(Q34152284)

31 July 2017

Inhibition of tryptophan hydroxylase activity and decreased 5-HT1A receptor binding in a mouse model of Huntington's disease (English)

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31 July 2017

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George J Yohrling IV

1

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31 July 2017

George C-T Jiang

2

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31 July 2017

Molly M DeJohn

3

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31 July 2017

Daniel J Robertson

4

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31 July 2017

Kent E Vrana

5

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31 July 2017

Jang-Ho J Cha

6

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31 July 2017

language of work or name

English

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publication date

1 September 2002

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Journal of Neurochemistry

31 July 2017

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31 July 2017

82

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31 July 2017

6

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31 July 2017

1416-1423

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A sensitive radiometric assay for tryptophan hydroxylase applicable to crude extracts

31 July 2017

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01084.X

Blood Monoamine Metabolism in Huntington's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01084.X

Severe deficiencies in dopamine signaling in presymptomatic Huntington's disease mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01084.X

Nitration and inactivation of tyrosine hydroxylase by peroxynitrite

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01084.X

Characterization of the human tryptophan hydroxylase gene promoter. Transcriptional regulation by cAMP requires a new motif distinct from the cAMP-responsive element.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01084.X

Aberrant interactions of transcriptional repressor proteins with the Huntington's disease gene product, huntingtin

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01084.X

Why tryptophan hydroxylase is difficult to purify: a reactive oxygen-derived species-mediated phenomenon that may be implicated in human pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01084.X

5-HT1B receptor binding in degenerative movement disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01084.X

Transcriptional dysregulation in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01084.X

Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human huntington disease gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01084.X

Altered neurotransmitter receptor expression in transgenic mouse models of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01084.X

Neonatal 6-hydroxydopa, but not DSP-4, elevates brainstem monoamines and impairs inhibitory avoidance learning in developing rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01084.X

Reduced activity and protein expression of NOS in R6/2 HD transgenic mice: effects of L-NAME on symptom progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01084.X

Hallucinogens, serotonin and obsessive-compulsive disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01084.X

Cannabinoid receptor messenger RNA levels decrease in a subset of neurons of the lateral striatum, cortex and hippocampus of transgenic Huntington's disease mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01084.X

Excitotoxic injury of the neostriatum: a model for Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01084.X

Early kynurenergic impairment in Huntington's disease and in a transgenic animal model

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01084.X

A monoclonal antibody to tryptophan hydroxylase: applications and identification of the epitope

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01084.X

The role of dopamine in motor symptoms in the R6/2 transgenic mouse model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01084.X

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01084.X

Hypothermic and antipyretic effects of ACTH (1-24) and alpha-melanotropin in guinea-pigs

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01084.X

Up-regulation of tryptophan hydroxylase expression and serotonin synthesis by sertraline

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01084.X

Elevated serotonin and reduced dopamine in subregionally divided Huntington's disease striatum

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01084.X

Loss of cortical and thalamic neuronal tenascin-C expression in a transgenic mouse expressing exon 1 of the human Huntington disease gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01084.X

Decreased expression of striatal signaling genes in a mouse model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01084.X

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01084.X

Serotonin receptor binding in a colony model of chronic social stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01084.X

Advances in the molecular characterization of tryptophan hydroxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01084.X

Progressive depletion of complexin II in a transgenic mouse model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01084.X

Recent advances on the pathogenesis of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01084.X

Decreased glutamic acid and increased 5-hydroxytryptamine in Huntington's disease brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01084.X

Brain neurotransmitter deficits in mice transgenic for the Huntington's disease mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01084.X

Polyglutamine pathogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01084.X

Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01084.X

The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01084.X

Polyglutamine-expanded huntingtin promotes sensitization of N-methyl-D-aspartate receptors via post-synaptic density 95.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01084.X

Ventricular fluid homovanillic acid and 5-hydroxyindoleacetic acid concentrations in patients with movement disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01084.X

Serotoninergic system in dementia of the Alzheimer type. Abnormal forms of 5-hydroxytryptophan and serotonin in cerebrospinal fluid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01084.X

Radioenzymatic assay for tryptophan hydroxylase: [3H]H2O release assessed by charcoal adsorption.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01084.X

Recombinant rabbit tryptophan hydroxylase is a substrate for cAMP-dependent protein kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01084.X

10.1046/J.1471-4159.2002.01084.X

21 January 2018

Identifiers

DOI

1 reference

31 July 2017

1 reference