(Q34143422)

31 July 2017

title

Linking cell signaling and the epigenetic machinery (English)

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31 July 2017

Helai P Mohammad

1

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31 July 2017

Stephen B Baylin

series ordinal

2

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31 July 2017

publication date

1 October 2010

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31 July 2017

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31 July 2017

volume

28

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31 July 2017

issue

10

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31 July 2017

page(s)

1033-1038

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Tackling the epigenome: challenges and opportunities for collaboration

31 July 2017

cites work

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Epigenetic reprogramming and induced pluripotency

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Nuclear reprogramming to a pluripotent state by three approaches

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Targeting of de novo DNA methylation throughout the Oct-4 gene regulatory region in differentiating embryonic stem cells

21 January 2018

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G9a-mediated irreversible epigenetic inactivation of Oct-3/4 during early embryogenesis.

21 January 2018

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De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes

21 January 2018

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Synergistic function of DNA methyltransferases Dnmt3a and Dnmt3b in the methylation of Oct4 and Nanog

21 January 2018

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Reprogramming towards pluripotency requires AID-dependent DNA demethylation

21 January 2018

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Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification

21 January 2018

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Role of the murine reprogramming factors in the induction of pluripotency

21 January 2018

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Control of developmental regulators by Polycomb in human embryonic stem cells

21 January 2018

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A bivalent chromatin structure marks key developmental genes in embryonic stem cells

21 January 2018

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Transcription. Repressive transcription

21 January 2018

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Wnt signaling promotes reprogramming of somatic cells to pluripotency

21 January 2018

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NANOG is a direct target of TGFbeta/activin-mediated SMAD signaling in human ESCs

21 January 2018

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Niche-independent symmetrical self-renewal of a mammalian tissue stem cell

21 January 2018

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Embryonic stem cell-derived glial precursors: a source of myelinating transplants

21 January 2018

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Developmental biology. Pluripotent chromatin state

21 January 2018

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Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3

21 January 2018

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A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells

21 January 2018

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The Wnt/beta-catenin pathway directs neuronal differentiation of cortical neural precursor cells

21 January 2018

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Specification of dorsal telencephalic character by sequential Wnt and FGF signaling

21 January 2018

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Role of beta-catenin in the developing cortical and hippocampal neuroepithelium

21 January 2018

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Effects of canonical Wnt signaling on dorso-ventral specification of the mouse telencephalon

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Retinoic acid in the development, regeneration and maintenance of the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Retinoic acid induces neuronal differentiation of a cloned human embryonal carcinoma cell line in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Notch signalling: a simple pathway becomes complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

The canonical Notch signaling pathway: unfolding the activation mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Sonic hedgehog signaling in forebrain development and its interactions with pathways that modify its effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Activator control of nucleosome occupancy in activation and repression of transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Binding reactions: epigenetic switches, signal transduction and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Translating the Histone Code

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Setting and resetting of epigenetic marks in malignant transformation and development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Genome-wide mechanisms of nuclear receptor action

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Discrete roles of STAT4 and STAT6 transcription factors in tuning epigenetic modifications and transcription during T helper cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Transcription factor-specific requirements for coactivators and their acetyltransferase functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Histone demethylase KDM5A is an integral part of the core Notch-RBP-J repressor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Smad transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Bmi1 is essential for cerebellar development and is overexpressed in human medulloblastomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Bmi1 loss produces an increase in astroglial cells and a decrease in neural stem cell population and proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

The retinoblastoma binding protein RBP2 is an H3K4 demethylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Coordinated regulation of transcriptional repression by the RBP2 H3K4 demethylase and Polycomb-Repressive Complex 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

The Notch signaling pathway: transcriptional regulation at Notch target genes

21 January 2018

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https://api.crossref.org/works/10.1038%2FNBT1010-1033

Myc-regulated microRNAs attenuate embryonic stem cell differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Have you seen...?: Micro-managing and restraining pluripotent stem cells by MYC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Loss of miR-200 Inhibition of Suz12 Leads to Polycomb-Mediated Repression Required for the Formation and Maintenance of Cancer Stem Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Long noncoding RNA as modular scaffold of histone modification complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Stem cells and the niche: a dynamic duo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

High-resolution profiling of histone methylations in the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Genomic location analysis by ChIP-Seq

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Epigenetic modifications as therapeutic targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Gene silencing in cancer in association with promoter hypermethylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

The epigenomics of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

The epigenetic progenitor origin of human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Stem cell chromatin patterns: an instructive mechanism for DNA hypermethylation?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Transient inactivation of Rb and ARF yields regenerative cells from postmitotic mammalian muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Stems cells and the pathways to aging and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Epigenetic changes in solid and hematopoietic tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Stem cells and cancer; the polycomb connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Role of polycomb group proteins in stem cell self-renewal and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

The polycomb group protein EZH2 is involved in progression of prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Polycomb CBX7 promotes initiation of heritable repression of genes frequently silenced with cancer-specific DNA hypermethylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Epigenetic stem cell signature in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Linking DNA methylation and histone modification: patterns and paradigms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

An elaborate pathway required for Ras-mediated epigenetic silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

CpG island methylation in a mouse model of lymphoma is driven by the genetic configuration of tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Wnt signalling in stem cells and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Epigenetic disruption of the WNT/beta-catenin signaling pathway in human cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Notch signals control the fate of immature progenitor cells in the intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1010-1033

Identification of the polycomb group protein SU(Z)12 as a potential molecular target for human cancer therapy

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20944593

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Epigenetic modifications and human disease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20944593

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The Ink4/Arf locus is a barrier for iPS cell reprogramming

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20944593

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NBT1010-1033

1 reference

31 July 2017

1 reference