(Q34151598)

31 July 2017

title

In situ growth of a PEG-like polymer from the C terminus of an intein fusion protein improves pharmacokinetics and tumor accumulation (English)

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31 July 2017

1 reference

Weiping Gao

1

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Wenge Liu

object named as

Wenge Liu

2

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author name string

Trine Christensen

3

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31 July 2017

Michael R Zalutsky

4

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31 July 2017

Ashutosh Chilkoti

5

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31 July 2017

language of work or name

English

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publication date

1 September 2010

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Proceedings of the National Academy of Sciences of the United States of America

31 July 2017

published in

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31 July 2017

volume

107

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31 July 2017

issue

38

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31 July 2017

page(s)

16432-16437

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Efficient delivery of bioactive antibodies into the cytoplasm of living cells by charge-conversional polyion complex micelles.

31 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944699

Self-assembling chimeric polypeptide-doxorubicin conjugate nanoparticles that abolish tumours after a single injection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944699

In situ growth of a stoichiometric PEG-like conjugate at a protein's N-terminus with significantly improved pharmacokinetics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944699

Synthesis and evaluation of multivalent branched HPMA copolymer-Fab' conjugates targeted to the B-cell antigen CD20.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944699

Temperature-regulated activity of responsive polymer-protein conjugates prepared by grafting-from via RAFT polymerization.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944699

Nanocarriers as an emerging platform for cancer therapy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944699

Anti-cancer PEG-enzymes: 30 years old, but still a current approach

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944699

Interleukin-12: biological properties and clinical application

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944699

Well-defined protein-polymer conjugates via in situ RAFT polymerization

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944699

Polymer conjugates as anticancer nanomedicines

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944699

Protein ligation: an enabling technology for the biophysical analysis of proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944699

Tumor vascular permeability, accumulation, and penetration of macromolecular drug carriers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944699

Synthesis of uniform protein-polymer conjugates

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944699

Pharmacokinetic and biodistribution properties of poly(ethylene glycol)–protein conjugates

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944699

The dawning era of polymer therapeutics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944699

Structural and biological characterization of pegylated recombinant interferon alpha-2b and its therapeutic implications

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944699

Pegylation: a novel process for modifying pharmacokinetics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944699

Synthesis and characterization of poly(ethylene glycol)-insulin conjugates

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944699

Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944699

Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944699

Semisynthesis of cytotoxic proteins using a modified protein splicing element

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944699

The molecular structure of green fluorescent protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944699

Expressed protein ligation: a general method for protein engineering

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944699

Structure-activity relation of NH2-terminal human parathyroid hormone fragments

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944699

Protein splicing elements: inteins and exteins--a definition of terms and recommended nomenclature

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944699

Structure-activity relationships of glucagon-like peptide-1(7-36)amide: insulinotropic activities in perfused rat pancreases, and receptor binding and cyclic AMP production in RINm5F cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944699

Protein splicing converts the yeast TFP1 gene product to the 69-kD subunit of the vacuolar H(+)-adenosine triphosphatase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944699

Molecular structure of a gene, VMA1, encoding the catalytic subunit of H(+)-translocating adenosine triphosphatase from vacuolar membranes of Saccharomyces cerevisiae

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944699

Site-specific insulin conjugates with enhanced stability and extended action profile.

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1006044107

Hybrid hydrogels assembled from synthetic polymers and coiled-coil protein domains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1006044107

Recombinant protein-co-PEG networks as cell-adhesive and proteolytically degradable hydrogel matrixes. Part I: Development and physicochemical characteristics

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1006044107

Streptavidin as a macroinitiator for polymerization: in situ protein-polymer conjugate formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1006044107

In situ preparation of protein-"smart" polymer conjugates with retention of bioactivity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1006044107

In situ formation of protein-polymer conjugates through reversible addition fragmentation chain transfer polymerization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1006044107

Protein-cross-linked polymeric materials through site-selective bioconjugation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1006044107

Self-cleavable stimulus responsive tags for protein purification without chromatography

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1006044107

Synthesis and in vitro evaluation of enzymatically cross-linked elastin-like polypeptide gels for cartilaginous tissue repair.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1006044107

A recombinant polypeptide extends the in vivo half-life of peptides and proteins in a tunable manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1006044107

Site-Specific Conjugation of a Temperature-Sensitive Polymer to a Genetically Engineered Protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1006044107

Control of protein–ligand recognition using a stimuli-responsive polymer

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1006044107

21 January 2018

1 reference

12 December 2020

The cyclization and polymerization of bacterially expressed proteins using modified self-splicing inteins

1 reference

PubMed

12 December 2020

Studies of the metabolism of I-131-labeled human transferrin

1 reference

PubMed

12 December 2020

Purification of recombinant proteins by fusion with thermally-responsive polypeptides

1 reference

PubMed

12 December 2020

Identifiers

DOI

10.1073/PNAS.1006044107

1 reference

31 July 2017

0 references

1 reference

31 July 2017

1 reference