(Q34158461)

31 July 2017

IkappaBbeta acts to inhibit and activate gene expression during the inflammatory response (English)

1 reference

Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta

31 July 2017

1 reference

Proto-oncogene c-Rel

1 reference

V-rel reticuloendotheliosis viral oncogene homolog A (avian)

1 reference

Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha

1 reference

10

David Baltimore

1 reference

31 July 2017

Ping Rao

1

1 reference

31 July 2017

Mathew S Hayden

2

1 reference

31 July 2017

Meixiao Long

3

1 reference

31 July 2017

Martin L Scott

4

1 reference

31 July 2017

A Philip West

5

1 reference

31 July 2017

Dekai Zhang

6

1 reference

31 July 2017

Andrea Oeckinghaus

7

1 reference

31 July 2017

Candace Lynch

8

1 reference

31 July 2017

Alexander Hoffmann

9

1 reference

31 July 2017

Sankar Ghosh

11

1 reference

31 July 2017

language of work or name

English

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publication date

1 August 2010

1 reference

31 July 2017

1 reference

31 July 2017

466

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31 July 2017

1115-1119

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31 July 2017

7310

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https://scigraph.springernature.com/pub.10.1038/nature09283

31 July 2017

0 references

cites work

Evidence that cytokines play a role in rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2946371

Harmful molecular mechanisms in sepsis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2946371

Shared principles in NF-kappaB signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2946371

NF-kappaB and the immune response

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2946371

Distinct roles of IkappaB proteins in regulating constitutive NF-kappaB activity.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2946371

RelA/p65 regulation of IkappaBbeta

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2946371

Selective inhibition of NF-kappa B blocks osteoclastogenesis and prevents inflammatory bone destruction in vivo.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2946371

IkappaBalpha/IkappaBepsilon deficiency reveals that a critical NF-kappaB dosage is required for lymphocyte survival.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2946371

X-ray crystal structure of an IkappaBbeta x NF-kappaB p65 homodimer complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2946371

The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2946371

IkappaBbeta, but not IkappaBalpha, functions as a classical cytoplasmic inhibitor of NF-kappaB dimers by masking both NF-kappaB nuclear localization sequences in resting cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2946371

Selective requirement for c-Rel during IL-12 P40 gene induction in macrophages

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2946371

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2946371

NF-kappaB activation provides the potential link between inflammation and hyperplasia in the arthritic joint

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2946371

Functional redundancy of the nuclear factor kappa B inhibitors I kappa B alpha and I kappa B beta

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2946371

Distinct functional properties of IkappaB alpha and IkappaB beta

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2946371

Regulation of IkappaB beta in WEHI 231 mature B cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2946371

Regulation of IkappaBbeta degradation. Similarities to and differences from IkappaBalpha

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2946371

Basal phosphorylation of the PEST domain in the I(kappa)B(beta) regulates its functional interaction with the c-rel proto-oncogene product

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2946371

Role of unphosphorylated, newly synthesized I kappa B beta in persistent activation of NF-kappa B

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2946371

IkappaBalpha deficiency results in a sustained NF-kappaB response and severe widespread dermatitis in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2946371

The PEST-like sequence of I kappa B alpha is responsible for inhibition of DNA binding but not for cytoplasmic retention of c-Rel or RelA homodimers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2946371

Constitutive NF-kappa B activation, enhanced granulopoiesis, and neonatal lethality in I kappa B alpha-deficient mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2946371

Endotoxin-responsive sequences control cachectin/tumor necrosis factor biosynthesis at the translational level

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2946371

The rel-associated pp40 protein prevents DNA binding of Rel and NF-kappa B: relationship with I kappa B beta and regulation by phosphorylation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2946371

Impaired On/Off Regulation of TNF Biosynthesis in Mice Lacking TNF AU-Rich Elements

5 July 2018

1 reference

12 December 2020

IkappaBepsilon-deficient mice: reduction of one T cell precursor subspecies and enhanced Ig isotype switching and cytokine synthesis

1 reference

12 December 2020

Development of anti-TNF therapy for rheumatoid arthritis

1 reference

12 December 2020

Differential expression of interleukin-1 and tumor necrosis factor in murine septic shock models

1 reference

12 December 2020

I kappa B-beta regulates the persistent response in a biphasic activation of NF-kappa B

1 reference

12 December 2020

Identifiers

DOI

10.1038/NATURE09283

1 reference

Dimensions Publication ID

31 July 2017

0 references

1 reference

31 July 2017

1 reference