(Q34147144)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22293617%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

title

The impact of plant-pathogen studies on medicinal drug discovery (English)

1 reference

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21 January 2020

1 reference

2

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21 January 2020

author name string

Christian Ottmann

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22293617%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Markus Kaiser

series ordinal

3

1 reference

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21 January 2020

publication date

1 February 2012

1 reference

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21 January 2020

published in

Chemical Society Reviews

1 reference

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21 January 2020

volume

41

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22293617%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22293617%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

page(s)

3168-3178

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22293617%20AND%20SRC:MED&resulttype=core&format=json

Host-microbe interactions: shaping the evolution of the plant immune response

21 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

Coevolution of plants and their pathogens in natural habitats

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

Phytotoxins produced by microbial plant pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

Drug discovery and natural products: end of an era or an endless frontier?

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

Natural products in drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

Identification of direct protein targets of small molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

Natural products and their biological targets: proteomic and metabolomic labeling strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

Building on bortezomib: second-generation proteasome inhibitors as anti-cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

The chemistry and biology of syringolins, glidobactins and cepafungins (syrbactins).

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

A plant pathogen virulence factor inhibits the eukaryotic proteasome by a novel mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

Synthetic and structural studies on syringolin A and B reveal critical determinants of selectivity and potency of proteasome inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

Syrbactin class proteasome inhibitor-induced apoptosis and autophagy occurs in association with p53 accumulation and Akt/PKB activation in neuroblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

Novel proteasome-inhibitory syrbactin analogs inducing endoplasmic reticulum stress and apoptosis in hematological tumor cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

Syringolin A selectively labels the 20 S proteasome in murine EL4 and wild-type and bortezomib-adapted leukaemic cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

Isoform-selective histone deacetylase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

Histone deacetylase inhibitor Helminthosporium carbonum (HC)-toxin suppresses the malignant phenotype of neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

Anti-neuroblastoma activity of Helminthosporium carbonum (HC)-toxin is superior to that of other differentiating compounds in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

Microtubules as a target for anticancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

Studies on macrocyclic lactone antibiotics. VII Structure of a phytotoxin "rhizoxin" produced by Rhizopus chinensis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

Pathogenic fungus harbours endosymbiotic bacteria for toxin production

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

Antimitotic rhizoxin derivatives from a cultured bacterial endosymbiont of the rice pathogenic fungus Rhizopus microsporus

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

Multicentre phase II pharmacological evaluation of rhizoxin. Eortc early clinical studies (ECSG)/pharmacology and molecular mechanisms (PAMM) groups

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

Reaching for high-hanging fruit in drug discovery at protein-protein interfaces

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

The structural basis for 14-3-3:phosphopeptide binding specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

Structure of a 14-3-3 coordinated hexamer of the plant plasma membrane H+ -ATPase by combining X-ray crystallography and electron cryomicroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

Structural view of a fungal toxin acting on a 14-3-3 regulatory complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

A structural rationale for selective stabilization of anti-tumor interactions of 14-3-3 proteins by cotylenin A

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

Fusicoccin signaling reveals 14-3-3 protein function as a novel step in left-right patterning during amphibian embryogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

Fusicoccin-A selectively induces apoptosis in tumor cells after interferon-alpha priming.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

The phytotoxin fusicoccin promotes platelet aggregation via 14-3-3-glycoprotein Ib-IX-V interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

Differentiation of human acute myeloid leukaemia cells in primary culture in response to cotylenin A, a plant growth regulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

Treatment of human promyelocytic leukemia in the SCID mouse model with cotylenin A, an inducer of myelomonocytic differentiation of leukemia cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

Identification and structure of small-molecule stabilizers of 14-3-3 protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

Impaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased Ras signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

Drug discovery in the ubiquitin-proteasome system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

The arms race continues: battle strategies between plants and fungal pathogens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

Twenty years of gibberellin research

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

Auxin and plant-microbe interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

Arabidopsis auxin-resistance gene AXR1 encodes a protein related to ubiquitin-activating enzyme E1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

The F-box protein family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

Auxin regulates SCF(TIR1)-dependent degradation of AUX/IAA proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

The F-box protein TIR1 is an auxin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

Mechanism of auxin perception by the TIR1 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

(+)-7-iso-Jasmonoyl-L-isoleucine is the endogenous bioactive jasmonate

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

Jasmonate perception by inositol-phosphate-potentiated COI1-JAZ co-receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

The Arabidopsis CORONATINE INSENSITIVE1 protein is a jasmonate receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

New natural product biosynthetic chemistry discovered by genome mining

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS15301G

21 January 2018

Identifiers

DOI

10.1039/C2CS15301G

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22293617%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference