(Q34142068)

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Single nucleotide polymorphisms, metabolic activation and environmental carcinogenesis: why molecular epidemiologists should think about enzyme expression

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Europe PubMed Central

PubMed publication ID

31 July 2017

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Europe PubMed Central

Single nucleotide polymorphisms, metabolic activation and environmental carcinogenesis: why molecular epidemiologists should think about enzyme expression (English)

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Europe PubMed Central

PubMed publication ID

31 July 2017

single-nucleotide polymorphism

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based on heuristic

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Williams JA

1

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Europe PubMed Central

PubMed publication ID

31 July 2017

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publication date

1 February 2001

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Europe PubMed Central

PubMed publication ID

31 July 2017

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Europe PubMed Central

PubMed publication ID

31 July 2017

22

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Europe PubMed Central

PubMed publication ID

31 July 2017

2

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Europe PubMed Central

PubMed publication ID

31 July 2017

209-214

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Europe PubMed Central

PubMed publication ID

31 July 2017

Cancer prevention and diet: help from single nucleotide polymorphisms

1 reference

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Does a genotoxic carcinogen contribute to human breast cancer? The value of mutational spectra in unravelling the aetiology of cancer.

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DNA damage in human breast milk cells and its induction by 'early' and 'late' milk extracts

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Myeloperoxidase in human lung lavage. I. A marker of local neutrophil activity

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Hypochlorous acid interactions with thiols, nucleotides, DNA, and other biological substrates

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Peroxidase-mediated irreversible binding of arylamine carcinogens to DNA in intact polymorphonuclear leukocytes activated by a tumor promoter

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Oxidant-dependent metabolic activation of polycyclic aromatic hydrocarbons by phorbol ester-stimulated human polymorphonuclear leukocytes: possible link between inflammation and cancer

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Activation of (+-)-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene to diolepoxides by human polymorphonuclear leukocytes or myeloperoxidase.

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Myeloperoxidase-enhanced formation of (+-)-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene-DNA adducts in lung tissue in vitro: a role of pulmonary inflammation in the bioactivation of a procarcinogen

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An Alu element in the myeloperoxidase promoter contains a composite SP1-thyroid hormone-retinoic acid response element

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Metabolic activation of carcinogens and expression of various cytochromes P450 in human prostate tissue.

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Interindividual variation in the metabolic activation of heterocyclic amines and their N-hydroxy derivatives in primary cultures of human mammary epithelial cells

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DNA adducts of heterocyclic amine food mutagens: implications for mutagenesis and carcinogenesis

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Sulfotransferase catalyzing sulfation of heterocyclic amines

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N-acetyl transferase 2 genotypes, meat intake and breast cancer risk.

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Breast cancer, heterocyclic aromatic amines from meat and N-acetyltransferase 2 genotype

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Metabolism of chemical carcinogens

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Sulfotransferase-mediated activation of mutagens studied using heterologous expression systems

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A 7-hydroxymethyl sulfate ester as an active metabolite of 7,12-dimethylbenz[alpha]anthracene

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Factors determining dietary intakes of heterocyclic amines in cooked foods

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Association between functional genetic polymorphisms of human sulfotransferases 1A1 and 1A2

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Phenol sulfotransferase pharmacogenetics in humans: association of common SULT1A1 alleles with TS PST phenotype

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Metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine by human cytochrome P4501A1, P4501A2 and P4501B1.

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Detection of three genetic polymorphisms in the 5'-flanking region and intron 1 of human CYP1A2 in the Japanese population.

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21 January 2018

Functional significance of a C-->A polymorphism in intron 1 of the cytochrome P450 CYP1A2 gene tested with caffeine

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The 1996 Veylien Henderson Award of the Society of Toxicology of Canada. Current concepts: neutrophils and the activation of carcinogens in the breast and other organs

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The metabolism of 17 beta-estradiol by lactoperoxidase: a possible source of oxidative stress in breast cancer

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Mechanism of formation and structural characterization of DNA adducts derived from peroxidative activation of benzidine

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The novel cholesterol-lowering drug SR-12813 inhibits cholesterol synthesis via an increased degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase

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Immunochemical detection of arylamine N-acetyltransferase in normal and neoplastic bladder

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Expression of arylamine N-acetyltransferase in human intestine

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Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines

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Identifiers

10.1093/CARCIN/22.2.209

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

ResearchGate publication ID

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