(Q34149262)

31 July 2017

title

Altered intestinal epithelial homeostasis in mice with intestine-specific deletion of the Krüppel-like factor 4 gene (English)

1 reference

31 July 2017

4

Vincent W Yang

1 reference

31 July 2017

Amr M Ghaleb

1

1 reference

31 July 2017

Beth B McConnell

series ordinal

2

1 reference

31 July 2017

Klaus H Kaestner

series ordinal

3

1 reference

31 July 2017

language of work or name

English

0 references

publication date

9 November 2010

1 reference

31 July 2017

published in

Developmental Biology

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31 July 2017

volume

349

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31 July 2017

issue

2

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31 July 2017

page(s)

310-320

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Expression profiling and pathway analysis of Krüppel-like factor 4 in mouse embryonic fibroblasts

31 July 2017

cites work

1 reference

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5 July 2018

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Esophageal squamous cell dysplasia and delayed differentiation with deletion of krüppel-like factor 4 in murine esophagus

5 July 2018

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KLF4 gene expression is inhibited by the notch signaling pathway that controls goblet cell differentiation in mouse gastrointestinal tract

5 July 2018

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5 July 2018

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5 July 2018

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Haploinsufficiency of Krüppel-like factor 4 promotes adenomatous polyposis coli dependent intestinal tumorigenesis

5 July 2018

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5 July 2018

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5 July 2018

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Loss of Krüppel-like factor 4 expression contributes to Sp1 overexpression and human gastric cancer development and progression

5 July 2018

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5 July 2018

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Novel cross talk of Kruppel-like factor 4 and beta-catenin regulates normal intestinal homeostasis and tumor repression

5 July 2018

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KLF4, p21 and context-dependent opposing forces in cancer

5 July 2018

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The KLF4 tumour suppressor is a transcriptional repressor of p53 that acts as a context-dependent oncogene

5 July 2018

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Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation

5 July 2018

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Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells

5 July 2018

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5 July 2018

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Drastic down-regulation of Krüppel-like factor 4 expression is critical in human gastric cancer development and progression

5 July 2018

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Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration

5 July 2018

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Identification of Krüppel-like factor 4 as a potential tumor suppressor gene in colorectal cancer

5 July 2018

1 reference

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Development and differentiation of the intestinal epithelium

5 July 2018

1 reference

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Enterocyte differentiation marker intestinal alkaline phosphatase is a target gene of the gut-enriched Kruppel-like factor

5 July 2018

1 reference

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Downregulation and growth inhibitory effect of epithelial-type Krüppel-like transcription factor KLF4, but not KLF5, in bladder cancer

5 July 2018

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Transcriptional profiling of Krüppel-like factor 4 reveals a function in cell cycle regulation and epithelial differentiation

5 July 2018

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Down-regulation of gut-enriched Kruppel-like factor expression in esophageal cancer

5 July 2018

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Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB

5 July 2018

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5 July 2018

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Gut-enriched Krüppel-like factor regulates colonic cell growth through APC/beta-catenin pathway

5 July 2018

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The zinc-finger transcription factor Klf4 is required for terminal differentiation of goblet cells in the colon.

5 July 2018

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Colorectal cancer in mice genetically deficient in the mucin Muc2

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022386

Requirement of Math1 for secretory cell lineage commitment in the mouse intestine

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022386

Biology of oral mucosa and esophagus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022386

Expression of the gut-enriched Krüppel-like factor (Krüppel-like factor 4) gene in the human colon cancer cell line RKO is dependent on CDX2.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022386

Krüppel-like factor 4 (gut-enriched Krüppel-like factor) inhibits cell proliferation by blocking G1/S progression of the cell cycle

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022386

The gut-enriched Kruppel-like factor (Kruppel-like factor 4) mediates the transactivating effect of p53 on the p21WAF1/Cip1 promoter

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022386

Control of endodermal endocrine development by Hes-1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022386

A paradoxical reduction in susceptibility to colonic injury upon targeted transgenic ablation of goblet cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022386

Klf4 is a transcription factor required for establishing the barrier function of the skin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022386

Sulphation and secretion of the predominant secretory human colonic mucin MUC2 in ulcerative colitis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022386

Lessons from genetic models of inflammatory bowel disease

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022386

A gene for a novel zinc-finger protein expressed in differentiated epithelial cells and transiently in certain mesenchymal cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022386

Identification and characterization of a gene encoding a gut-enriched Krüppel-like factor expressed during growth arrest

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022386

Distribution of the carbonic anhydrase isoenzymes I, II, and VI in the human alimentary tract

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022386

Villin expression in the visceral endoderm and in the gut anlage during early mouse embryogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022386

Developmental regulation of villin gene expression in the epithelial cell lineages of mouse digestive and urogenital tracts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022386

Cis elements of the villin gene control expression in restricted domains of the vertical (crypt) and horizontal (duodenum, cecum) axes of the intestine.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022386

Selective in vitro degradation of the sialylated fraction of germ-free rat mucins by the caecal flora of the rat.

28 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022386

MUC2 is the prominent colonic mucin expressed in ulcerative colitis

28 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022386

Inflammatory bowel disease

28 October 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2010.11.001

Loss of Klf4 in mice causes altered proliferation and differentiation and precancerous changes in the adult stomach

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YDBIO.2010.11.001

Expression from the proximal promoter of the carbonic anhydrase 1 gene as a marker for differentiation in colon epithelia

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YDBIO.2010.11.001

Quantitative analysis of MUC2 synthesis in ulcerative colitis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2010.11.001

10.1016/J.YDBIO.2010.11.001

7 January 2021

Identifiers

DOI

1 reference

31 July 2017

1 reference

31 July 2017

1 reference