(Q34143227)

31 July 2017

title

A macrophage NBR1-MEKK3 complex triggers JNK-mediated adipose tissue inflammation in obesity (English)

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31 July 2017

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8

Matthias H Tschöp

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31 July 2017

7

Timo D Müller

1 reference

31 July 2017

Eloy D Hernandez

1

1 reference

31 July 2017

Sang Jun Lee

2

1 reference

31 July 2017

Ji Young Kim

3

1 reference

31 July 2017

Angeles Duran

4

1 reference

31 July 2017

Juan F Linares

5

1 reference

31 July 2017

Tomoko Yajima

6

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31 July 2017

Steven R Smith

9

1 reference

31 July 2017

Maria T Diaz-Meco

10

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31 July 2017

Jorge Moscat

11

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31 July 2017

publication date

17 July 2014

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31 July 2017

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31 July 2017

volume

20

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31 July 2017

issue

3

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31 July 2017

page(s)

499-511

1 reference

In vivo JNK activation in pancreatic β-cells leads to glucose intolerance caused by insulin resistance in pancreas

31 July 2017

cites work

1 reference

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JNK expression by macrophages promotes obesity-induced insulin resistance and inflammation

5 July 2018

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Inflammation and lipid signaling in the etiology of insulin resistance

5 July 2018

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Feedback on fat: p62-mTORC1-autophagy connections

5 July 2018

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Saturated fatty acids induce c-Src clustering within membrane subdomains, leading to JNK activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156534

Selective inactivation of c-Jun NH2-terminal kinase in adipose tissue protects against diet-induced obesity and improves insulin sensitivity in both liver and skeletal muscle in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156534

Inflammatory mechanisms in obesity

5 July 2018

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NBR1 is a new PB1 signalling adapter in Th2 differentiation and allergic airway inflammation in vivo

5 July 2018

1 reference

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PKCzeta-regulated inflammation in the nonhematopoietic compartment is critical for obesity-induced glucose intolerance

5 July 2018

1 reference

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PB1 domain interaction of p62/sequestosome 1 and MEKK3 regulates NF-kappaB activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156534

Spred2 interaction with the late endosomal protein NBR1 down-regulates fibroblast growth factor receptor signaling

5 July 2018

1 reference

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Of the atypical PKCs, Par-4 and p62: recent understandings of the biology and pathology of a PB1-dominated complex

5 July 2018

1 reference

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A role for NBR1 in autophagosomal degradation of ubiquitinated substrates

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156534

A stress signaling pathway in adipose tissue regulates hepatic insulin resistance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156534

Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals

5 July 2018

1 reference

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A predominant role for parenchymal c-Jun amino terminal kinase (JNK) in the regulation of systemic insulin sensitivity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156534

Insulin sensitivity: modulation by nutrients and inflammation

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156534

Alternative M2 activation of Kupffer cells by PPARdelta ameliorates obesity-induced insulin resistance.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156534

Adipocyte-derived Th2 cytokines and myeloid PPARdelta regulate macrophage polarization and insulin sensitivity.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156534

JNK1 in hematopoietically derived cells contributes to diet-induced inflammation and insulin resistance without affecting obesity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156534

Metabolic stress signaling mediated by mixed-lineage kinases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156534

Mechanisms of obesity-associated insulin resistance: many choices on the menu

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156534

Obesity induces a phenotypic switch in adipose tissue macrophage polarization

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156534

Signal integration and diversification through the p62 scaffold protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156534

Inflammation and metabolic disorders

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156534

Cell signaling and function organized by PB1 domain interactions.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156534

Macrophages block insulin action in adipocytes by altering expression of signaling and glucose transport proteins.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156534

Inflammation and insulin resistance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156534

Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156534

Oxidative metabolism and PGC-1beta attenuate macrophage-mediated inflammation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156534

Mature-onset obesity and insulin resistance in mice deficient in the signaling adapter p62.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156534

Epidemiologic and economic consequences of the global epidemics of obesity and diabetes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156534

Monocyte and macrophage heterogeneity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156534

The kinase domain of titin controls muscle gene expression and protein turnover

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156534

The chemokine system in diverse forms of macrophage activation and polarization

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156534

Definition of metabolic syndrome: Report of the National Heart, Lung, and Blood Institute/American Heart Association conference on scientific issues related to definition

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156534

Alternative activation of macrophages

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156534

A central role for JNK in obesity and insulin resistance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156534

p62 links β-adrenergic input to mitochondrial function and thermogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156534

Increased Inflammatory Properties of Adipose Tissue Macrophages Recruited During Diet-Induced Obesity

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156534

Family history of diabetes links impaired substrate switching and reduced mitochondrial content in skeletal muscle

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25043814

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Adiposity elevates plasma MCP-1 levels leading to the increased CD11b-positive monocytes in mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25043814

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

NIH research on obesity and type 2 diabetes: providing the scientific evidence base for actions to improve health

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25043814

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CMET.2014.06.008

1 reference

31 July 2017

1 reference

31 July 2017

1 reference