(Q34139050)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25059668%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

title

Amino acid derivatives as bitter taste receptor (T2R) blockers (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25059668%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25059668%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Prashen Chelikani

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25059668%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

author name string

Tyler Sobotkiewicz

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25059668%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Rohini Billakanti

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25059668%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Rajinder P Bhullar

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25059668%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Michele C Loewen

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25059668%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

language of work or name

English

0 references

publication date

24 July 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25059668%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

10 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25059668%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

volume

289

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25059668%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

issue

36

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25059668%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

page(s)

25054-25066

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25059668%20AND%20SRC:MED&resulttype=core&format=json

Constitutive activity of bitter taste receptors (T2Rs).

10 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155672

6-methoxyflavanones as bitter taste receptor blockers for hTAS2R39

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155672

Muscarinic acetylcholine receptor X-ray structures: potential implications for drug development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155672

Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155672

Quantitative versus qualitative data: the numerical dimensions of drug action

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155672

The human bitter taste receptor TAS2R10 is tailored to accommodate numerous diverse ligands.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155672

Extraoral bitter taste receptors as mediators of off-target drug effects

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155672

Bitter taste receptor research comes of age: from characterization to modulation of TAS2Rs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155672

Constitutively active mutant gives novel insights into the mechanism of bitter taste receptor activation.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155672

Site-directed mutations and the polymorphic variant Ala160Thr in the human thromboxane receptor uncover a structural role for transmembrane helix 4

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155672

Diversity and modularity of G protein-coupled receptor structures

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155672

A gustotopic map of taste qualities in the mammalian brain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155672

Structural basis of activation of bitter taste receptor T2R1 and comparison with Class A G-protein-coupled receptors (GPCRs)

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155672

Probenecid inhibits the human bitter taste receptor TAS2R16 and suppresses bitter perception of salicin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155672

GABA, its receptors, and GABAergic inhibition in mouse taste buds

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155672

Bitter taste receptors on airway smooth muscle bronchodilate by localized calcium signaling and reverse obstruction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155672

The human bitter taste receptor, hTAS2R16, discriminates slight differences in the configuration of disaccharides.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155672

Insights into the binding of Phenyltiocarbamide (PTC) agonist to its target human TAS2R38 bitter receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155672

Characterization of the beta-D-glucopyranoside binding site of the human bitter taste receptor hTAS2R16.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155672

Modulation of bitter taste perception by a small molecule hTAS2R antagonist

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155672

Structural requirements of bitter taste receptor activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155672

The Molecular Receptive Ranges of Human TAS2R Bitter Taste Receptors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155672

Motile cilia of human airway epithelia are chemosensory

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155672

GABA expression in the mammalian taste bud functions as a route of inhibitory cell-to-cell communication

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155672

High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155672

Genomic organization, expression, and function of bitter taste receptors (T2R) in mouse and rat

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155672

Identification of ligands for two human bitter T2R receptors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155672

Solitary chemoreceptor cells in the nasal cavity serve as sentinels of respiration

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155672

Expression of bitter taste receptors of the T2R family in the gastrointestinal tract and enteroendocrine STC-1 cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155672

T2Rs function as bitter taste receptors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155672

Putative mammalian taste receptors: a class of taste-specific GPCRs with distinct topographic selectivity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155672

gamma-Aminobutyric acid outside the mammalian brain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155672

The bitter pill: clinical drugs that activate the human bitter taste receptor TAS2R14.

5 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.576975

The third intracellular loop plays a critical role in bitter taste receptor activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.576975

Inverse agonism of SQ 29,548 and Ramatroban on Thromboxane A2 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.576975

Bitter taste receptor T2R1 is activated by dipeptides and tripeptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.576975

Functional bitter taste receptors are expressed in brain cells

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25059668

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Receptor Agonism and Antagonism of Dietary Bitter Compounds

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25059668

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Role of rhodopsin N-terminus in structure and function of rhodopsin-bitter taste receptor chimeras

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25059668

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M114.576975

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25059668%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25059668%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25059668%20AND%20SRC:MED&resulttype=core&format=json