(Q34138890)

31 July 2017

title

Dual functions of the trans-2-enoyl-CoA reductase TER in the sphingosine 1-phosphate metabolic pathway and in fatty acid elongation (English)

1 reference

Trans-2,3-enoyl-CoA reductase

31 July 2017

0 references

1 reference

sphingolipid metabolic process

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

3

Akio Kihara

1 reference

31 July 2017

Takeshi Wakashima

1

1 reference

31 July 2017

Kensuke Abe

series ordinal

2

1 reference

31 July 2017

language of work or name

English

0 references

publication date

21 July 2014

1 reference

Journal of Biological Chemistry

31 July 2017

number of pages

13

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

31 July 2017

volume

289

1 reference

31 July 2017

issue

36

1 reference

31 July 2017

page(s)

24736-24748

1 reference

Metabolism of very long-chain Fatty acids: genes and pathophysiology

31 July 2017

cites work

1 reference

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Mutation for nonsyndromic mental retardation in the trans-2-enoyl-CoA reductase TER gene involved in fatty acid elongation impairs the enzyme activity and stability, leading to change in sphingolipid profile

5 July 2018

1 reference

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Sphingolipids as modulators of membrane proteins

5 July 2018

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Sphingosine 1-phosphate is a key metabolite linking sphingolipids to glycerophospholipids

5 July 2018

1 reference

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Fingolimod: direct CNS effects of sphingosine 1-phosphate (S1P) receptor modulation and implications in multiple sclerosis therapy

5 July 2018

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5 July 2018

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Very long-chain fatty acids: elongation, physiology and related disorders

5 July 2018

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Sphingolipid signaling in metabolic disorders

5 July 2018

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The Sjögren-Larsson syndrome gene encodes a hexadecenal dehydrogenase of the sphingosine 1-phosphate degradation pathway.

5 July 2018

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5 July 2018

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Sphingosine 1-phosphate (S1P) lyase deficiency increases sphingolipid formation via recycling at the expense of de novo biosynthesis in neurons

5 July 2018

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Central nervous system dysfunction in a mouse model of FA2H deficiency

5 July 2018

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5 July 2018

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Exome sequencing reveals a novel mutation for autosomal recessive non-syndromic mental retardation in the TECR gene on chromosome 19p13

5 July 2018

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Sphingosine-1-phosphate lyase deficiency produces a pro-inflammatory response while impairing neutrophil trafficking.

5 July 2018

1 reference

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A critical role for ceramide synthase 2 in liver homeostasis: II. insights into molecular changes leading to hepatopathy

5 July 2018

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Sphingosine 1-phosphate lyase deficiency disrupts lipid homeostasis in liver

5 July 2018

1 reference

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Significance of glycosphingolipid fatty acid chain length on membrane microdomain-mediated signal transduction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155643

Adult ceramide synthase 2 (CERS2)-deficient mice exhibit myelin sheath defects, cerebellar degeneration, and hepatocarcinomas

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155643

Global analysis of the yeast lipidome by quantitative shotgun mass spectrometry

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155643

Incomplete inhibition of sphingosine 1-phosphate lyase modulates immune system function yet prevents early lethality and non-lymphoid lesions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155643

Tracking microdomain dynamics in cell membranes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155643

Production and release of sphingosine 1-phosphate and the phosphorylated form of the immunomodulator FTY720.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155643

2-Hydroxy-ceramide synthesis by ceramide synthase family: enzymatic basis for the preference of FA chain length

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155643

Mammalian long-chain acyl-CoA synthetases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155643

Membrane topology and essential amino acid residues of Phs1, a 3-hydroxyacyl-CoA dehydratase involved in very long-chain fatty acid elongation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155643

Characterization of ceramide synthase 2: tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate

5 July 2018

1 reference

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Dual subcellular localization in the endoplasmic reticulum and peroxisomes and a vital role in protecting against oxidative stress of fatty aldehyde dehydrogenase are achieved by alternative splicing

5 July 2018

1 reference

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Metabolism and biological functions of two phosphorylated sphingolipids, sphingosine 1-phosphate and ceramide 1-phosphate

5 July 2018

1 reference

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Sjögren-Larsson syndrome: molecular genetics and biochemical pathogenesis of fatty aldehyde dehydrogenase deficiency

5 July 2018

1 reference

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Yeast sphingolipids do not need to contain very long chain fatty acids

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155643

Long-chain base kinase Lcb4 Is anchored to the membrane through its palmitoylation by Akr1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155643

Sphingosine-1-phosphate lyase SPL is an endoplasmic reticulum-resident, integral membrane protein with the pyridoxal 5'-phosphate binding domain exposed to the cytosol.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155643

Physiological and pathological actions of sphingosine 1-phosphate.

5 July 2018

1 reference

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Mammalian wax biosynthesis. I. Identification of two fatty acyl-Coenzyme A reductases with different substrate specificities and tissue distributions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155643

Phosphorylation of the immunomodulatory drug FTY720 by sphingosine kinases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155643

Sphingosine-1-phosphate: an enigmatic signalling lipid

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155643

Identification of two mammalian reductases involved in the two-carbon fatty acyl elongation cascade

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155643

Tsc13p is required for fatty acid elongation and localizes to a novel structure at the nuclear-vacuolar interface in Saccharomyces cerevisiae

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155643

Designer deletion strains derived from Saccharomyces cerevisiae S288C: a useful set of strains and plasmids for PCR-mediated gene disruption and other applications

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155643

Identification of the first mammalian sphingosine phosphate lyase gene and its functional expression in yeast

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155643

Lipid remodeling leads to the introduction and exchange of defined ceramides on GPI proteins in the ER and Golgi of Saccharomyces cerevisiae

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155643

ELO2 and ELO3, homologues of the Saccharomyces cerevisiae ELO1 gene, function in fatty acid elongation and are required for sphingolipid formation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155643

Mammalian mitochondrial beta-oxidation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155643

Metabolism of Sphingosine Bases, XIV. Sphinganine (Dihydrosphingosine), an Effective Donor of the Alk-1’-enyl Chain of Plasmalogens

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155643

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155643

Discontinued postnatal thymocyte development in sphingosine 1-phosphate-lyase-deficient mice.

5 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M114.571869

Identification of acyl-CoA synthetases involved in the mammalian sphingosine 1-phosphate metabolic pathway

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M114.571869

Neutral ceramidase encoded by the Asah2 gene is essential for the intestinal degradation of sphingolipids

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M114.571869

An essential function of sphingolipids in yeast cell division

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155643

Functional analysis of yeast essential genes using a promoter-substitution cassette and the tetracycline-regulatable dual expression system.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155643

Metabolism of sphingosine bases, I. Degradation and incorporation of (3-14C)erythro-DL-dihydrosphingosine and (7-3H2)erythro-DL-sphingosine into sphingolipids of rat liver

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25049234

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M114.571869

1 reference

31 July 2017

1 reference

31 July 2017

1 reference