(Q34155940)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22323596%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

title

Small molecule antagonist reveals seizure-induced mediation of neuronal injury by prostaglandin E2 receptor subtype EP2 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22323596%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22323596%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Iris Speigel

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22323596%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Raymond Dingledine

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22323596%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

2

Thota Ganesh

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22323596%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

author name string

Yuhong Du

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22323596%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Yi Quan

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22323596%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Geidy Serrano

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22323596%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Min Qui

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22323596%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Asheebo Rojas

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22323596%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Nadia Lelutiu

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22323596%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

language of work or name

English

0 references

publication date

8 February 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22323596%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

22 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22323596%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

volume

109

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22323596%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22323596%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

page(s)

3149-3154

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22323596%20AND%20SRC:MED&resulttype=core&format=json

Ablation of cyclooxygenase-2 in forebrain neurons is neuroprotective and dampens brain inflammation after status epilepticus

22 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286971

In vitro and in vivo characterization of PF-04418948, a novel, potent and selective prostaglandin EP₂ receptor antagonist

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286971

Microglia in neurodegenerative disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286971

Neuroprotection by selective allosteric potentiators of the EP2 prostaglandin receptor.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286971

Expression of cyclooxygenase-1/-2, microsomal prostaglandin-E synthase-1 and E-prostanoid receptor 2 and regulation of inflammatory mediators by PGE(2) in the amoeboid microglia in hypoxic postnatal rats and murine BV-2 cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286971

Altered hippocampal long-term synaptic plasticity in mice deficient in the PGE2 EP2 receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286971

The prostaglandin E2 EP2 receptor accelerates disease progression and inflammation in a model of amyotrophic lateral sclerosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286971

Modulation of inflammation in brain: a matter of fat.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286971

Prostaglandin E2 receptor subtype 2 (EP2) regulates microglial activation and associated neurotoxicity induced by aggregated alpha-synuclein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286971

Spinal inflammatory hyperalgesia is mediated by prostaglandin E receptors of the EP2 subtype

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286971

Cyclooxygenase-2 (COX-2) in inflammatory and degenerative brain diseases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286971

Reduced susceptibility to ischemic brain injury and N-methyl-D-aspartate-mediated neurotoxicity in cyclooxygenase-2-deficient mice.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286971

The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286971

Cyclooxygenases-1 and -2 are differentially localized to microglia and endothelium in rat EAE and glioma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286971

Cyclooxygenase-2 inhibition prevents delayed death of CA1 hippocampal neurons following global ischemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286971

Sustained induction of prostaglandin endoperoxide synthase-2 by seizures in hippocampus. Inhibition by a platelet-activating factor antagonist

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286971

COX-2, a synaptically induced enzyme, is expressed by excitatory neurons at postsynaptic sites in rat cerebral cortex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286971

Neuroprotective function of the PGE2 EP2 receptor in cerebral ischemia.

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1120195109

Prostaglandin E2 EP1 receptors: downstream effectors of COX-2 neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1120195109

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1120195109

Neuroprotection by the PGE2 EP2 receptor in permanent focal cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1120195109

Deletion of the prostaglandin E2 EP2 receptor reduces oxidative damage and amyloid burden in a model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1120195109

TNF-alpha/IFN-gamma-induced iNOS expression increased by prostaglandin E2 in rat primary astrocytes via EP2-evoked cAMP/PKA and intracellular calcium signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1120195109

Inhibition of pentylenetetrazol-induced seizures in rats by prostaglandin D2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1120195109

Prostaglandin D2 mediates neuronal protection via the DP1 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1120195109

Prostaglandin D2 protects neonatal mouse brain from hypoxic ischemic injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1120195109

Cyclooxygenase-1 in human Alzheimer and control brain: quantitative analysis of expression by microglia and CA3 hippocampal neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1120195109

Spinal prostaglandin E receptors of the EP2 subtype and the glycine receptor α3 subunit, which mediate central inflammatory hyperalgesia, do not contribute to pain after peripheral nerve injury or formalin injection

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1120195109

Cyclooxygenase-2 selectivity of non-steroidal anti-inflammatory drugs and the risk of myocardial infarction and cerebrovascular accident

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22323596

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1120195109

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22323596%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22323596%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22323596%20AND%20SRC:MED&resulttype=core&format=json