(Q34147696)

31 July 2017

title

Dynamic conformational switching in the chemokine ligand is essential for G-protein-coupled receptor activation (English)

1 reference

G protein-coupled receptor

31 July 2017

main subject

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5

Roberto P Garofalo

1 reference

31 July 2017

Prem Raj B Joseph

1

1 reference

31 July 2017

Kirti V Sawant

2

1 reference

31 July 2017

Angela Isley

3

1 reference

31 July 2017

Mesias Pedroza

4

1 reference

31 July 2017

Ricardo M Richardson

6

1 reference

31 July 2017

Krishna Rajarathnam

7

1 reference

31 July 2017

language of work or name

English

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publication date

1 December 2013

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31 July 2017

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31 July 2017

volume

456

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31 July 2017

issue

2

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31 July 2017

page(s)

241-251

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Structure of the chemokine receptor CXCR1 in phospholipid bilayers

31 July 2017

cites work

1 reference

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Protein dynamics and conformational selection in bidirectional signal transduction

28 July 2018

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The monomer-dimer equilibrium and glycosaminoglycan interactions of chemokine CXCL8 regulate tissue-specific neutrophil recruitment

28 July 2018

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Local and global dynamics of the G protein-coupled receptor CXCR1.

28 July 2018

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Interpreting protein chemical shift data

28 July 2018

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The role of conformational ensembles of seven transmembrane receptors in functional selectivity

28 July 2018

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Probing the role of CXC motif in chemokine CXCL8 for high affinity binding and activation of CXCR1 and CXCR2 receptors

28 July 2018

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Induced fit, conformational selection and independent dynamic segments: an extended view of binding events

28 July 2018

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Why does binding of proteins to DNA or proteins to proteins not necessarily spell function?

28 July 2018

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Structural basis for differential binding of the interleukin-8 monomer and dimer to the CXCR1 N-domain: role of coupled interactions and dynamics

28 July 2018

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The origin of allosteric functional modulation: multiple pre-existing pathways

28 July 2018

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Differential activation and regulation of CXCR1 and CXCR2 by CXCL8 monomer and dimer

28 July 2018

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Perturbation waves in proteins and protein networks: applications of percolation and game theories in signaling and drug design.

28 July 2018

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Chemokines and chemokine receptors: an overview.

28 July 2018

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Protein allostery, signal transmission and dynamics: a classification scheme of allosteric mechanisms

28 July 2018

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Recognition dynamics up to microseconds revealed from an RDC-derived ubiquitin ensemble in solution

28 July 2018

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Allostery: absence of a change in shape does not imply that allostery is not at play

28 July 2018

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Conformational complexity of G-protein-coupled receptors

28 July 2018

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Role of intramolecular disulfides in stability and structure of a noncovalent homodimer

28 July 2018

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Structural basis of chemokine receptor function--a model for binding affinity and ligand selectivity

28 July 2018

1 reference

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The dynamic energy landscape of dihydrofolate reductase catalysis

28 July 2018

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Cross-desensitization among CXCR1, CXCR2, and CCR5: role of protein kinase C-epsilon

28 July 2018

1 reference

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Large-scale conformational dynamics of the HIV-1 integrase core domain and its catalytic loop mutants

28 July 2018

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Multiple diverse ligands binding at a single protein site: a matter of pre-existing populations

28 July 2018

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Identification of surface residues of the monocyte chemotactic protein 1 that affect signaling through the receptor CCR2.

28 July 2018

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Folding funnels and binding mechanisms

28 July 2018

1 reference

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Disulfide bridges in interleukin-8 probed using non-natural disulfide analogues: dissociation of roles in structure from function

28 July 2018

1 reference

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Folding funnels, binding funnels, and protein function

28 July 2018

1 reference

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Differential cross-regulation of the human chemokine receptors CXCR1 and CXCR2. Evidence for time-dependent signal generation.

28 July 2018

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Solution structure and basis for functional activity of stromal cell-derived factor-1; dissociation of CXCR4 activation from binding and inhibition of HIV-1.

28 July 2018

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28 July 2018

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Selectivity and antagonism of chemokine receptors

28 July 2018

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Neutrophil activation by monomeric interleukin-8.

28 July 2018

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1H NMR solution structure of an active monomeric interleukin-8

28 July 2018

1 reference

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Analysis and prediction of the different types of beta-turn in proteins

28 July 2018

1 reference

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Turns in peptides and proteins

28 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157346

28 July 2018

https://api.crossref.org/works/10.1042%2FBJ20130148

Three-dimensional structure of interleukin 8 in solution

21 January 2018

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Crystal structure of interleukin 8: symbiosis of NMR and crystallography

28 July 2018

1 reference

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Structure-activity relationships of interleukin-8 determined using chemically synthesized analogs. Critical role of NH2-terminal residues and evidence for uncoupling of neutrophil chemotaxis, exocytosis, and receptor binding activities

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157346

Molecular characterization of the chemokine receptor CXCR3: evidence for the involvement of distinct extracellular domains in a multi‐step model of ligand binding and receptor activation

28 July 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130148

Platelet factor 4 binds to interleukin 8 receptors and activates neutrophils when its N terminus is modified with Glu-Leu-Arg.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130148

Thermodynamic characterization of interleukin-8 monomer binding to CXCR1 receptor N-terminal domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130148

Ligand selectivity and affinity of chemokine receptor CXCR1. Role of N-terminal domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130148

A new protocol for high-yield purification of recombinant human CXCL8((3-72))K11R/G31P expressed in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130148

The Energy Landscapes and Motions of Proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130148

High-resolution, single-molecule measurements of biomolecular motion

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130148

Protein dynamics at Eph receptor-ligand interfaces as revealed by crystallography, NMR and MD simulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130148

Analysis of the backbone dynamics of interleukin-8 by 15N relaxation measurements.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130148

Conformational Variability of Solution Nucelar Magnetic Resonance Structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130148

Hepatitis E vaccine debuts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130148

Structure of a CXC chemokine-receptor fragment in complex with interleukin-8

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130148

A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130148

Phylogenetic analysis of 277 human G-protein-coupled receptors as a tool for the prediction of orphan receptor ligands

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157346

Comparison of the solution nuclear magnetic resonance and crystal structures of interleukin-8

28 October 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130148

CXCL8(3–73)K11R/G31P antagonizes ligand binding to the neutrophil CXCR1 and CXCR2 receptors and cellular responses to CXCL8/IL-8

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130148

Water and molecular chaperones act as weak links of protein folding networks: energy landscape and punctuated equilibrium changes point towards a game theory of proteins

21 January 2018

1 reference

12 December 2020

Neutrophil-activating peptide-2 and melanoma growth-stimulatory activity are functional as monomers for neutrophil activation

1 reference

12 December 2020

Interleukin-8 antagonists generated by N-terminal modification

1 reference

12 December 2020

Mutagenesis studies of interleukin-8. Identification of a second epitope involved in receptor binding

1 reference

12 December 2020

Structural requirements for interleukin-8 function identified by design of analogs and CXC chemokine hybrids

1 reference

12 December 2020

IP-10, a gamma-interferon-inducible protein related to interleukin-8, lacks neutrophil activating properties

1 reference

12 December 2020

Reply to 'A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation'

1 reference

12 December 2020

Identifiers

DOI

10.1042/BJ20130148

1 reference

31 July 2017

1 reference

31 July 2017

1 reference