitor delays primary tumor growth and the onset of tumor-associated osteolytic lesions in experimental models of breast cancer

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Europe PubMed Central

PubMed publication ID

31 July 2017

An MMP13-selective inhibitor delays primary tumor growth and the onset of tumor-associated osteolytic lesions in experimental models of breast cancer (English)

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Europe PubMed Central

PubMed publication ID

31 July 2017

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Erik W. Thompson

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Erik W Thompson

9

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Manisha Shah

1

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Europe PubMed Central

PubMed publication ID

31 July 2017

Dexing Huang

2

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Europe PubMed Central

PubMed publication ID

31 July 2017

Tony Blick

3

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Andrea Connor

4

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Lawrence A Reiter

5

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Joel R Hardink

6

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Conor C Lynch

7

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Europe PubMed Central

PubMed publication ID

31 July 2017

Mark Waltham

8

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Europe PubMed Central

PubMed publication ID

31 July 2017

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publication date

11 January 2012

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Europe PubMed Central

PubMed publication ID

31 July 2017

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

7

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Europe PubMed Central

PubMed publication ID

31 July 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

e29615

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

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Creative Commons Attribution 4.0 International

11 January 2012

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April 2022 Public Data File from Crossref

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Microarray and proteomic analysis of breast cancer cell and osteoblast co-cultures: role of osteoblast matrix metalloproteinase (MMP)-13 in bone metastasis

1 reference

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5 July 2018

Matrix metalloproteinases as master regulators of the vicious cycle of bone metastasis

1 reference

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5 July 2018

Matrix metalloproteinase (MMP)-13 regulates mammary tumor-induced osteolysis by activating MMP9 and transforming growth factor-beta signaling at the tumor-bone interface

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256168

5 July 2018

Matrix metalloproteinase 13-deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256168

5 July 2018

MMP13 as a stromal mediator in controlling persistent angiogenesis in skin carcinoma

1 reference

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5 July 2018

Osteoclast-derived matrix metalloproteinase-7, but not matrix metalloproteinase-9, contributes to tumor-induced osteolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256168

5 July 2018

MMP-13 plays a role in keratinocyte migration, angiogenesis, and contraction in mouse skin wound healing.

1 reference

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5 July 2018

Collagenase expression and activity in the stromal cells from giant cell tumour of bone.

1 reference

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5 July 2018

MMP-13 is over-expressed in renal cell carcinoma bone metastasis and is induced by TGF-beta1.

1 reference

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5 July 2018

Matrix metalloproteinases and bone

1 reference

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5 July 2018

Exploring the anti-tumour activity of bisphosphonates in early breast cancer.

1 reference

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5 July 2018

Tumor-derived matrix metalloproteinase-13 (MMP-13) correlates with poor prognoses of invasive breast cancer

1 reference

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5 July 2018

Proteases as modulators of tumor-stromal interaction: primary tumors to bone metastases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256168

5 July 2018

Role of matrix metalloproteinase 13 in both endochondral and intramembranous ossification during skeletal regeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256168

5 July 2018

The other side of MMPs: protective roles in tumor progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256168

5 July 2018

Matrix metalloproteinase inhibitors: new challenges in the era of post broad-spectrum inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256168

5 July 2018

Discovery and characterization of a novel inhibitor of matrix metalloprotease-13 that reduces cartilage damage in vivo without joint fibroplasia side effects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256168

5 July 2018

Ten years in the life of an enzyme: the story of the human MMP-13 (collagenase-3).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256168

5 July 2018

Bisphosphonate-associated osteonecrosis: a long-term complication of bisphosphonate treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256168

5 July 2018

Towards third generation matrix metalloproteinase inhibitors for cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256168

5 July 2018

The importance of estimating the therapeutic index in the development of matrix metalloproteinase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256168

5 July 2018

Zoledronic acid suppresses lung metastases and prolongs overall survival of osteosarcoma-bearing mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256168

5 July 2018

Antisense-mediated suppression of hyaluronan synthase 2 inhibits the tumorigenesis and progression of breast cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256168

5 July 2018

Genomic analysis of a spontaneous model of breast cancer metastasis to bone reveals a role for the extracellular matrix.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256168

5 July 2018

Critical roles for collagenase-3 (Mmp13) in development of growth plate cartilage and in endochondral ossification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256168

5 July 2018

Upregulation of matrix metalloproteinases (MMPs) in breast cancer xenografts: a major induction of stromal MMP-13.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256168

5 July 2018

Altered endochondral bone development in matrix metalloproteinase 13-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256168

5 July 2018

Transfection of MDA-MB-231 human breast carcinoma cells with bone sialoprotein (BSP) stimulates migration and invasion in vitro and growth of primary and secondary tumors in nude mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256168

5 July 2018

Nmp4/CIZ regulation of matrix metalloproteinase 13 (MMP-13) response to parathyroid hormone in osteoblasts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256168

5 July 2018

Matrix metalloproteinases (MMP) and cathepsin K contribute differently to osteoclastic activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256168

5 July 2018

Role of RANKL-induced osteoclast formation and MMP-dependent matrix degradation in bone destruction by breast cancer metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256168

5 July 2018

Matrix metalloproteinase 13 activity is associated with poor prognosis in colorectal cancer

1 reference

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5 July 2018

Postnatal expression in hyaline cartilage of constitutively active human collagenase-3 (MMP-13) induces osteoarthritis in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256168

5 July 2018

Collagenase-3 (MMP-13) and integral membrane protein 2a (Itm2a) are marker genes of chondrogenic/osteoblastic cells in bone formation: sequential temporal, and spatial expression of Itm2a, alkaline phosphatase, MMP-13, and osteocalcin in the mouse.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256168

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Effects of angiogenesis inhibitors on multistage carcinogenesis in mice

1 reference

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5 July 2018

Crystal structures of MMP-1 and -13 reveal the structural basis for selectivity of collagenase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256168

5 July 2018

Identification of the membrane-type matrix metalloproteinase MT1-MMP in osteoclasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256168

5 July 2018

Biochemical characterization of human collagenase-3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256168

5 July 2018

Molecular cloning of a possible cysteine proteinase predominantly expressed in osteoclasts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256168

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Bisphosphonate risedronate reduces metastatic human breast cancer burden in bone in nude mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256168

5 July 2018

Parathyroid hormone induces transcription of collagenase in rat osteoblastic cells by a mechanism using cyclic adenosine 3',5'-monophosphate and requiring protein synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256168

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Tumour microenvironment - opinion: validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029615

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Matrix metalloproteinase-13 expression is associated with bone marrow microinvolvement and prognosis in non-small cell lung cancer.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029615

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The expression of collagenase 3 (MMP-13) mRNA in the synovial tissue is associated with histopathologic type II synovitis in rheumatoid arthritis.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029615

21 January 2018

Potent pyrimidinetrione-based inhibitors of MMP-13 with enhanced selectivity over MMP-14.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029615

21 January 2018

A novel orthotopic model of breast cancer metastasis to bone.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029615

21 January 2018

Fluorescence-based staining for tartrate-resistant acidic phosphatase (TRAP) in osteoclasts combined with other fluorescent dyes and protocols.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029615

21 January 2018

Stromal Expression of MMP-13 Is Required for Melanoma Invasion and Metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22253746

12 December 2020

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The effects of selective inhibitors of matrix metalloproteinases (MMPs) on bone resorption and the identification of MMPs and TIMP-1 in isolated osteoclasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/22253746

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A scrutiny of matrix metalloproteinases in osteoclasts: evidence for heterogeneity and for the presence of MMPs synthesized by other cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22253746

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MMP-9 secretion and MMP-2 activation distinguish invasive and metastatic sublines of a mouse mammary carcinoma system showing epithelial-mesenchymal transition traits

1 reference

https://pubmed.ncbi.nlm.nih.gov/22253746

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based on heuristic

inferred from PubMed ID database lookup

Loss of MMP 13 attenuates murine hepatic injury and fibrosis during cholestasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22253746

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potent, selective pyrimidinetrione-based inhibitors of MMP-13

1 reference

https://pubmed.ncbi.nlm.nih.gov/22253746

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation between extent of osteolytic damage and metastatic burden of human breast cancer metastasis in nude mice: real-time PCR quantitation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22253746

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix metalloproteinases as diagnostic (MMP-13) and prognostic (MMP-2, MMP-9) markers of prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22253746

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based on heuristic

inferred from PubMed ID database lookup

Collagenase-3 expression in breast myofibroblasts as a molecular marker of transition of ductal carcinoma in situ lesions to invasive ductal carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/22253746

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0029615

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

2012PLoSO...729615S

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PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

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